Usage activity for each article for January to March 2007
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Full-text open-access |
Full-text funded-access |
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“Click Peptides” - Chemical Biology-Oriented Synthesis of Alzheimer's Disease-Related Amyloid β Peptide (Aβ) Analogues Based on the “O-Acyl Isopeptide Method”
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113
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“Parallel” and “Antiparallel Tail-Clamps” Increase the Efficiency of Triplex Formation with Structured DNA and RNA Targets
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ω-Hydrazino Linear Polyethylenimine: A Monoconjugation Building Block for Nucleic Acid Delivery
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32
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1,2,3-Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV-1 Protease Inhibitors
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58
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63
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71
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1-Ethynylpyrene as a Tunable and Versatile Molecular Beacon for DNA
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33
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2′/3′-O-peptidyl Adenosine as a General Base Catalyst of its Own External Peptidyl Transfer: Implications for the Ribosome Catalytic Mechanism
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3′-Enolpyruvyl-UMP, a Novel and Unexpected Metabolite in Nikkomycin Biosynthesis
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18
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3-Hydroxy-3-Methylglutaryl-CoA-Like Synthases Direct the Formation of Methyl and Ethyl Side Groups in the Biosynthesis of the Antibiotic Myxovirescin A
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66
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3-Hydroxybenzene 1,2,4-Trisphosphate, a Novel Second Messenger Mimic and unusual Substrate for Type-I myo-Inositol 1,4,5-Trisphosphate 5-Phosphatase: Synthesis and Physicochemistry
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54
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4-Fluorophenylglycine as a Label for 19F NMR Structure Analysis of Membrane-Associated Peptides
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D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity
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13
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Caenorhabditis elegans: The Cell Lineage and Beyond (Nobel Lecture)
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38
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E and Z α-C-Galactosylceramides by Julia-Lythgoe-Kocienski Chemistry: A Test of the Receptor-Binding Model for Glycolipid Immunostimulants
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29
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N1-Arylsulfonyl-N2-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: A New Class of Calcilytic Agents Acting at the Calcium-Sensing Receptor
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29
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Re-Face Stereospecificity of Methylenetetrahydromethanopterin and Methylenetetrahydrofolate Dehydrogenases is Predetermined by Intrinsic Properties of the Substrate
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9
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7
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Sequence-specific Methyltransferase-Induced Labeling of DNA (SMILing DNA)
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25
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18
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cycloSaligenyl-5-[(E)-2-bromovinyl]-2′-deoxyuridine Monophosphate (cycloSal-BVDUMP) Pronucleotides Active against Epstein-Barr Virus
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2
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2
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2
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4
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2
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scyllo-Inositol Pentakisphosphate as an Analogue of myo-Inositol 1,3,4,5,6-Pentakisphosphate: Chemical Synthesis, Physicochemistry and Biological Applications
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29
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19F NMR Chemical Shifts Induced by a Helical Peptide
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45
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31
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A “Holey” Supramolecular Approach to the Detection of Enzyme Activity
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33
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8
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A (4R)- or a (4S)-Fluoroproline Residue in Position Xaa of the (Xaa-Yaa-Gly) Collagen Repeat Severely Affects Triple-Helix Formation
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25
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A 4′-Phosphopantetheinyl Transferase Mediates Non-Ribosomal Peptide Synthetase Activation in Aspergillus fumigatus
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23
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A Biomimetic Model of Tandem Radical Damage Involving Sulfur-Containing Proteins and Unsaturated Lipids
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11
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A Biosynthetic Classification of Fungal and Streptomycete Fused-Ring Aromatic Polyketides
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44
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A Biosynthetic Pathway to Isovaleryl-CoA in Myxobacteria: The Involvement of the Mevalonate Pathway
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39
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A CD14 Domain with Lipopolysaccharide-Binding and -Neutralizing Activity
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32
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A Caged Uridine for the Selective Preparation of an RNA Fold and Determination of its Refolding Kinetics by Real-Time NMR
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20
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28
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A Central Strategy for Converting Natural Products into Fluorescent Probes
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215
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112
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A Chemically Designed Enzymatic Cleavage Site for Phosphoproteome Analysis
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9
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A Class of Benzenoid Chemicals Suppresses Apoptosis in C. elegans
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A Comparative Analysis of the Sugar Phosphate Cyclase Superfamily Involved in Primary and Secondary Metabolism
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121
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A Cyclic CCK8 Analogue Selective for the Cholecystokinin Type A Receptor: Design, Synthesis, NMR Structure and Binding Measurements
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16
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10
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A DNA Mimic Made of Non-Nucleosidic Phenanthrene Building Blocks
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4
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7
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7
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A Divergent Path of Chlorophyll Breakdown in the Model Plant Arabidopsis thaliana
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23
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9
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7
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A Fast and Efficient Metal-Mediated Oxidation of Isoniazid and Identification of Isoniazid-NAD(H) Adducts
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30
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32
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A Fluid Membrane-Based Soluble Ligand-Display System for Live-Cell Assays
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33
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52
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4
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56
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20
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A Fragment-Based Approach to Understanding Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
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139
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82
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A Fusion of Disciplines: Chemical Approaches to Exploit Fusion Proteins for Functional Genomics
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45
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31
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35
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A Gene Cluster Encoding Rhizoxin Biosynthesis in “Burkholderia rhizoxina”, the Bacterial Endosymbiont of the Fungus Rhizopus microsporus
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119
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147
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A Gene Cluster for Prenylated Naphthoquinone and Prenylated Phenazine Biosynthesis in Streptomyces cinnamonensis DSM 1042
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78
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67
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78
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5
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A Generic Approach to Monofunctionalized Protein-Like Gold Nanoparticles Based on Immobilized Metal Ion Affinity Chromatography
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0
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82
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60
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66
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A Genetically Encoded Pore for the Stochastic Detection of a Protein Kinase
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53
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46
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51
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A Half-Century of Neurotransmitter Research: Impact on Neurology and Psychiatry (Nobel Lecture)
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16
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10
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A High-Throughput Screen for Porphyrin Metal Chelatases: Application to the Directed Evolution of Ferrochelatases for Metalloporphyrin Biosynthesis
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24
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1
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14
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A Homologue of the Mycobacterium tuberculosis PapA5 Protein, Rif-Orf20, Is an Acetyltransferase Involved in the Biosynthesis of Antitubercular Drug Rifamycin B by Amycolatopsis mediterranei S699
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25
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5
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5
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10
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2
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A Homology Model of Penicillin Acylase from Alcaligenes faecalis and In Silico Evaluation of its Selectivity
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0
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0
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0
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18
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4
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1
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5
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3
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A Mass Spectrometric and Molecular Modelling Study of Cisplatin Binding to Transferrin
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0
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0
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23
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18
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2
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20
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5
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A Mass Spectrometry Plate Reader: Monitoring Enzyme Activity and Inhibition with a Desorption/Ionization on Silicon (DIOS) Platform
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0
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0
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0
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28
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1
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18
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A Mechanism of Benzoic Acid Biosynthesis in Plants and Bacteria that Mirrors Fatty Acid β-Oxidation
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37
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17
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5
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22
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9
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A Membrane-Bound Cytochrome c3: A Type II Cytochrome c3 from Desulfovibrio vulgaris Hildenborough
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12
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11
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A Metal-Coordinating DNA Hairpin Mimic
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19
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13
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2
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15
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A Miniature Membrane-less Biofuel Cell Operating at +0.60 V under Physiological Conditions
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50
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34
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4
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38
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6
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A Model for Cell-Surface-Exposed Carbohydrate Moieties Suitable for Structural Studies by NMR Spectroscopy
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0
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0
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0
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0
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56
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41
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3
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44
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1
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A Molecular Mechanism of Enantiorecognition of Tertiary Alcohols by Carboxylesterases
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0
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0
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0
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20
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17
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2
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19
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5
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0
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1
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A Molecular Probe for the Detection of Homopurine Sequences
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0
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0
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0
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0
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54
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137
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9
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146
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14
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A New Chemical Probe for Proteomics of Carbohydrate-Binding Proteins
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0
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0
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0
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0
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84
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51
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10
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61
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8
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0
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A New Class of Arylamine Oxygenases: Evidence that p-Aminobenzoate N-Oxygenase (AurF) is a Di-iron Enzyme and Further Mechanistic Studies
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0
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0
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0
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20
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19
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6
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25
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A New Combined Computational and NMR-Spectroscopical Strategy for the Identification of Additional Conformational Constraints of the Bound Ligand in an Aprotic Solvent
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0
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0
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0
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0
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9
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16
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0
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16
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1
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A New DNA Analogue with Expanded Size and Scope
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0
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0
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0
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17
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6
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1
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7
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9
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A New Embedded Process for Compartmentalized Cell-Free Protein Expression and On-line Detection in Microfluidic Devices
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0
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0
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0
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48
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34
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2
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36
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5
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A New Family of β-Hairpin Mimetics Based on a Trypsin Inhibitor from Sunflower Seeds
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0
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0
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0
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19
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15
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5
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20
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2
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A New Family of Synthetic Diterpenes that Regulates Cytokine Synthesis by Inhibiting IκBα Phosphorylation
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0
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0
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0
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40
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22
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3
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25
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8
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A New Furoxan NO-Donor Rabeprazole Derivative and Related Compounds
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0
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0
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0
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40
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14
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2
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16
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3
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A New Ligand for Immunoglobulin G Subdomains by Screening of a Synthetic Peptide Library
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0
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30
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14
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9
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23
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4
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A New Ligand for Immunoglobulin G Subdomains by Screening of a Synthetic Peptide Library
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0
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0
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0
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3
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3
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0
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3
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0
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0
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0
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0
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A New Mechanism for Ethanol Oxidation Mediated by Cytochrome P450 2E1: Bulk Polarity of the Active Site Makes a Difference
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0
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0
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0
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83
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124
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132
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A New Photoactive Building Block for Investigation of DNA Backbone Interactions: Photoaffinity Labeling of Human DNA Polymerase β
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0
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0
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0
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73
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70
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15
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85
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|
A New Protein Engineering Approach Combining Chemistry and Biology, Part I; Site-Specific Incorporation of 4-Iodo-L-phenylalanine in vitro by Using Misacylated Suppressor tRNAPhe
|
0
|
0
|
0
|
0
|
42
|
48
|
10
|
58
|
8
|
0
|
0
|
0
|
0
|
0
|
|
A New Strategy for the Synthesis of Dinucleotides Loaded with Glycosylated Amino Acids - Investigations on in vitro Non-natural Amino Acid Mutagenesis for Glycoprotein Synthesis
|
0
|
0
|
0
|
0
|
34
|
29
|
0
|
29
|
2
|
0
|
0
|
0
|
0
|
0
|
|
A New Supramolecular Structure Made of Two Different Plasmids Linked by a Circular Oligonucleotide
|
0
|
0
|
0
|
0
|
10
|
10
|
0
|
10
|
4
|
0
|
0
|
0
|
0
|
0
|
|
A New Type of Metalloprotein: The Mo Storage Protein from Azotobacter vinelandii Contains a Polynuclear Molybdenum-Oxide Cluster
|
0
|
0
|
0
|
0
|
27
|
16
|
5
|
21
|
5
|
0
|
1
|
0
|
0
|
0
|
|
A Non-Antibacterial Oxazolidinone Derivative that Inhibits Epithelial Cell Sheet Migration
|
0
|
0
|
0
|
0
|
14
|
11
|
5
|
16
|
0
|
0
|
0
|
0
|
0
|
0
|
|
A Novel Bis-aziridinylnaphthoquinone with Anti-Solid Tumor Activity in which Induced Apoptosis is Associated with Altered Expression Of Bcl-2 Protein
|
0
|
0
|
0
|
0
|
5
|
2
|
2
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
A Novel Cyclodextrin-Derived Tellurium Compound with Glutathione Peroxidase Activity
|
0
|
0
|
0
|
0
|
17
|
7
|
1
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
A Novel Homogenous Assay for Topoisomerase II Action and Inhibition
|
0
|
0
|
0
|
0
|
40
|
16
|
4
|
20
|
8
|
0
|
0
|
0
|
0
|
0
|
|
A Novel Method to Synthesize Versatile Multiple-Branched DNA (MB-DNA) by Reversible Photochemical Ligation
|
0
|
0
|
0
|
0
|
18
|
9
|
2
|
11
|
1
|
0
|
0
|
0
|
0
|
0
|
|
A Novel Mycolactone from a Clinical Isolate of Mycobacterium ulcerans Provides Evidence for Additional Toxin Heterogeneity as a Result of Specific Changes in the Modular Polyketide Synthase
|
0
|
0
|
0
|
0
|
25
|
13
|
5
|
18
|
6
|
0
|
0
|
0
|
0
|
0
|
|
A Novel Near-Infrared Fluorescence Sensor for Detection of Thrombin Activation in Blood
|
0
|
0
|
0
|
0
|
40
|
18
|
2
|
20
|
14
|
0
|
0
|
0
|
0
|
0
|
|
A Parallel Synthesis Scheme for Generating Libraries of DNA Polymerase Substrates and Inhibitors
|
0
|
0
|
0
|
0
|
4
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
A Phenol Quaternary Ammonium Porphyrin as a Potent Telomerase Inhibitor by Selective Interaction with Quadruplex DNA
|
0
|
0
|
0
|
0
|
86
|
59
|
4
|
63
|
6
|
3
|
0
|
0
|
0
|
0
|
|
A Phosphinate-Based Red Fluorescent Probe for Imaging the Superoxide Radical Anion Generated by RAW264.7 Macrophages
|
0
|
0
|
0
|
0
|
76
|
120
|
7
|
127
|
14
|
0
|
0
|
0
|
0
|
0
|
|
A Powerful Antiradiation Compound Revealed by a New High-Throughput Screening Method
|
0
|
0
|
0
|
0
|
36
|
12
|
0
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
A Powerful Combinatorial Screen to Identify High-Affinity Terbium(III)-Binding Peptides
|
0
|
0
|
0
|
0
|
47
|
33
|
4
|
37
|
6
|
0
|
0
|
0
|
0
|
0
|
|
A Practical Enzymatic Synthesis of UDP Sugars and NDP Glucoses
|
0
|
0
|
0
|
0
|
42
|
19
|
6
|
25
|
6
|
0
|
0
|
0
|
0
|
0
|
|
A Proposed Mechanism for the Reductive Ring Opening of the Cyclodiphosphate MEcPP, a Crucial Transformation in the New DXP/MEP Pathway to Isoprenoids Based on Modeling Studies and Feeding Experiments
|
0
|
0
|
0
|
0
|
23
|
11
|
3
|
14
|
6
|
0
|
0
|
0
|
0
|
0
|
|
A Protein Fluorescence Amplifier: Continuous Fluorometric Assay for Rab Geranylgeranyltransferase
|
0
|
0
|
0
|
0
|
60
|
63
|
9
|
72
|
11
|
0
|
0
|
0
|
0
|
0
|
|
A Protein Pre-Organized to Trap the Nucleotide Moiety of Coenzyme B12: Refined Solution Structure of the B12-Binding Subunit of Glutamate Mutase from Clostridium tetanomorphum
|
0
|
0
|
0
|
0
|
10
|
5
|
2
|
7
|
5
|
0
|
0
|
0
|
0
|
0
|
|
A Receptor-Targeted Near-Infrared Fluorescence Probe for In Vivo Tumor Imaging
|
0
|
0
|
0
|
0
|
72
|
44
|
5
|
49
|
17
|
0
|
0
|
0
|
0
|
0
|
|
A Resonance Energy Transfer Immunoassay Based on a Thiol-Reactive Ruthenium Donor Dye and a Longwave-Emitting Acceptor
|
0
|
0
|
0
|
0
|
54
|
80
|
4
|
84
|
3
|
0
|
0
|
0
|
0
|
0
|
|
A Self-Immolative Reporter For β-Galactosidase Sensing
|
0
|
0
|
0
|
0
|
92
|
123
|
15
|
138
|
10
|
0
|
0
|
0
|
0
|
0
|
|
A Short Aib/Ala-Based Peptide Helix Is as Stable as an Ala-Based Peptide Helix Double Its Length
|
0
|
0
|
0
|
0
|
6
|
4
|
1
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
A Signal Released by an Endophytic Attacker Acts as a Substrate for a Rapid Defensive Reaction of the Red Alga Chondrus crispus
|
0
|
0
|
0
|
0
|
11
|
3
|
0
|
3
|
4
|
0
|
0
|
0
|
0
|
0
|
|
A Simple Approach to Well-Defined Sugar-Coated Surfaces for Interaction Studies
|
0
|
0
|
0
|
0
|
58
|
38
|
4
|
42
|
5
|
0
|
0
|
0
|
0
|
0
|
|
A Simple Fluorescence-Spectroscopic Membrane Translocation Assay
|
0
|
0
|
0
|
0
|
116
|
117
|
14
|
131
|
11
|
0
|
0
|
0
|
0
|
0
|
|
A Simple and Efficient Photoaffinity Method for Proteomics of GTP-Binding Proteins
|
0
|
0
|
0
|
0
|
84
|
96
|
1
|
97
|
15
|
0
|
0
|
0
|
0
|
0
|
|
A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G Protein-Coupled Receptor Subtypes
|
0
|
0
|
0
|
0
|
73
|
56
|
8
|
64
|
9
|
0
|
0
|
0
|
0
|
0
|
|
A Small-Molecule-Protein Interaction System with Split-Ubiquitin as Sensor
|
0
|
0
|
0
|
0
|
133
|
96
|
27
|
123
|
31
|
0
|
1
|
0
|
0
|
0
|
|
A Spectrum of Models of Signaling Pathways
|
0
|
0
|
0
|
0
|
53
|
29
|
8
|
37
|
12
|
0
|
0
|
0
|
0
|
0
|
|
A Stable Miniature Protein with Oxaloacetate Decarboxylase Activity
|
0
|
0
|
0
|
0
|
25
|
24
|
0
|
24
|
1
|
0
|
0
|
0
|
0
|
0
|
|
A Stem Cell Molecular Signature: Are There Hallmark Properties That are Shared by all Stem Cells?
|
0
|
0
|
0
|
0
|
11
|
6
|
2
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
A Structural Model of the Complex Formed by Phospholamban and the Calcium Pump of Sarcoplasmic Reticulum Obtained by Molecular Mechanics
|
0
|
0
|
0
|
0
|
16
|
10
|
5
|
15
|
5
|
0
|
0
|
0
|
0
|
0
|
|
A Structure-Activity Guided Strategy for Fluorescent Labeling of Annonaceous Acetogenin Mimetics and their Application in Cell Biology
|
0
|
0
|
0
|
0
|
83
|
248
|
18
|
266
|
11
|
2
|
0
|
0
|
0
|
0
|
|
A Surface Plasmon Resonance Analysis of the Interaction between the Antibiotic Moenomycin A and Penicillin-Binding Protein 1b
|
0
|
0
|
0
|
0
|
20
|
13
|
1
|
14
|
2
|
0
|
0
|
0
|
0
|
0
|
|
A Tale of Two Targets: Differential RNA Selectivity of Nucleobase-Aminoglycoside Conjugates
|
0
|
0
|
0
|
0
|
59
|
55
|
25
|
80
|
20
|
0
|
0
|
0
|
0
|
0
|
|
A Targeted Protease Substrate for a Quantitative Determination of Protease Activities in the Endolysosomal Pathway
|
0
|
0
|
0
|
0
|
90
|
63
|
16
|
79
|
19
|
0
|
0
|
0
|
0
|
0
|
|
A Template-Assembled Synthetic Protein Surface Mimetic of the von Willebrand Factor A1 domain Inhibits Botrocetin-Induced Platelet Aggregation
|
0
|
0
|
0
|
0
|
27
|
18
|
0
|
18
|
3
|
0
|
1
|
0
|
0
|
0
|
|
A Three-State Mechanism of Integrin Activation and Signal Transduction for Integrin αvβ3
|
0
|
0
|
0
|
0
|
9
|
8
|
1
|
9
|
1
|
0
|
0
|
0
|
0
|
0
|
|
A Two-Photon Fluorescence-Correlation Study of Lectins Interacting with Carbohydrated 20 nm Beads
|
0
|
0
|
0
|
0
|
17
|
29
|
2
|
31
|
1
|
0
|
0
|
0
|
0
|
0
|
|
A Two-Photon Fluorescent Probe for Lipid Raft Imaging: C-Laurdan
|
0
|
0
|
0
|
0
|
144
|
155
|
11
|
166
|
13
|
0
|
1
|
0
|
0
|
0
|
|
A Unique Mechanism for Methyl Ester Formation via an Amide Intermediate Found in Myxobacteria
|
0
|
0
|
0
|
0
|
60
|
38
|
4
|
42
|
5
|
0
|
0
|
0
|
0
|
0
|
|
A Virtual Screening Method for Prediction of the hERG Potassium Channel Liability of Compound Libraries
|
0
|
0
|
0
|
0
|
109
|
33
|
6
|
39
|
16
|
0
|
0
|
0
|
0
|
0
|
|
A Water Molecule in the Stereospecificity Pocket of Candida Antarctica Lipase B Enhances Enantioselectivity towards Pentan-2-ol
|
0
|
0
|
0
|
0
|
38
|
48
|
0
|
48
|
11
|
0
|
0
|
0
|
0
|
0
|
|
A Weakly Clustered N terminus Inhibits Aβ(1-40) Amyloidogenesis
|
0
|
0
|
0
|
0
|
29
|
22
|
5
|
27
|
3
|
0
|
0
|
0
|
0
|
0
|
|
A Widely Distributed Bacterial Pathway for Siderophore Biosynthesis Independent of Nonribosomal Peptide Synthetases
|
0
|
0
|
0
|
0
|
89
|
46
|
10
|
56
|
26
|
0
|
0
|
0
|
0
|
0
|
|
AUTHOR INDEX: ChemBioChem 12/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Acceleration of Short Helical Peptide Conformational Dynamics by Trifluoroethanol in an Organic Solvent
|
0
|
0
|
0
|
0
|
8
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Accepting its Random Coil Nature Allows a Partial NMR Assignment of the Neuronal Tau Protein
|
0
|
0
|
0
|
0
|
19
|
6
|
1
|
7
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Acceptor Specificity and Inhibition of the Bacterial Cell-Wall Glycosyltransferase MurG
|
0
|
0
|
0
|
0
|
34
|
25
|
8
|
33
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Access of the Substrate to the Active Site of Yeast Oxidosqualene Cyclase: An Inhibition and Site-Directed Mutagenesis Approach
|
0
|
0
|
0
|
0
|
15
|
13
|
1
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Accumulation of O-GlcNAc-Displaying CdTe Quantum Dots in Cells in the Presence of ATP
|
0
|
0
|
0
|
0
|
150
|
254
|
16
|
270
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Activation of the Anaerobic Ribonucleotide Reductase by S-Adenosylmethionine
|
0
|
0
|
0
|
0
|
13
|
9
|
0
|
9
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Active States of Rhodopsin
|
0
|
0
|
0
|
0
|
19
|
19
|
1
|
20
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Activity-Based Fingerprinting of Proteases
|
0
|
0
|
0
|
0
|
36
|
17
|
3
|
20
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Acyl Transfer in Clorobiocin Biosynthesis: Involvement of Several Proteins in the Transfer of the Pyrrole-2-carboxyl Moiety to the Deoxysugar
|
0
|
0
|
0
|
0
|
17
|
14
|
0
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Adaptation of Class-13 α-Amylases to Diverse Living Conditions
|
0
|
0
|
0
|
0
|
7
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Adding New Tools to the Arsenal of Expressed Protein Ligation
|
0
|
0
|
0
|
0
|
24
|
22
|
4
|
26
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Additivity of Differential Conformational Dynamics in Hyperthermophile/Mesophile Rubredoxin Chimeras as Monitored by Hydrogen Exchange
|
0
|
0
|
0
|
0
|
18
|
16
|
6
|
22
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Addressing the Challenge of Changing the Specificity of RNase T1 with Rational and Evolutionary Approaches
|
0
|
0
|
0
|
0
|
7
|
3
|
1
|
4
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Adeno-Associated Virus Rep78/Rep68 Promotes Localized Melting of the Rep Binding Element in the Absence of Adenosine Triphosphate
|
0
|
0
|
0
|
0
|
7
|
9
|
2
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Adhesion Inhibition of F1C-Fimbriated Escherichia coli and Pseudomonas aeruginosa PAK and PAO by Multivalent Carbohydrate Ligands
|
0
|
0
|
0
|
0
|
33
|
24
|
0
|
24
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Adsorption of Amyloid β (1-40) Peptide at Phospholipid Monolayers
|
0
|
0
|
0
|
0
|
50
|
37
|
2
|
39
|
9
|
0
|
2
|
0
|
0
|
0
|
|
Affinity Chromatography of Tryptases: Design, Synthesis and Characterization of a Novel Matrix-Bound Bivalent Inhibitor
|
0
|
0
|
0
|
0
|
21
|
9
|
0
|
9
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Affinity, Specificity, Diversity: A Challenge for the ABC Transporter TAP in Cellular Immunity
|
0
|
0
|
0
|
0
|
16
|
18
|
0
|
18
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Aldolisation of Bis(glycolaldehyde) Phosphate and Formaldehyde
|
0
|
0
|
0
|
0
|
19
|
13
|
0
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Alkylation of Microperoxidase-11 by the Antimalarial Drug Artemisinin
|
0
|
0
|
0
|
0
|
19
|
12
|
2
|
14
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Allosteric Control of mRNA Decoding
|
0
|
0
|
0
|
0
|
1
|
3
|
1
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Alteration of the Substrate Specificity of Benzoylformate Decarboxylase from Pseudomonas putida by Directed Evolution
|
0
|
0
|
0
|
0
|
32
|
29
|
4
|
33
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Altered Specificity in DNA Binding by the lac Repressor: A Mutant lac Headpiece that Mimics the gal Repressor
|
0
|
0
|
0
|
0
|
26
|
9
|
3
|
12
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Altering Glucose Oxidase to Oxidize D-Galactose through Crosslinking of Imprinted Protein
|
0
|
0
|
0
|
0
|
34
|
8
|
3
|
11
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Altering the Regioselectivity of Cytochrome P450 CYP102A3 of Bacillus subtilis by Using a New Versatile Assay System
|
0
|
0
|
0
|
0
|
55
|
33
|
2
|
35
|
8
|
0
|
0
|
1
|
0
|
0
|
|
Amino(hydroxymethyl)cyclopentanetriols, an Emerging Class of Potent Glycosidase Inhibitors - Part II: Synthesis, Evaluation, and Optimization of β-d-Galactopyranoside Analogues
|
0
|
0
|
0
|
0
|
8
|
3
|
1
|
4
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Aminoacyl Adenylate Substrate Analogues for the Inhibition of Adenylation Domains of Nonribosomal Peptide Synthetases
|
0
|
0
|
0
|
0
|
35
|
24
|
4
|
28
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Aminoglycoside-Hybrid Ligands Targeting the Ribosomal Decoding Site
|
0
|
0
|
0
|
0
|
83
|
51
|
1
|
52
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Aminoglycoside-Quinacridine Conjugates: Towards Recognition of the P6.1 Element of Telomerase RNA
|
0
|
0
|
0
|
0
|
33
|
20
|
5
|
25
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Aminopeptidase P Mediated Detoxification of Organophosphonate Analogues of Sarin: Mechanistic and Stereochemical Study at the Phosphorus Atom of the Substrate
|
0
|
0
|
0
|
0
|
32
|
11
|
0
|
11
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Amplified Telomerase Analysis by Using Rotating Magnetic Particles: The Rapid and Sensitive Detection of Cancer Cells
|
0
|
0
|
0
|
0
|
24
|
20
|
1
|
21
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Amyloid Architecture: Complementary Assembly of Heterogeneous Combinations of Three or Four Peptides into Amyloid Fibrils
|
0
|
0
|
0
|
0
|
13
|
15
|
1
|
16
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Amyloid-Beta Peptide Forms Monomeric Complexes With CuII and ZnII Prior to Aggregation
|
0
|
0
|
0
|
0
|
176
|
217
|
15
|
232
|
42
|
1
|
0
|
0
|
0
|
0
|
|
An Approach towards the Quantitative Structure-Activity Relationships of Caffeic Acid and its Derivatives
|
0
|
0
|
0
|
0
|
42
|
21
|
2
|
23
|
1
|
0
|
0
|
0
|
0
|
0
|
|
An Artificial Primosome: Design, Function, and Applications
|
0
|
0
|
0
|
0
|
2
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
An Atypical Approach Identifies TYR234 as the Key Base Catalyst in Chondroitin AC Lyase
|
0
|
0
|
0
|
0
|
14
|
6
|
0
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
An Axial Met Ligand at a Type 1 Copper Site is Preferable for Fast Electron Transfer
|
0
|
0
|
0
|
0
|
9
|
5
|
0
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
An Efficient Combinatorial Method for the Discovery of Glycosidase Inhibitors
|
0
|
0
|
0
|
0
|
35
|
18
|
5
|
23
|
1
|
0
|
0
|
0
|
0
|
0
|
|
An Efficient Method for the Synthesis of Peptide Aldehyde Libraries Employed in the Discovery of Reversible SARS Coronavirus Main Protease (SARS-CoV Mpro) Inhibitors
|
0
|
0
|
0
|
0
|
91
|
49
|
7
|
56
|
8
|
0
|
0
|
0
|
0
|
0
|
|
An Enzyme Module System for the Synthesis of dTDP-activated Deoxysugars from dTMP and Sucrose
|
0
|
0
|
0
|
0
|
40
|
34
|
7
|
41
|
1
|
0
|
0
|
0
|
0
|
0
|
|
An Error-Prone T7 RNA Polymerase Mutant Generated by Directed Evolution
|
0
|
0
|
0
|
0
|
38
|
19
|
6
|
25
|
8
|
0
|
0
|
0
|
0
|
0
|
|
An Experimental and Molecular-Modeling Study of the Binding of Linked Sulfated Tetracyclitols to FGF-1 and FGF-2
|
0
|
0
|
0
|
0
|
48
|
14
|
4
|
18
|
11
|
0
|
0
|
0
|
0
|
0
|
|
An Inverse Substrate Orientation for the Regioselective Acylation of 3′,5′-Diaminonucleosides Catalyzed by Candida antarctica lipase B?
|
0
|
0
|
0
|
0
|
24
|
20
|
0
|
20
|
2
|
0
|
0
|
0
|
0
|
0
|
|
An Organometallic Route to Oligonucleotides Containing Phosphoroselenoate
|
0
|
0
|
0
|
0
|
3
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
An Unprecedented Catalytic Motif Revealed in the Model Structure of Amide Hydrolyzing Antibody 312d6
|
0
|
0
|
0
|
0
|
13
|
6
|
1
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Analysis of Platinum Adducts with DNA Nucleotides and Nucleosides by Capillary Electrophoresis Coupled to ESI-MS: Indications of Guanosine 5′-Monophosphate O6-N7 Chelation
|
0
|
0
|
0
|
0
|
23
|
12
|
0
|
12
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Analysis of Protein Tyrosine Kinase Inhibitors in Recombinant Yeast Lacking the ERG6 Gene
|
0
|
0
|
0
|
0
|
14
|
16
|
5
|
21
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Analysis of Subunit Interactions in the Iterative Type I Polyketide Synthase ATX from Aspergillus terreus
|
0
|
0
|
0
|
0
|
51
|
54
|
16
|
70
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Annonaceous Acetogenins: The Hydroxyl Groups and THF Rings Are Crucial Structural Elements for Targeting the Mitochondria, Demonstration with the Synthesis of Fluorescent Squamocin Analogues
|
0
|
0
|
0
|
0
|
42
|
32
|
2
|
34
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Anomer-Selective Glycosidase Inhibition by 2-N-Alkylated 1-Azafagomines
|
0
|
0
|
0
|
0
|
20
|
32
|
0
|
32
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Another Face of RNA: Metabolite-Induced “Riboswitching” for Regulation of Gene Expression
|
0
|
0
|
0
|
0
|
10
|
6
|
1
|
7
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Antibiotic and Hemolytic Activity of a β2/β3 Peptide Capable of Folding into a 12/10-Helical Secondary Structure
|
0
|
0
|
0
|
0
|
8
|
7
|
2
|
9
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Antifreeze Glycoproteins - Preventing the Growth of Ice
|
0
|
0
|
0
|
0
|
31
|
17
|
3
|
20
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Antisense Inhibition of Escherichia coli RNase P RNA: Mechanistic Aspects
|
0
|
0
|
0
|
0
|
12
|
5
|
1
|
6
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Anything Goes - Even That RNA Enters the Territory
|
0
|
0
|
0
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Apoptosis Induction and DNA Interstrand Cross-Link Formation by Cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)<
|
0
|
0
|
0
|
0
|
11
|
3
|
1
|
4
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Application of 3-Quinolinoyl Picket Porphyrins to the Electroreduction of Dioxygen to Water: Mimicking the Active Site of Cytochrome c Oxidase
|
0
|
0
|
0
|
0
|
6
|
3
|
2
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Application of Bioluminescence Resonance Energy Transfer (BRET) for Biomolecular Interaction Studies
|
0
|
0
|
0
|
0
|
221
|
133
|
32
|
165
|
43
|
0
|
0
|
0
|
0
|
0
|
|
Application of the Nucleotidylyltransferase Ep toward the Chemoenzymatic Synthesis of dTDP-Desosamine Analogues
|
0
|
0
|
0
|
0
|
17
|
12
|
2
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Aptamer to Ribozyme: The Intrinsic Catalytic Potential of a Small RNA
|
0
|
0
|
0
|
0
|
97
|
35
|
7
|
42
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Are Hormones from the Neuropeptide Y Family Recognized by Their Receptors from the Membrane-Bound State?
|
0
|
0
|
0
|
0
|
23
|
16
|
6
|
22
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Aristoforin, a Novel Stable Derivative of Hyperforin, Is a Potent Anticancer Agent
|
0
|
0
|
0
|
0
|
28
|
25
|
4
|
29
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Artificial Metalloenzymes for Enantioselective Catalysis: Recent Advances
|
0
|
0
|
0
|
0
|
95
|
105
|
10
|
115
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Artificial Metalloproteins with a Ruthenium Tris(bipyridyl) Complex as the Core
|
0
|
0
|
0
|
0
|
30
|
22
|
1
|
23
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Artificial Nucleases
|
0
|
0
|
0
|
0
|
13
|
15
|
3
|
18
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Artificial Transcriptional Activation Domains
|
0
|
0
|
0
|
0
|
49
|
61
|
5
|
66
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Artificial Zinc(II) Complexes Regulate Cell Cycle and Apoptosis-Related Genes in Tumor Cell Lines
|
0
|
0
|
0
|
0
|
130
|
161
|
15
|
176
|
19
|
0
|
0
|
1
|
0
|
0
|
|
As Fast and Selective as Enzymatic Ligations: Unpaired Nucleobases Increase the Selectivity of DNA-Controlled Native Chemical PNA Ligation
|
0
|
0
|
0
|
0
|
25
|
19
|
3
|
22
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Asking the Right Questions
|
0
|
0
|
0
|
0
|
4
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Aspartic Proteases Involved in Alzheimer's Disease
|
0
|
0
|
0
|
0
|
51
|
19
|
2
|
21
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Aspartyl Phosphonates and Phosphoramidates: The First Synthetic Inhibitors of Bacterial Aspartate-Semialdehyde Dehydrogenase
|
0
|
0
|
0
|
0
|
41
|
36
|
1
|
37
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Aspects of Nucleosomal Positional Flexibility and Fluidity
|
0
|
0
|
0
|
0
|
5
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Asprich: A Novel Aspartic Acid-Rich Protein Family from the Prismatic Shell Matrix of the Bivalve Atrina rigida
|
0
|
0
|
0
|
0
|
58
|
34
|
4
|
38
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Assaying Sialyltransferase Activity with Surface Plasmon Resonance
|
0
|
0
|
0
|
0
|
42
|
32
|
1
|
33
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Assembly of Designed Oligonucleotides as an Efficient Method for Gene Recombination: A New Tool in Directed Evolution
|
0
|
0
|
0
|
0
|
41
|
29
|
3
|
32
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Assessing the Structural Stability of Designed β-Hairpin Peptides in the Cytoplasm of Live Cells
|
0
|
0
|
0
|
0
|
57
|
25
|
12
|
37
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Assessment of Chelatable Mitochondrial Iron by Using Mitochondrion-Selective Fluorescent Iron Indicators with Different Iron-Binding Affinities
|
0
|
0
|
0
|
0
|
85
|
92
|
9
|
101
|
22
|
0
|
1
|
0
|
0
|
0
|
|
Assignment of the Nonexchanging Protons of the α-Spectrin SH3 Domain by Two- and Three- Dimensional 1H-13C Solid-State Magic-Angle Spinning NMR and Comparison of Solution and
|
0
|
0
|
0
|
0
|
8
|
8
|
4
|
12
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Asymmetric Synthesis of Water-Soluble Analogues of Galactosylceramide, an HIV-1 Receptor: New Tools to Study Virus-Glycolipid Interactions
|
0
|
0
|
0
|
0
|
19
|
17
|
1
|
18
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Atomic-Force-Microscopy Imaging and Molecular-Recognition-Force Microscopy of Recrystallized Heterotetramers Comprising an S-Layer-Streptavidin Fusion Protein
|
0
|
0
|
0
|
0
|
45
|
24
|
2
|
26
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Atropisomerism, Biphenyls, and Fluorine: A Comparison of Rotational Barriers and Twist Angles
|
0
|
0
|
0
|
0
|
37
|
31
|
0
|
31
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Autodisplay of Active Sorbitol Dehydrogenase (SDH) Yields a Whole Cell Biocatalyst for the Synthesis of Rare Sugars
|
0
|
0
|
0
|
0
|
20
|
6
|
1
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Azide-Alkyne Coupling: A Powerful Reaction for Bioconjugate Chemistry
|
0
|
0
|
0
|
0
|
185
|
127
|
14
|
141
|
27
|
0
|
0
|
0
|
0
|
0
|
|
Azido Sialic Acids Can Modulate Cell-Surface Interactions
|
0
|
0
|
0
|
0
|
43
|
31
|
6
|
37
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Azobenzene as Conformational Switch in Model Peptides
|
0
|
0
|
0
|
0
|
124
|
92
|
20
|
112
|
21
|
0
|
0
|
0
|
0
|
0
|
|
BOOK REVIEWS: ChemBioChem 12/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Backbone and Side-Chain 13C and 15N Signal Assignments of the α-Spectrin SH3 Domain by Magic Angle Spinning Solid-State NMR at 17.6 Tesla
|
0
|
0
|
0
|
0
|
22
|
22
|
3
|
25
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Bacteria Displaying Interleukin-4 Mutants Stimulate Mammalian Cells and Reflect the Biological Activities of Variant Soluble Cytokines
|
0
|
0
|
0
|
0
|
7
|
3
|
0
|
3
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Bacterial Cell Penetration by β3-Oligohomoarginines: Indications for Passive Transfer through the Lipid Bilayer
|
0
|
0
|
0
|
0
|
36
|
31
|
4
|
35
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Bead-Based Cellular Analysis, Sorting and Multiplexing
|
0
|
0
|
0
|
0
|
55
|
24
|
2
|
26
|
9
|
4
|
0
|
0
|
0
|
0
|
|
Behavior Of Silica Aerogel Networks as Highly Porous Solid Solvent Media for Lipases in a Model Transesterification Reaction
|
0
|
0
|
0
|
0
|
16
|
16
|
0
|
16
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Benzofuroindole Analogues as Potent BKCa Channel Openers
|
0
|
0
|
0
|
0
|
120
|
73
|
10
|
83
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Benzophenone Photophore Flexibility and Proximity: Molecular and Crystal-State Structure of a Bpa-Containing Trichogin Dodecapeptide Analogue
|
0
|
0
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0
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0
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4
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0
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2
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2
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0
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0
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0
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0
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0
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0
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Beyond Watson and Crick: DNA Methylation and Molecular Enzymology of DNA Methyltransferases
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0
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0
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0
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0
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197
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58
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10
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68
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26
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0
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0
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0
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Beyond Watson and Crick: DNA Methylation and Molecular Enzymology of DNA Methyltransferases
|
0
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0
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0
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0
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2
|
3
|
1
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4
|
1
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0
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0
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0
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0
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0
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|
Bhc-cNMPs as either Water-Soluble or Membrane-Permeant Photoreleasable Cyclic Nucleotides for both One- and Two-Photon Excitation
|
0
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0
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0
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0
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32
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32
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1
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33
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4
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0
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0
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0
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0
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0
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Bidirectional Control of Gold Nanoparticle Assembly by Turning On and Off DNA Hybridization with Thermally Degradable Molecular Glue
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0
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0
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0
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0
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58
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147
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7
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154
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16
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0
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0
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0
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0
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0
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Bifunctional Ligands that Target Cells Displaying the αvβ3 Integrin
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0
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0
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0
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0
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230
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319
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30
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349
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55
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0
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1
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1
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0
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Big Effects from Small Changes: Possible Ways to Explore Nature's Chemical Diversity
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0
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0
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0
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0
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105
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53
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11
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64
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24
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0
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0
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0
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0
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0
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Binding Mode of TMC-95A Analogues to Eukaryotic 20S Proteasome
|
0
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0
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0
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0
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24
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20
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2
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22
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5
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0
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0
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0
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0
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0
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Binding and Catalysis: A Thermodynamic Study on a Catalytic Antibody System
|
0
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0
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0
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0
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9
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6
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1
|
7
|
1
|
0
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0
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0
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0
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0
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|
Binding and Docking of Synthetic Heterotrimeric Collagen Type IV Peptides with α1β1 Integrin
|
0
|
0
|
0
|
0
|
18
|
12
|
1
|
13
|
0
|
0
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0
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0
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0
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0
|
|
Binding of Helix-Threading Peptides to E. coli 16S Ribosomal RNA and Inhibition of the S15-16S Complex
|
0
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0
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0
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0
|
23
|
17
|
1
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18
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1
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0
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0
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0
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0
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0
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Binding of Insulin to Its Receptor: Towards an Understanding in Three Dimensions
|
0
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0
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0
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0
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22
|
27
|
0
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27
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2
|
0
|
0
|
0
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0
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0
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|
Binding of Organic Anions by Synthetic Supramolecular Metallopores with Internal Mg2+-Aspartate Complexes
|
0
|
0
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0
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0
|
15
|
13
|
0
|
13
|
2
|
0
|
0
|
0
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0
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0
|
|
Binding of Sucrose Octasulphate to the C-Type Lectin-Like Domain of the Recombinant Natural Killer Cell Receptor NKR-P1A Observed by NMR Spectroscopy
|
0
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0
|
0
|
0
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13
|
4
|
1
|
5
|
2
|
0
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0
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0
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0
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0
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|
Bioassay Labels Based on Apoferritin Nanovehicles
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0
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0
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0
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0
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32
|
22
|
2
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24
|
1
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0
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0
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0
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0
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0
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Biocatalysis: Fundamentals and Applications. By Andreas S. Bommarius and Bettina R. Riebel
|
0
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0
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0
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0
|
15
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2
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1
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3
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2
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0
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0
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0
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0
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0
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|
Biocatalysts and Enzyme Technology. By Klaus Buchholz, Volker Kasche, and Uwe Theo Bornscheuer.
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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Bioelectronics - From Theory to Applications. Edited by Itamar Willner and Eugenii Katz.
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0
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0
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0
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0
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8
|
2
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0
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2
|
3
|
0
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0
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0
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0
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0
|
|
Biogenic Silica Patterning: Simple Chemistry or Subtle Biology?
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0
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0
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0
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0
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49
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30
|
8
|
38
|
11
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0
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0
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0
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0
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0
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Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. Edited by Andreas D. Baxevanis and B. F. Francis Ouellette.
|
0
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0
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0
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0
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11
|
2
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0
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2
|
2
|
0
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0
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0
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0
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0
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Biomacromolecular Interactions, Assemblies and Machines: A Structural View
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0
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0
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0
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0
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72
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20
|
7
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27
|
7
|
0
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0
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0
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0
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0
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Biomimetic Studies on Iodothyronine Deiodinase Intermediates: Modeling the Reduction of Selenenyl Iodide by Thiols
|
0
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0
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0
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0
|
2
|
7
|
1
|
8
|
0
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0
|
0
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0
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0
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0
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|
Biomineralization: Progress in Biology, Molecular Biology and Application, 2nd revised ed. Edited by E. Bäuerlein.
|
0
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0
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0
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0
|
9
|
0
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0
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0
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2
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0
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0
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0
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0
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0
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Bionic Catalyst Design: A Photochemical Approach to Artificial Enzyme Function
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0
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0
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0
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0
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27
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16
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2
|
18
|
8
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0
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0
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0
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0
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0
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|
Bioorganic Chemistry Meeting in Wales
|
0
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0
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0
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0
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2
|
2
|
0
|
2
|
0
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0
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0
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0
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0
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0
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|
Biophysical Chemistry. By A. Cooper.
|
0
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0
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0
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0
|
3
|
2
|
0
|
2
|
0
|
0
|
0
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0
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0
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0
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|
Biosynthesis and Identification of Volatiles Released by the Myxobacterium Stigmatella aurantiaca
|
0
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0
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0
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0
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25
|
13
|
0
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Biosynthesis of Carbapenem Antibiotics: New Carbapenam Substrates for Carbapenem Synthase (CarC)
|
0
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0
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0
|
0
|
30
|
13
|
1
|
14
|
1
|
0
|
0
|
0
|
0
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0
|
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Biosynthesis of Proteins Incorporating a Versatile Set of Phenylalanine Analogues
|
0
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0
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0
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0
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45
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38
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5
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43
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11
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0
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0
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0
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0
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0
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Biosynthesis of Volatiles by the Myxobacterium Myxococcus xanthus
|
0
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0
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0
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0
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31
|
14
|
2
|
16
|
3
|
0
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0
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0
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0
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0
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Biosynthesis of the 2-Pyridone Tenellin in the Insect Pathogenic Fungus Beauveria bassiana
|
0
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0
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0
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0
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153
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216
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9
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225
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31
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2
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0
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1
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0
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0
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Biosynthesis of the Heat-Shock Protein 90 Inhibitor Geldanamycin: New Insight into the Formation of the Benzoquinone Moiety
|
0
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0
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0
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0
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35
|
20
|
1
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21
|
2
|
0
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0
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0
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0
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0
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Biosynthetic Incorporation of Fluorohistidine into Proteins in E. coli: A New Probe of Macromolecular Structure
|
0
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0
|
0
|
0
|
16
|
6
|
4
|
10
|
5
|
0
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0
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0
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0
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0
|
|
Biosynthetic Precursors of Fungal Pyrrolizidines, the Loline Alkaloids
|
0
|
0
|
0
|
0
|
4
|
7
|
0
|
7
|
0
|
0
|
0
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0
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0
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0
|
|
Biosynthetic Precursors of Fungal Pyrrolizidines, the Loline Alkaloids
|
0
|
0
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0
|
0
|
22
|
21
|
1
|
22
|
1
|
0
|
0
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0
|
0
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0
|
|
Biotin-Functionalized Cellulose-Based Monolayers as Sensitive Interfaces for the Detection of Single Molecules
|
0
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0
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0
|
0
|
20
|
20
|
0
|
20
|
2
|
0
|
0
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0
|
0
|
0
|
|
Bisubstrate Inhibitors of the Enzyme Catechol O-Methyltransferase (COMT): Efficient Inhibition Despite the Lack of a Nitro Group
|
0
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0
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0
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0
|
21
|
13
|
2
|
15
|
1
|
0
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0
|
0
|
0
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0
|
|
Bivalent Peptides as Models for Multimeric Targets of PDZ Domains
|
0
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0
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0
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0
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160
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162
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13
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175
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32
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0
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1
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0
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0
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0
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|
Bleomycin is a Potent Small-Molecule Inhibitor of Hepatitis C Virus Replication
|
0
|
0
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0
|
0
|
16
|
32
|
8
|
40
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Body Shaping under Water Stress: Osmosensing and Osmoregulation of Solute Transport in Bacteria
|
0
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0
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0
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0
|
27
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14
|
2
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16
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6
|
2
|
0
|
0
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0
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0
|
|
Book Review: An Introduction to Computational Biochemistry. By C. Stan Tsai
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0
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0
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0
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0
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2
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1
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0
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1
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0
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0
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0
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0
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0
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0
|
|
Book Review: An Introduction to Tissue-Biomaterial Interactions. By Kay C. Dee, David A. Puleo and Rena Bizios
|
0
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0
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0
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0
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3
|
1
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0
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1
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2
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0
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0
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0
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0
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0
|
|
Book Review: Analysing Gene Expression - A Handbook of Methods, Possibilities and Pitfalls. Edited by S. Lorkowski and P. Cullen
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0
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0
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0
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0
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7
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1
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0
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1
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1
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0
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0
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0
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0
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0
|
|
Book Review: Antimalarial Chemotherapy Mechanisms of Action, Resistance, and New Directions in Drug Discovery Edited by Philip J. Rosenthal
|
0
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0
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0
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0
|
9
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1
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0
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1
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1
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0
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0
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0
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0
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0
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|
Book Review: Apoptosis and Autoimmunity - From Mechanisms to Treatments Edited byJoachim R. Kalden and Martin Herrmann
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0
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0
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0
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0
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4
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0
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0
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0
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0
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0
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0
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0
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0
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0
|
|
Book Review: BioNMR in Drug Research Edited by Oliver Zerbe
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0
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0
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0
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0
|
6
|
1
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0
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1
|
0
|
0
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0
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0
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0
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0
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|
Book Review: Bioinformatics - From Genomes to Drugs, Volumes I+II, Edited by Thomas Lengauer
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0
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0
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0
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0
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2
|
1
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0
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1
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0
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0
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0
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0
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0
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0
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|
Book Review: Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery. Edited by Angela K. Dillow and Anthony M. Lowman
|
0
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0
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0
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0
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1
|
2
|
1
|
3
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0
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0
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0
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0
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0
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0
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|
Book Review: Biopolymers, Volume 1: Lignin, Humic Substances and Coal Edited by M. Hofrichter and A. Steinbüchel
|
0
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0
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0
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0
|
5
|
2
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0
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2
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0
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0
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0
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0
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0
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0
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Book Review: Biopolymers, Volume 2: Polyisoprenoids Edited by T. Koyama and A. Steinbüchel
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0
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0
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0
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0
|
6
|
1
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0
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1
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Book Review: Capillary Electrophoresis of Nucleic Acids Volumes I and II Edited by Keith R. Mitchelson and Jing Cheng
|
0
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0
|
0
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0
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1
|
1
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2
|
3
|
0
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0
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0
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0
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0
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0
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Book Review: Carbohydrate-Based Drug Discovery, Volumes 1 & 2 . Edited by Chi-Huey Wong
|
0
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0
|
0
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0
|
7
|
4
|
0
|
4
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0
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0
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0
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0
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0
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0
|
|
Book Review: Catalysis from A to Z. Edited by Boy Cornils, Wolfgang A. Herrmann, Robert Schlögl and Chi-Huey Wong
|
0
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0
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0
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0
|
6
|
3
|
0
|
3
|
0
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0
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0
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0
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0
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0
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Book Review: Cell Cycle Inhibitors in Cancer Therapy - Current Strategies. Edited by A. Giordano and K. J. Soprano
|
0
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0
|
0
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0
|
5
|
0
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0
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0
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1
|
0
|
0
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0
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0
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0
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|
Book Review: Cellular Proteins and their Fatty Acids in Health and Disease. Edited by Asim K. Duttaroy and Friedrich Spener
|
0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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0
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Book Review: Chemical Sciences in the 20th Century - Bridging Boundaries Edited by Carsten Reinhardt
|
0
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0
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0
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0
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2
|
1
|
0
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1
|
0
|
0
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0
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0
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0
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0
|
|
Book Review: Chiral Drugs. Edited by Cynthia A. Challener
|
0
|
0
|
0
|
0
|
0
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
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0
|
|
Book Review: Classics in Total Synthesis II: More Targets, Strategies, Methods.By K.C. Nicolaou and S.A. Snyder
|
0
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0
|
0
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0
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10
|
2
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0
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2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Book Review: Colloids and Interfaces in Life Sciences. By Willem Norde
|
0
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0
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0
|
0
|
9
|
1
|
0
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Book Review: Computational Biochemistry and Biophysics Edited by Oren M. Becker, Alexander D. MacKerell, Jr., Benoît Roux, and Masakatsu Watanabe
|
0
|
0
|
0
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0
|
7
|
3
|
0
|
3
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Book Review: DNA Sequencing Protocols Edited by Colin A. Graham and Alison J. M. Hill
|
0
|
0
|
0
|
0
|
8
|
1
|
0
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1
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Book Review: DNA-Protein Interactions: Principles and Protocols, 2nd. Edition Edited by Tom Moss
|
0
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0
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0
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0
|
4
|
0
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0
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0
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1
|
0
|
0
|
0
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0
|
0
|
|
Book Review: Data Mining in Structural Biology Signal Transduction and Beyond. Edited by I. Schlichting and U. Egner
|
0
|
0
|
0
|
0
|
6
|
2
|
0
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2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Book Review: Directed Molecular Evolution of Proteins or How to Improve Enzymes for Biocatalysis. Edited by Susanne Brakmann and Kai Johnsson
|
0
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0
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0
|
0
|
13
|
5
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0
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5
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1
|
0
|
1
|
0
|
0
|
0
|
|
Book Review: Drug Targeting Technology, Physical⋅Chemical⋅Biological Methods, Edited by Hans Schreier
|
0
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0
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0
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0
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1
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1
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0
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1
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0
|
0
|
0
|
0
|
0
|
0
|
|
Book Review: Drug-Membrane Interactions. Analysis, Drug Distribution, Modelling. By J. K. Seydel and M. Wiese
|
0
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0
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0
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0
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2
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1
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1
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2
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0
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0
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0
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0
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0
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0
|
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Book Review: Encyclopedia of Electrochemistry: Bioelectrochemistry, Volume 9. Edited by George S. Wilson
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0
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0
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0
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0
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5
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1
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0
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1
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2
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0
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0
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0
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0
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0
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|
Book Review: Encyclopedia of Environmental Microbiology. Edited by Gabriel Bitton
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0
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0
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0
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0
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8
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0
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1
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1
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0
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0
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0
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0
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0
|
0
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Book Review: Enzyme Kinetics: A Modern Approach by Alejandro G. Marangoni
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0
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0
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0
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0
|
9
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2
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2
|
4
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2
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0
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0
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0
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0
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0
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Book Review: Enzyme Technologies for Pharmaceutical and Biotechnological Applications. Edited by Herbert A. Kirst, Wu-Kuang Yeh, and Milton J. Zmijewski, Jr.
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0
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0
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0
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0
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9
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0
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0
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0
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2
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0
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0
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0
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0
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0
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Book Review: Flüchten, Mitmachen, Vergessen - Chemiker und Biochemiker in der NS-Zeit. By Ute Deichmann
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Book Review: Functional Genomics Series (Volume III): Frontiers in Computational Genomics. Edited by Michael Y. Galperin and Eugene V. Koonin
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4
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Book Review: Fundamentals of Medicinal Chemistry. By Gareth Thomas.
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Book Review: Gene Probes, Principles and Protocols. Edited by Marilena Aquino de Muro and Ralph Rapley
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Book Review: Genes & Signals, By Mark Ptashne and Alexander Gann
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Book Review: Genomic Protocols Edited by Michael P. Starkey and Ramnath Elaswarapu
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Book Review: Genomic Technologies: Present and Future Edited byDavid J. Galas and Stephen J. McCormack
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2
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Book Review: Genomics of GC-Rich Gram-Positive Bacteria Edited by Antoine Danchin
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5
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Book Review: Glycoscience: Chemistry and Chemical Biology Volumes 1-3. Edited by Bertram Fraser-Reid, Kuniaki Tatsuta and Joachim Thiem
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6
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Book Review: Handbook of Animal Lectins, Properties and Biomedical Applications, by David C. Kilpatrick
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Book Review: Handbook of Chemoinformatics - From Data to Knowledge. Edited by Johann Gasteiger.
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2
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Book Review: Handbook of Combinatorial Chemistry. Drugs, Catalysts, Materials, Volumes 1+2. Edited by K. C. Nicolaou, Rudolf Hanko and Wolfgang Hartwig
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Book Review: Handbook of Copper Pharmacology and Toxicology. Edited by Edward J. Massaro
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3
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Book Review: Handbook of Metalloproteins, Edited by Albrecht Messerschmidt, Robert Huber, Thomas Poulos and Karl Wieghardt
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12
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2
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Book Review: Handbook of Nucleoside Synthesis by Helmut Vorbrüggen and Carmen Ruh-Pohlenz
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12
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4
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Book Review: Handbook on Metalloproteins, Edited by Ivano Bertini, Astrid Sigel and Helmut Sigel
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2
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Book Review: Heme, Chlorophyll, and Bilins Methods and Protocols. Edited by Alison G. Smith and Michael Witty
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2
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Book Review: Hydrolysis in Drug and Prodrug Metabolism: Chemistry, Biochemistry and Enzymology. By Berbard Testa and Joachim M. Mayer
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10
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3
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3
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Book Review: Interleukin Protocols. Edited by Luke A. J. O'Neill and Andrew Bowie
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4
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Book Review: Ion Channel Localization. Methods and Protocols. Edited by Anatoli N. Lopatin and Colin G. Nichols
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4
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Book Review: Making Genes, Making Waves. By Jon Beckwith
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2
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Book Review: Mass Spectrometry in Drug Discovery Edited by David T. Rossi and Michael W. Sinz
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21
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4
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4
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Book Review: Matrix Metalloproteinase Protocols Edited by Ian M.Clark
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6
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Book Review: Membrane Transporters: Methods and Protocols. Edited by Qing Yan
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7
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1
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Book Review: Methods and Principles in Medicinal Chemistry Vol. 21: Molecular Biology in Medicinal Chemistry. Edited by Theodor Dingermann, Dieter Steinhilber and Gerd Folkers.
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4
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Book Review: Methods in Molecular Biology Vol. 237: G Protein Signaling: Methods and Protocols. Edited by Alan V. Smrcka
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5
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Book Review: Methods in Molecular Biology, Vol. 228: Membrane Protein Protocols: Expression, Purification and Characterization. Edited by Barry S. Selinsky
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12
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Book Review: Methods in Molecular Biology, Vol. 230: Directed Enzyme Evolution: Screening and Selection Methods. Edited by F. H. Arnold and G. Georgiou
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6
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Book Review: Methods in Molecular Biology, Vol. 232: Protein Misfolding and Disease: Principles and Methods. Edited by Peter Bross and Niels Gregerson.
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6
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Book Review: Methods in Molecular Biology, Vol. 233: Protein Kinase C Protocols. Edited by Alexandra C. Newton
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4
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Book Review: Microbial Transport Systems. Edited by G. Winkelmann
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Book Review: Microsystem Engineering of Lab-on-a-Chip Devices. Edited by Oliver Geschke, Henning Klank, and Pieter Telleman.
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4
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Book Review: Modern Methods of Drug Discovery. Edited by Alexander Hillisch and Rolf Hilgenfeld
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9
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3
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3
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Book Review: Molecular Biology and Biotechnology Edited by John M. Walker and Ralph Rapley
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4
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Book Review: Molecular Devices and Machines byVincenzo Balzani, Margherita Venturi andAlberto Credi
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Book Review: Molecular Modeling - Basic Principles and Applications, Second Edition. By Hans-Dieter Höltje, Wolfgang Sippl, Didier Rognan, and Gerd Folkers.
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Book Review: Neurotransmitters and Neuromodulators: Handbook of Receptors and Biological Effects, By Oliver von Bohlen und Halbach and Rolf Dermitzel
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6
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Book Review: Peptide Arrays on Membrane Supports - Synthesis and Applications. Editors Joachim Koch and Michael Mahler
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10
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4
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Book Review: Peptide Nucleic Acids - Methods and Protocols. Edited by P. E. Nielsen
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5
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Book Review: Peptides: Chemistry and Biology. By Norbert Sewald and Hans-Dieter Jakubke
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Book Review: Pharmaceuticals - Classes, Therapeutic Agents, and Areas of Application, Volumes 1-4 Edited by J. L. McGuire
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Book Review: Pharmacogenomics. The Search for Individualized Therapies. Edited by Julio Licinio and Ma-Li Wong
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5
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Book Review: Plasmids for Therapy and Vaccination Edited by M. Schleef
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Book Review: Pocket Guide to Biotechnology and Genetic Engineering. By Rolf D. Schmid
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3
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Book Review: Principles and Practice of Biological Mass Spectrometry By Chhabil Dass
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5
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2
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2
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Book Review: Protein Arrays, Biochips, and Proteomics: The Next Phase of Genomic Discovery. Edited by Joanna S. Albala and Ian Humphery-Smith.
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Book Review: Protein Crystallography in Drug Discovery. Edited by Robert E. Babine and Sherin S. Abdel-Meguid.
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2
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Book Review: Protein Structure, Stability, and Folding. Edited by Kenneth P. Murphy
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7
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Book Review: Protein Structure: Determination, Analysis, and Applications for Drug Discovery. Edited by Daniel I. Chasman
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9
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Book Review: Protein Targeting, Transport & Translocation Edited by Ross E. Dalbey and Gunnar von Heijne
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6
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Book Review: Protein-Ligand Interactions - From Molecular Recognition to Drug Design Methods. Edited by Hans-Joachim Böhm and Gisbert Schneider
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2
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Book Review: Proteoglycan Protocols Edited by Renato V. Iozzo
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2
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1
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Book Review: Quantum Medicinal Chemistry - Methods and Principles in Medicinal Chemistry. Edited by Paolo Carloni and Frank Alber
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4
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Book Review: Recombinant Protein Drugs Edited by P. Buckel
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6
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1
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Book Review: Springer Handbook of Enzymes, Volume 1. Edited by Dietmar Schomburg and Ida Schomburg
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3
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1
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Book Review: Steroid Receptor Methods - Protocols and Assays. Edited by Benjamin A. Lieberman
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4
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2
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Book Review: Tetracyclines in Biology, Chemistry and Medicine. Edited by Mark L. Nelson, Wolfgang Hillen and Robert A. Greenwald
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11
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2
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2
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2
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Book Review: The Art of Scientific Writing. From Student Reports to Professorial Publications in Chemistry and Related Fields. By Hans F. Ebel, Claus Bliefert and William E. Russey.
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Book Review: The Biochemistry of Cell Signalling By Ernst J. M. Helmreich
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7
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3
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3
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Book Review: The Biological Chemistry of the Elements The inorganic chemistry of life by J. J. R. Fraústo da Silva and R. J. P. Williams
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10
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2
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Book Review: The Epigenome - Molecular Hide and Seek. Edited by Stephen Beck and Alexander Olek
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9
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Book Review: The Expanding Role of Mass Spectrometry in Biotechnology. By Gary Siuzdak
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16
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5
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Book Review: Transcription Regulation in Prokaryotes. By Rolf Wagner
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79
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7
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8
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10
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Book Review: Two-Hybrid Systems Methods and Protocols. Edited by Paul N. MacDonald
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17
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3
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4
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Book Review: Virtual Screening for Bioactive Molecules Edited by H.-J. Böhm and G. Schneider
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2
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2
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2
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Book Review: When Cells Die II. A Comprehensive Evaluation of Apoptosis and Programmed Cell Death. Edited by Richard A. Lockshin and Zahra Zakeri.
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1
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2
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Branches on the α-C Atom of Cyclosporin A Residue 3 Result in Direct Calcineurin Inhibition and Rapid Cyclophilin 18 Binding
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Branches on the α-C Atom of Cyclosporin A Residue 3 Result in Direct Calcineurin Inhibition and Rapid Cyclophilin 18 Binding
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0
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6
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2
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Break on through to the Other Side - Biophysics and Cell Biology Shed Light on Cell-Penetrating Peptides
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112
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95
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104
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|
|
Breakdown of Chlorophyll: Electrochemical Bilin Reduction Provides Synthetic Access to Fluorescent Chlorophyll Catabolites
|
0
|
0
|
0
|
0
|
8
|
4
|
2
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Broad Substrate Specificity of Ketoreductases Derived from Modular Polyketide Synthases
|
0
|
0
|
0
|
0
|
27
|
11
|
2
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Bromobalhimycin and Chlorobromobalhimycins - Illuminating the Potential of Halogenases in Glycopeptide Antibiotic Biosyntheses
|
0
|
0
|
0
|
0
|
19
|
10
|
0
|
10
|
1
|
0
|
0
|
0
|
0
|
0
|
|
C-Terminal Fluorescence Labeling of Proteins for Interaction Studies on the Single-Molecule Level
|
0
|
0
|
0
|
0
|
115
|
73
|
16
|
89
|
11
|
0
|
0
|
0
|
0
|
0
|
|
C-Terminal Modifications of a Protein by UAG-Encoded Incorporation of Puromycin during in vitro Protein Synthesis in the Absence of Release Factor 1
|
0
|
0
|
0
|
0
|
33
|
16
|
0
|
16
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Caged Capsaicins: New Tools for the Examination of TRPV1 Channels in Somatosensory Neurons
|
0
|
0
|
0
|
0
|
82
|
85
|
12
|
97
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Calculation of the Redox Potential of the Protein Azurin and Some Mutants
|
0
|
0
|
0
|
0
|
19
|
10
|
2
|
12
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Calix[6]arene-Based Template for X-ray Crystallographic Analysis of Template-Assembled Synthetic Proteins
|
0
|
0
|
0
|
0
|
25
|
25
|
1
|
26
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Carbohydrate Array Analysis of Anti-Tn Antibodies and Lectins Reveals Unexpected Specificities: Implications for Diagnostic and Vaccine Development
|
0
|
0
|
0
|
0
|
70
|
45
|
12
|
57
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Carbohydrate Microarrays
|
0
|
0
|
0
|
0
|
38
|
27
|
0
|
27
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Carbohydrate-Encapsulated Gold Nanoparticles for Rapid Target-Protein Identification and Binding-Epitope Mapping
|
0
|
0
|
0
|
0
|
32
|
42
|
9
|
51
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Carbon Nanotube Delivery of the GFP Gene into Mammalian Cells
|
0
|
0
|
0
|
0
|
139
|
80
|
10
|
90
|
27
|
0
|
0
|
0
|
0
|
0
|
|
Carbon-Detected NMR Experiments To Investigate Structure and Dynamics of Biological Macromolecules
|
0
|
0
|
0
|
0
|
33
|
14
|
6
|
20
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Carboranyl Bisglycosides for the Treatment of Cancer by Boron Neutron Capture Therapy
|
0
|
0
|
0
|
0
|
7
|
5
|
2
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Cascade Signal Amplification for DNA Detection
|
0
|
0
|
0
|
0
|
98
|
102
|
12
|
114
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Catalysis and Rational Engineering of trans-Acting pH6DZ1, an RNA-Cleaving and Fluorescence-Signaling Deoxyribozyme with a Four-Way Junction Structure
|
0
|
0
|
0
|
0
|
41
|
39
|
4
|
43
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Catalysis by Mutants of Methylmalonyl-CoA Mutase: A Theoretical Rationalization for a Change in the Rate-Determining Step
|
0
|
0
|
0
|
0
|
0
|
1
|
1
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Catalytic Antibodies. Edited by Ehud Keinan.
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Catalytic Molecular Beacons
|
0
|
0
|
0
|
0
|
40
|
27
|
6
|
33
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Catalytic Relationships between Type I and Type II Iterative Polyketide Synthases: The Aspergillus parasiticus Norsolorinic Acid Synthase
|
0
|
0
|
0
|
0
|
90
|
74
|
7
|
81
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Catalytically Active Tetramodular 6-Deoxyerythonolide B Synthase Fusion Proteins
|
0
|
0
|
0
|
0
|
7
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Cell Cycle Control and Cell Division: Implications for Chemically Induced Carcinogenesis
|
0
|
0
|
0
|
0
|
30
|
12
|
5
|
17
|
3
|
0
|
1
|
0
|
0
|
0
|
|
Cell-Surface Recognition of Biotinylated Membrane Proteins Requires Very Long Spacer Arms: An Example from Glucose-Transporter Probes
|
0
|
0
|
0
|
0
|
36
|
25
|
6
|
31
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Cell-free Protein Synthesis through Solubilisate Exchange in Water/Oil Emulsion Compartments
|
0
|
0
|
0
|
0
|
19
|
13
|
2
|
15
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Cellular Inhibition of Protein Tyrosine Phosphatase 1B by Uncharged Thioxothiazolidinone Derivatives
|
0
|
0
|
0
|
0
|
280
|
258
|
32
|
290
|
57
|
0
|
0
|
1
|
0
|
0
|
|
Cellular Internalization of Enhanced Green Fluorescent Protein Ligated to a Human Calcitonin-Based Carrier Peptide
|
0
|
0
|
0
|
0
|
25
|
10
|
5
|
15
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Cellular Uptake Studies with β-Peptides
|
0
|
0
|
0
|
0
|
29
|
25
|
2
|
27
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Chain Termination Steps in Nonribosomal Peptide Synthetase Assembly Lines: Directed Acyl-S-Enzyme Breakdown in Antibiotic and Siderophore Biosynthesis
|
0
|
0
|
0
|
0
|
27
|
17
|
3
|
20
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Changing Orders - Primary and Secondary Membrane Transporters Revised
|
0
|
0
|
0
|
0
|
5
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Characterisation of Disulfide-Bond Dynamics in Non-Native States of Lysozyme and Its Disulfide Deletion Mutants by NMR
|
0
|
0
|
0
|
0
|
23
|
14
|
3
|
17
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Characterization and Peroxidase Activity of a Myoglobin Mutant Containing a Distal Arginine
|
0
|
0
|
0
|
0
|
15
|
6
|
3
|
9
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Characterization of BlsM, a Nucleotide Hydrolase Involved in Cytosine Production for the Biosynthesis of Blasticidin S
|
0
|
0
|
0
|
0
|
25
|
27
|
6
|
33
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Characterization of Peroxide-Bound Heme Species Generated in the Reaction of Thermally Tolerant Cytochrome c552 with Hydrogen Peroxide
|
0
|
0
|
0
|
0
|
16
|
11
|
3
|
14
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Characterization of the ZnII Binding to the Peptide Amyloid-β1-16 linked to Alzheimer's Disease
|
0
|
0
|
0
|
0
|
41
|
25
|
4
|
29
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Charge Transfer in DNA: From Mechanism to Application. Edited by Hans-Achim Wagenknecht.
|
0
|
0
|
0
|
0
|
6
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Approaches to Controlling Intracellular Protein Degradation
|
0
|
0
|
0
|
0
|
31
|
20
|
5
|
25
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Biology of the Sugar Code
|
0
|
0
|
0
|
0
|
200
|
97
|
10
|
107
|
34
|
3
|
1
|
0
|
0
|
0
|
|
Chemical Biology: Directing Biosynthesis
|
0
|
0
|
0
|
0
|
49
|
68
|
10
|
78
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Chaperones - A New Concept in Drug Research
|
0
|
0
|
0
|
0
|
35
|
16
|
4
|
20
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Inhibitors when Timing Is Critical: A Pharmacological Concept for the Maturation of T Cell Contacts
|
0
|
0
|
0
|
0
|
21
|
9
|
2
|
11
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Microarrays to Identify Ligands that Bind Pathogenic Cells
|
0
|
0
|
0
|
0
|
48
|
56
|
6
|
62
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Micropatterning of Polycarbonate for Site-Specific Peptide Immobilization and Biomolecular Interactions
|
0
|
0
|
0
|
0
|
107
|
124
|
18
|
142
|
21
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Neuroimmunology: Health in a Nutshell Bidirectional Communication between Immune and Stress (Limbic-Hypothalamic-Pituitary-Adrenal) Systems
|
0
|
0
|
0
|
0
|
18
|
4
|
0
|
4
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Restriction: Strand Cleavage by Ammonia Treatment at 8Oxoguanine Yields Biologically Active DNA
|
0
|
0
|
0
|
0
|
4
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Strategies for Activity-Based Proteomics
|
0
|
0
|
0
|
0
|
112
|
78
|
12
|
90
|
20
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Synthesis and Biochemical Properties of Oligonucleotides that Contain the (5′S,5S,6S)-5′,6-Cyclo-5-hydroxy-5,6-dihydro-2′-deoxyuridine DNA Lesion
|
0
|
0
|
0
|
0
|
15
|
10
|
1
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Synthesis of Triple-Labelled Three-Helix Bundle Binding Proteins for Specific Fluorescent Detection of Unlabelled Protein
|
0
|
0
|
0
|
0
|
40
|
29
|
4
|
33
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Chemical Synthesis of a Dual Branched Malto-Decaose: A Potential Substrate for α-Amylases
|
0
|
0
|
0
|
0
|
9
|
4
|
1
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Chemical and Enzymatic Synthesis of Fluorinated-Dehydroalanine-Containing Peptides
|
0
|
0
|
0
|
0
|
23
|
16
|
3
|
19
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Chemical-Reaction-Based Site-Selective DNA Cutter for PCR-Free Gene Manipulation
|
0
|
0
|
0
|
0
|
52
|
34
|
4
|
38
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Chemistry Challenges in SNP Typing
|
0
|
0
|
0
|
0
|
50
|
27
|
5
|
32
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Chemistry and Biology of Hyaluronan. Edited by Hari G. Garg and Charles A. Hales.
|
0
|
0
|
0
|
0
|
10
|
4
|
3
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Chemistry and Ecology of Toxic Birds
|
0
|
0
|
0
|
0
|
55
|
17
|
6
|
23
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Chemistry meets Biology: Chemical Approaches to the Study of Biology
|
0
|
0
|
0
|
0
|
57
|
9
|
2
|
11
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Chemistry of Natural Products. By S. V. Bhat, B. A. Nagasampagi and M. Sivakumar.
|
0
|
0
|
0
|
0
|
7
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Chemistry of Peptide Synthesis. By N. Leo Benoiton.
|
0
|
0
|
0
|
0
|
16
|
4
|
0
|
4
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Chemistry: A Way to the Roots of Biology
|
0
|
0
|
0
|
0
|
13
|
7
|
3
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Chemoenzymatic Synthesis of Biotinylated Nucleotide Sugars as Substrates for Glycosyltransferases
|
0
|
0
|
0
|
0
|
27
|
19
|
5
|
24
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Chemoenzymatic Synthesis of Branched Oligo- and Polysaccharides as Potential Substrates for Starch Active Enzymes
|
0
|
0
|
0
|
0
|
12
|
12
|
0
|
12
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Chemoenzymatic Synthesis of HIV-1 gp41 Glycopeptides: Effects of Glycosylation on the Anti-HIV Activity and α-Helix Bundle-Forming Ability of Peptide C34
|
0
|
0
|
0
|
0
|
24
|
16
|
0
|
16
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Chemoenzymatic Ubiquitination of Artificial Substrates
|
0
|
0
|
0
|
0
|
43
|
20
|
5
|
25
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Chemogenomics in Drug Discovery - A Medicinal Chemistry Perspective. Edited by Hugo Kubinyi and Gerhard Müller.
|
0
|
0
|
0
|
0
|
10
|
3
|
1
|
4
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Chimeras of the Homing Endonuclease PI-SceI and the Homologous Candida tropicalis Intein: A Study to Explore the Possibility of Exchanging DNA-Binding Modules to Obtain Highly Specific Endonucleases with Altered Specificity
|
0
|
0
|
0
|
0
|
11
|
9
|
0
|
9
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Chloroplastic Glycolipids Fuel Aldehyde Biosynthesis in the Marine Diatom Thalassiosira rotula
|
0
|
0
|
0
|
0
|
21
|
17
|
2
|
19
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Chromogenic and Fluorogenic Assays for the Lactonase Activity of Serum Paraoxonases
|
0
|
0
|
0
|
0
|
46
|
26
|
15
|
41
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Circe Effect versus Enzyme Preorganization: What Can Be Learned from the Structure of the Most Proficient Enzyme?
|
0
|
0
|
0
|
0
|
17
|
9
|
1
|
10
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Circular Dichroism of Designed Peptide Helices and β-Hairpins: Analysis of Trp- and Tyr-Rich Peptides
|
0
|
0
|
0
|
0
|
19
|
10
|
1
|
11
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Cisplatin Damage: Are DNA Repair Proteins Saviors or Traitors to the Cell?
|
0
|
0
|
0
|
0
|
62
|
38
|
18
|
56
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Classifying “Kinase Inhibitor-Likeness” by Using Machine-Learning Methods
|
0
|
0
|
0
|
0
|
47
|
27
|
4
|
31
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Classifying Enzymes from Selectivity Fingerprints
|
0
|
0
|
0
|
0
|
18
|
9
|
0
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Cleavable Substrate Containing Molecular Beacons for the Quantification of DNA-Photolyase Activity
|
0
|
0
|
0
|
0
|
5
|
11
|
0
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
CloN6, a Novel Methyltransferase Catalysing the Methylation of the Pyrrole-2-carboxyl Moiety of Clorobiocin
|
0
|
0
|
0
|
0
|
22
|
12
|
1
|
13
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Cloning and Heterologous Expression of the Aranciamycin Biosynthetic Gene Cluster Revealed a New Flexible Glycosyltransferase
|
0
|
0
|
0
|
0
|
79
|
67
|
0
|
67
|
15
|
1
|
0
|
0
|
0
|
0
|
|
Cloning, Functional Expression, and Characterization of Recombinant Pig Liver Esterase
|
0
|
0
|
0
|
0
|
35
|
15
|
4
|
19
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Close-Range Electrostatic Interactions in Proteins
|
0
|
0
|
0
|
0
|
63
|
40
|
4
|
44
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Cofactor-Apoprotein Hydrogen Bonding in Oxidized and Fully Reduced Flavodoxin Monitored by Trans-Hydrogen-Bond Scalar Couplings
|
0
|
0
|
0
|
0
|
18
|
7
|
2
|
9
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Coiled Coil Domains: Stability, Specificity, and Biological Implications
|
0
|
0
|
0
|
0
|
176
|
102
|
32
|
134
|
36
|
0
|
0
|
0
|
0
|
0
|
|
Combinatorial Approaches To Novel Proteins
|
0
|
0
|
0
|
0
|
17
|
10
|
2
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Combinatorial Biosynthesis of Antibiotics: Challenges and Opportunities
|
0
|
0
|
0
|
0
|
78
|
52
|
6
|
58
|
16
|
0
|
0
|
0
|
0
|
0
|
|
Combinatorial Biosynthesis of Carotenoids in a Heterologous Host: A Powerful Approach for the Biosynthesis of Novel Structures
|
0
|
0
|
0
|
0
|
40
|
20
|
3
|
23
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Combinatorial Self-Assembly of Cyclophilin hCyp-18 Ligands through Rhenium Coordination
|
0
|
0
|
0
|
0
|
11
|
12
|
0
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Combinatorial Strategies for Targeting Protein Families: Application to the Proteases
|
0
|
0
|
0
|
0
|
35
|
33
|
5
|
38
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Combinatorial Synthesis of New Cationic Lipids and High-Throughput Screening of Their Transfection Properties
|
0
|
0
|
0
|
0
|
19
|
13
|
1
|
14
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Combined Biosynthetic Pathway For De Novo Production of UDP-Galactose: Catalysis with Multiple Enzymes Immobilized on Agarose Beads
|
0
|
0
|
0
|
0
|
17
|
14
|
1
|
15
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Combining Chemical and Biological Techniques to Produce Modified Proteins
|
0
|
0
|
0
|
0
|
12
|
13
|
4
|
17
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Common Inhibition of Both β-Glucosidases and β-Mannosidases by Isofagomine Lactam Reflects Different Conformational Itineraries for Pyranoside Hydrolysis
|
0
|
0
|
0
|
0
|
17
|
10
|
3
|
13
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Comparative Analysis of Putative Agonist-Binding Modes in the Human A1 Adenosine Receptor
|
0
|
0
|
0
|
0
|
21
|
15
|
2
|
17
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Comparative Study of Purine and Pyrimidine Nucleoside Analogues Acting on the Thymidylate Kinases of Mycobacterium tuberculosis and of Humans
|
0
|
0
|
0
|
0
|
41
|
17
|
4
|
21
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Comparison of Fertilinβ-Peptide-Substituted Polymers and Liposomes as Inhibitors of In Vitro Fertilization
|
0
|
0
|
0
|
0
|
7
|
3
|
0
|
3
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Comparison of the Chemical Properties of Iron and Cobalt Porphyrins and Corrins
|
0
|
0
|
0
|
0
|
95
|
19
|
0
|
19
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Comparison of the NMR Spectroscopy Solution Structures of Pyranosyl-RNA and Its Nucleo-δ-peptide Analogue
|
0
|
0
|
0
|
0
|
9
|
2
|
1
|
3
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Competitive MS Binding Assays for Dopamine D2 Receptors Employing Spiperone as a Native Marker
|
0
|
0
|
0
|
0
|
21
|
11
|
2
|
13
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Complex Formation of Divalent Metal Ions with Uridine 5′-O-Thiomonophosphate or Methyl Thiophosphate: Comparison of Complex Stabilities with Those of the Parent Phosphate Ligands
|
0
|
0
|
0
|
0
|
14
|
4
|
1
|
5
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Complexation of Fatty Acids and Fatty Acid-CoAs with Synthetic O-Methylated Polysaccharides
|
0
|
0
|
0
|
0
|
59
|
110
|
10
|
120
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Computational Design of Reduced Metabolic Networks
|
0
|
0
|
0
|
0
|
26
|
15
|
7
|
22
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Computational Studies of Subtilisin-Catalyzed Transesterification of Sucrose: Importance of Entropic Effects.
|
0
|
0
|
0
|
0
|
7
|
5
|
3
|
8
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Concepts and Models in Bioinorganic Chemistry. Edited by Heinz-Bernhard Kraatz and Nils Metzler-Nolte.
|
0
|
0
|
0
|
0
|
40
|
26
|
5
|
31
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Conformation Analysis of Aspartame-Based Sweeteners by NMR Spectroscopy, Molecular Dynamics Simulations, and X-ray Diffraction Studies
|
0
|
0
|
0
|
0
|
49
|
20
|
7
|
27
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Conformation Analysis of Glu181 and Ser186 in the Metarhodopsin I State
|
0
|
0
|
0
|
0
|
13
|
17
|
1
|
18
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Conformational Features of Human Melanin-Concentrating Hormone: An NMR and Computational Analysis
|
0
|
0
|
0
|
0
|
12
|
9
|
1
|
10
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Conformationally Gated Electrochemical Gene Detection
|
0
|
0
|
0
|
0
|
38
|
26
|
5
|
31
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Conjugated Polyelectrolytes - Conformation-Sensitive Optical Probes for Staining and Characterization of Amyloid Deposits
|
0
|
0
|
0
|
0
|
61
|
131
|
16
|
147
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Consensus Design of Repeat Proteins
|
0
|
0
|
0
|
0
|
35
|
24
|
2
|
26
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Conserved Amino Acid Residues Correlating With Ketoreductase Stereospecificity in Modular Polyketide Synthases
|
0
|
0
|
0
|
0
|
25
|
25
|
3
|
28
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Construction of an Artificial Receptor Protein (“Anticalin”) Based on the Human Apolipoprotein D
|
0
|
0
|
0
|
0
|
54
|
29
|
2
|
31
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Control and Selectivity of Photosensitized Singlet Oxygen Production: Challenges in Complex Biological Systems
|
0
|
0
|
0
|
0
|
76
|
104
|
11
|
115
|
17
|
1
|
0
|
0
|
0
|
0
|
|
Convenient Access Both to Highly Antimalaria-Active 10-Arylaminoartemisinins, and to 10-Alkyl Ethers Including Artemether, Arteether, and Artelinate
|
0
|
0
|
0
|
0
|
34
|
13
|
1
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Convergent Glycopeptide Synthesis by Traceless Staudinger Ligation and Enzymatic Coupling
|
0
|
0
|
0
|
0
|
44
|
47
|
2
|
49
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Conversion of (2S)-Arginine to (2S,3R)-Capreomycidine by VioC and VioD from the Viomycin Biosynthetic Pathway of Streptomyces sp. Strain ATCC11861
|
0
|
0
|
0
|
0
|
38
|
25
|
5
|
30
|
3
|
0
|
0
|
1
|
0
|
0
|
|
Converting Cytochrome b5 into Cytochrome c-Like Protein
|
0
|
0
|
0
|
0
|
14
|
6
|
3
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Converting Cytochrome c into a Peroxidase-Like Metalloenzyme by Molecular Design
|
0
|
0
|
0
|
0
|
43
|
45
|
2
|
47
|
10
|
0
|
1
|
0
|
0
|
0
|
|
Cooperativity between Electrons and Protons in a Monomeric Cytochrome c3: The Importance of Mechano-Chemical Coupling for Energy Transduction
|
0
|
0
|
0
|
0
|
38
|
5
|
2
|
7
|
0
|
0
|
1
|
0
|
0
|
0
|
|
Copper Binding to the Neurotoxic Peptide PrP106-126: Thermodynamic and Structural Studies
|
0
|
0
|
0
|
0
|
36
|
13
|
3
|
16
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Correlated Mutation Analyses on Very Large Sequence Families
|
0
|
0
|
0
|
0
|
33
|
16
|
5
|
21
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Cotranslational Incorporation of a Structurally Diverse Series of Proline Analogues in an Escherichia coli Expression System
|
0
|
0
|
0
|
0
|
15
|
15
|
0
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Could a Diiron-Containing Four-Helix-Bundle Protein Have Been a Primitive Oxygen Reductase?
|
0
|
0
|
0
|
0
|
18
|
6
|
2
|
8
|
1
|
0
|
0
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0
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0
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0
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|
Cover Picture
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0
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0
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0
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2
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2
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1
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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0
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1
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1
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2
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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0
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1
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2
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3
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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1
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1
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1
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2
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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1
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3
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1
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4
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1
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0
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0
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0
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0
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0
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Cover Picture
|
0
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0
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0
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0
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2
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1
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1
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2
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0
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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0
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2
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1
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3
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1
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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3
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1
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5
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0
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0
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0
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0
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0
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0
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Cover Picture
|
0
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0
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0
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0
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0
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3
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0
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3
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0
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0
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0
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0
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0
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0
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Cover Picture
|
0
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0
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0
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0
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1
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2
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1
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3
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0
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0
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0
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0
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0
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0
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Cover Picture
|
0
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0
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0
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0
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2
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16
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0
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16
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2
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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1
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3
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1
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1
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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1
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4
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1
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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1
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Cover Picture
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0
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0
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4
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0
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4
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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1
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1
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1
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2
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0
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0
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0
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0
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0
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Cover Picture
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0
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0
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0
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0
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3
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0
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0
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0
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0
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0
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0
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|
Cover Picture: 1,2,3-Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV-1 Protease Inhibitors (ChemBioChem 7/2005)
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0
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0
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0
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0
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4
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9
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0
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9
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0
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0
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0
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0
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0
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Cover Picture: A Cyclic CCK8 Analogue Selective for the Cholecystokinin Type A Receptor: Design, Synthesis, NMR Structure and Binding Measurements (ChemBioChem 11/2003)
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0
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0
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0
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0
|
3
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2
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0
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2
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1
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0
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0
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0
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0
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0
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Cover Picture: A Fusion of Disciplines: Chemical Approaches to Exploit Fusion Proteins for Functional Genomics (ChemBioChem 9/2003)
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0
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0
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0
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0
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6
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3
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0
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3
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2
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0
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0
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0
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0
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0
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Cover Picture: A Gene Cluster Encoding Rhizoxin Biosynthesis in “Burkholderia rhizoxina”, the Bacterial Endosymbiont of the Fungus Rhizopus microsporus (ChemBioChem 1/2007)
|
0
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0
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0
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0
|
29
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73
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0
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73
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20
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0
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0
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0
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0
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0
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Cover Picture: A Mass Spectrometric and Molecular Modelling Study of Cisplatin Binding to Transferrin (ChemBioChem 10/2005)
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0
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0
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0
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0
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5
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2
|
0
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2
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0
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0
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0
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0
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0
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0
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Cover Picture: A Mass Spectrometry Plate Reader: Monitoring Enzyme Activity and Inhibition with a Desorption/Ionization on Silicon (DIOS) Platform (ChemBioChem 7/2004)
|
0
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0
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0
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0
|
1
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0
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0
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0
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0
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0
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0
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0
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0
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0
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|
Cover Picture: A New Chemical Probe for Proteomics of Carbohydrate-Binding Proteins (ChemBioChem 2/2005)
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0
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0
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0
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0
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1
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4
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0
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4
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0
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0
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0
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0
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0
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0
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Cover Picture: A Novel Mycolactone from a Clinical Isolate of Mycobacterium ulcerans Provides Evidence for Additional Toxin Heterogeneity as a Result of Specific Changes in the Modular Polyketide Synthase (ChemBioChem 4/2005)
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0
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0
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0
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0
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1
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4
|
0
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4
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0
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0
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0
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0
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0
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0
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Cover Picture: A Powerful Combinatorial Screen to Identify High-Affinity Terbium(III)-Binding Peptides (ChemBioChem 4/2003)
|
0
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0
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0
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0
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3
|
1
|
0
|
1
|
0
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0
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0
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0
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0
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0
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Cover Picture: A Structure-Activity Guided Strategy for Fluorescent Labeling of Annonaceous Acetogenin Mimetics and their Application in Cell Biology (ChemBioChem 2/2007)
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0
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0
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0
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0
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41
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121
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0
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121
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30
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0
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0
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0
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0
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Cover Picture: ChemBioChem 1/2003
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0
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0
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0
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0
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6
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4
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0
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4
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Cover Picture: ChemBioChem 10/2002
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Cover Picture: ChemBioChem 11/2002
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Cover Picture: ChemBioChem 12/2002
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Cover Picture: ChemBioChem 4/2002
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Cover Picture: ChemBioChem 5/2002
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Cover Picture: ChemBioChem 6/2002
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Cover Picture: ChemBioChem 7/2002
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Cover Picture: ChemBioChem 8/2002
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Cover Picture: ChemBioChem 9/2002
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Cover Picture: Chemical Restriction: Strand Cleavage by Ammonia Treatment at 8Oxoguanine Yields Biologically Active DNA (ChemBioChem 7/2003)
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Cover Picture: Consensus Design of Repeat Proteins (ChemBioChem 2/2004)
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Cover Picture: DDI-μFIA - A Readily Configurable Microarray-Fluorescence Immunoassay Based on DNA-Directed Immobilization of Proteins (ChemBioChem 4/2004)
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Cover Picture: DNA Mismatch-Specific Base Flipping by a Bisacridine Macrocycle (ChemBioChem 12/2003)
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Cover Picture: Dendritic Polyamines: Simple Access to New Materials with Defined Treelike Structures for Application in Nonviral Gene Delivery (ChemBioChem 8/2004)
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Cover Picture: Design, Synthesis, and Preliminary Biological Evaluation of a DNA Methyltransferase-Directed Alkylating Agent (ChemBioChem 2/2006)
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Cover Picture: Detection of mRNA in Mammalian Cells with a Split Ribozyme Reporter (ChemBioChem 6/2006)
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Cover Picture: Differential Protein Assembly on Micropatterned Surfaces with Tailored Molecular and Surface Multivalency (ChemBioChem 9/2006)
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Cover Picture: Direct Evaluation of a Kinetic Model for RecA-Mediated DNA-strand exchange: The Importance of Nucleic Acid Dynamics and Entropy During Homologous Genetic Recombination (ChemBioChem 8/2006)
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Cover Picture: Direct Visualization of DNA Duplex Formation on the Surface of a Giant Liposome (ChemBioChem 8/2003)
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Cover Picture: Dynamics-Based Amplification of RNA Function and Its Characterization by Using NMR Spectroscopy (ChemBioChem 9/2005)
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Cover Picture: Enzymatic Fluorination in Streptomyces cattleya Takes Place with an Inversion of Configuration Consistent with an SN2 Reaction Mechanism (ChemBioChem 5/2004)
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11
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Cover Picture: Exploiting the Substrate Tolerance of Farnesyltransferase for Site-Selective Protein Derivatization (ChemBioChem 4/2007)
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Cover Picture: Fluorescence-Based Cloning of a Protein Tyrosine Kinase with a Yeast Tribrid System (ChemBioChem 8/2005)
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5
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Cover Picture: Forced Intercalation Probes (FIT Probes): Thiazole Orange as a Fluorescent Base in Peptide Nucleic Acids for Homogeneous Single-Nucleotide-Polymorphism Detection (ChemBioChem 1/2005)
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23
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Cover Picture: Hierarchical Mechanochemical Switches in Angiostatin (ChemBioChem 11/2006)
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Cover Picture: Identification by 19F NMR of Traditional Chinese Medicinal Plants Possessing Prolyl Oligopeptidase Inhibitory Activity (ChemBioChem 5/2006)
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Cover Picture: Identification of Labile UDP-Ketosugars in Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa: Key Metabolites used to make Glycan Virulence Factors (ChemBioChem 12/2006)
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Cover Picture: Light-Induced Formation of G-Quadruplex DNA Secondary Structures (ChemBioChem 11/2005)
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Cover Picture: Locked Nucleic Acids and Intercalating Nucleic Acids in the Design of Easily Denaturing Nucleic Acids: Thermal Stability Studies (ChemBioChem 12/2004)
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Cover Picture: NMR Structural Model of the Interaction of Herbicides with the Photosynthetic Reaction Center from Rhodobacter sphaeroides (ChemBioChem 9/2004)
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Cover Picture: NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein (ChemBioChem 2-3/2003)
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Cover Picture: Oligoribonucleotide Analogues Containing a Mixed Backbone of Phosphodiester and Formacetal Internucleoside Linkages, Together with Vicinal 2′-O-Methyl Groups (ChemBioChem 5/2007)
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63
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Cover Picture: On-Bead Chemical Synthesis and Display of Phosphopeptides for Affinity Pull-Down Proteomics (ChemBioChem 4/2006)
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Cover Picture: Phospholipases and Galactolipases Trigger Oxylipin-Mediated Wound-Activated Defence in the Red Alga Gracilaria chilensis against Epiphytes / Chloroplastic Glycolipids Fuel Aldehyde Biosynthesis in the Marine Diatom Thalassiosira r
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Cover Picture: Photoactivation of an Inhibitor of the 12/15-Lipoxygenase Pathway (ChemBioChem 7/2006)
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Cover Picture: Protein-Detecting Microarrays: Current Accomplishments and Requirements (ChemBioChem 5/2005)
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Cover Picture: Quantum Dots Protected with Tiopronin: A New Fluorescence System for Cell-Biology Studies (ChemBioChem 6/2005)
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Cover Picture: Regioselective Carbon-Carbon Bond Formation in Proteins with Palladium Catalysis; New Protein Chemistry by Organometallic Chemistry (ChemBioChem 1/2006)
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Cover Picture: Selective Protein Degradation by Ligand-Targeted Enzymes: Towards the Creation of Catalytic Antagonists (ChemBioChem 6/2003)
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Cover Picture: Semisynthesis and Characterization of the First Analogues of Pro-Neuropeptide Y (ChemBioChem 5/2003)
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Cover Picture: Sequence-Specific DNA Recognition by Monomeric bZIP Basic Regions Equipped with a Tripyrrole Unit on the N-Terminal Side. Towards the Development of Synthetic Mimics of Skn-1 (ChemBioChem 12/2005)
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Cover Picture: Site-Specific Modification of Epstein-Barr Virus-Encoded RNA 1 with N2-Benzylguanosine Limits the Binding Sites Occupied by PKR (ChemBioChem 3/2004)
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Cover Picture: Solution Structure of Domain 6 from a Self-Splicing Group II Intron Ribozyme: A Mg2+ Binding Site is Located Close to the Stacked Branch Adenosine (ChemBioChem 3/2007)
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59
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89
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26
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Cover Picture: Synthesis and Degradation of Nucleobases and Nucleic Acids by Formamide in the Presence of Montmorillonites (ChemBioChem 11/2004)
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Cover Picture: Synthesis of a 13C-Methyl-Group-Labeled Methionine Precursor as a Useful Tool for Simplifying Protein Structural Analysis by NMR Spectroscopy (ChemBioChem 6/2007)
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35
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Cover Picture: Targeting RNA with Small Molecules (ChemBioChem 10/2003)
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Cover Picture: The Activation of Fibroblast Growth Factors (FGFs) by Glycosaminoglycans: Influence of the Sulfation Pattern on the Biological Activity of FGF-1 (ChemBioChem 1/2004)
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7
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Cover Picture: The Molecular Mechanism of the Termination of Insect Diapause, Part 1: A Timer Protein, TIME-EA4, in the Diapause Eggs of the Silkworm Bombyx mori is a Metallo-Glycoprotein (ChemBioChem 10/2006)
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6
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Cover Picture: The Target Discovery Process (ChemBioChem 3/2005)
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Cover Picture: Tools for Glycomics: Mapping Interactions of Carbohydrates in Biological Systems (ChemBioChem 10/2004)
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7
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Cover Picture: Two-Dimensional Multiarray Formation of Hepatocyte Spheroids on a Microfabricated PEG-Brush Surface (ChemBioChem 6/2004)
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6
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5
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Creating Space for Large Secondary Alcohols by Rational Redesign of Candida antarctica Lipase B
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47
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Cryophotolysis of ortho-Nitrobenzyl Derivatives of Enzyme Ligands for the Potential Kinetic Crystallography of Macromolecules
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8
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Cryoprotection with L- and meso-Trehalose: Stereochemical Implications
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0
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28
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24
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Crystal Structure of Rhodopsin: A G-Protein-Coupled Receptor
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Crystal Structure of a Synthetic Cyclodecapeptide for Template-Assembled Synthetic Protein Design
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18
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1
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14
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Crystal Structures of Orotidine Monophosphate Decarboxylase: Does the Structure Reveal the Mechanism of Nature's Most Proficient Enzyme?
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0
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0
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Crystallographic Evidence for Isomeric Chromophores in 3-Fluorotyrosyl-Green Fluorescent Protein
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Cyberpills
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Cyclin Dependent Kinases and Cell Cycle Control (Nobel Lecture)
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0
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88
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11
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Cyclopropane Fatty Acid Synthase from Escherichia coli: Enzyme Purification and Inhibition by Vinylfluorine and Epoxide-Containing Substrate Analogues
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0
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0
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0
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0
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15
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2
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10
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Cysteine-Specific, Covalent Anchoring of Transition Organometallic Complexes to the Protein Papain from Carica papaya
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0
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0
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0
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92
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149
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173
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Cytochrome c Oxidase and the Regulation of Oxidative Phosphorylation
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0
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0
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75
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51
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8
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Cytosine Detection by a Fluorescein-Labeled Probe Containing Base-Discriminating Fluorescent Nucleobase
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0
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0
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0
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22
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1
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12
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2
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Cytostatic Activity of 1,10-Phenanthroline Derivatives Generated by the Clip-Phen Strategy
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0
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0
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0
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18
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6
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6
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DDI-μFIA - A Readily Configurable Microarray-Fluorescence Immunoassay Based on DNA-Directed Immobilization of Proteins
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0
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33
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DMACM-Caged Adenosine Nucleotides: Ultrafast Phototriggers for ATP, ADP, and AMP Activated by Long-Wavelength Irradiation
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0
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0
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0
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44
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4
|
0
|
0
|
0
|
0
|
0
|
|
DNA Catalysis: Potential, Limitations, Open Questions
|
0
|
0
|
0
|
0
|
48
|
32
|
3
|
35
|
3
|
0
|
0
|
0
|
0
|
0
|
|
DNA Compaction by Divalent Cations: Structural Specificity Revealed by the Potentiality of Designed Quaternary Diammonium Salts
|
0
|
0
|
0
|
0
|
9
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
DNA Damage Recognition. Edited by Wolfram Siede, Yoke Wah Kow and Paul W. Doetsch.
|
0
|
0
|
0
|
0
|
10
|
7
|
3
|
10
|
1
|
0
|
0
|
0
|
0
|
0
|
|
DNA Interstrand Cross-Linking Efficiency and Cytotoxic Activity of Novel Cadmium(ii)-Thiocarbodiazone Complexes
|
0
|
0
|
0
|
0
|
12
|
4
|
1
|
5
|
2
|
0
|
0
|
0
|
0
|
0
|
|
DNA Interstrand Crosslinks: Natural and Drug-Induced DNA Adducts that Induce Unique Cellular Responses
|
0
|
0
|
0
|
0
|
42
|
23
|
7
|
30
|
11
|
0
|
0
|
0
|
0
|
0
|
|
DNA Mismatch-Specific Base Flipping by a Bisacridine Macrocycle
|
0
|
0
|
0
|
0
|
12
|
12
|
0
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
DNA Technology: The Awesome Skill I. Edward Alcamo
|
0
|
0
|
0
|
0
|
3
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
DNA with γ-Aminopropyltriethoxysilane Switches between B- and C-Form Structures under Thermal Control
|
0
|
0
|
0
|
0
|
16
|
5
|
1
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
DNA-Directed Assembly of Bienzymic Complexes from In Vivo Biotinylated NAD(P)H:FMN Oxidoreductase and Luciferase
|
0
|
0
|
0
|
0
|
16
|
16
|
1
|
17
|
1
|
0
|
0
|
0
|
0
|
0
|
|
DNA-Templated Synthesis in Organic Solvents
|
0
|
0
|
0
|
0
|
98
|
72
|
17
|
89
|
7
|
0
|
0
|
0
|
0
|
0
|
|
De Novo Design, Synthesis, and In Vitro Evaluation of Inhibitors for Prokaryotic tRNA-Guanine Transglycosylase: A Dramatic Sulfur Effect on Binding Affinity
|
0
|
0
|
0
|
0
|
22
|
10
|
5
|
15
|
2
|
0
|
0
|
0
|
0
|
0
|
|
De Novo Design, Synthesis, and In Vitro Evaluation of a New Class of Nonpeptidic Inhibitors of the Malarial Enzyme Plasmepsin II
|
0
|
0
|
0
|
0
|
14
|
7
|
0
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Deciphering the Biosynthesis Pathway of the Antitumor Thiocoraline from a Marine Actinomycete and Its Expression in Two Streptomyces Species
|
0
|
0
|
0
|
0
|
76
|
45
|
11
|
56
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Deciphering the Biosynthetic Codes for the Potent Anti-SARS-CoV Cyclodepsipeptide Valinomycin in Streptomyces tsusimaensis ATCC 15141
|
0
|
0
|
0
|
0
|
44
|
14
|
4
|
18
|
16
|
0
|
0
|
0
|
0
|
0
|
|
Dendrimer-Activated Solid Supports for Nucleic Acid and Protein Microarrays
|
0
|
0
|
0
|
0
|
48
|
60
|
5
|
65
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Dendritic Catanionic Assemblies: In vitro Anti-HIV Activity of Phosphorus-Containing Dendrimers Bearing Galβ1cer Analogues
|
0
|
0
|
0
|
0
|
33
|
23
|
0
|
23
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Dendritic Polyamines: Simple Access to New Materials with Defined Treelike Structures for Application in Nonviral Gene Delivery
|
0
|
0
|
0
|
0
|
39
|
48
|
2
|
50
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Dependence of Concanavalin A Binding on Anomeric Configuration, Linkage Type, and Ligand Multiplicity for Thiourea-Bridged Mannopyranosyl-β-Cyclodextrin Conjugates
|
0
|
0
|
0
|
0
|
24
|
23
|
1
|
24
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Design In Silico, Synthesis and Binding Evaluation of a Carbohydrate-Based Scaffold for Structurally Novel Inhibitors of Matrix Metalloproteinases
|
0
|
0
|
0
|
0
|
10
|
6
|
1
|
7
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Design and Characterisation of an Artificial DNA-Binding Cytochrome
|
0
|
0
|
0
|
0
|
15
|
7
|
0
|
7
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli
|
0
|
0
|
0
|
0
|
26
|
18
|
4
|
22
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Design and Synthesis of Highly Potent and Selective Pharmacological Chaperones for the Treatment of Gaucher's disease
|
0
|
0
|
0
|
0
|
41
|
38
|
3
|
41
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Design and Synthesis of Oligosaccharides that Interfere with Glycoprotein Quality-control systems
|
0
|
0
|
0
|
0
|
29
|
12
|
0
|
12
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Design of a Composite Ethidium-Netropsin-Anilinoacridine Molecule for DNA Recognition
|
0
|
0
|
0
|
0
|
9
|
8
|
4
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Design of a Hairpin Polyamide, ZT65B, for Targeting the Inverted CCAAT Box (ICB) Site in the Multidrug Resistant (MDR1) Gene
|
0
|
0
|
0
|
0
|
20
|
11
|
8
|
19
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Design, Synthesis and Analysis of Inhibitors of Bacterial Aspartate Semialdehyde Dehydrogenase
|
0
|
0
|
0
|
0
|
49
|
22
|
3
|
25
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Design, Synthesis and Antimalarial Activity of Trifluoromethylartemisinin-Mefloquine Dual Molecules
|
0
|
0
|
0
|
0
|
40
|
22
|
4
|
26
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Design, Synthesis and Biological Evaluation of Sugar-Derived Ras Inhibitors
|
0
|
0
|
0
|
0
|
55
|
26
|
1
|
27
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Design, Synthesis, and Biological Evaluation of Aminoboronic Acids as Growth-Factor Receptor Inhibitors of EGFR and VEGFR-1 Tyrosine Kinases
|
0
|
0
|
0
|
0
|
58
|
20
|
3
|
23
|
14
|
0
|
1
|
0
|
0
|
0
|
|
Design, Synthesis, and Preliminary Biological Evaluation of a DNA Methyltransferase-Directed Alkylating Agent
|
0
|
0
|
0
|
0
|
32
|
30
|
2
|
32
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Designed Prostaglandins with Neurotrophic Activities
|
0
|
0
|
0
|
0
|
15
|
8
|
0
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Designing Fluorescent Sensors of Heparin
|
0
|
0
|
0
|
0
|
151
|
316
|
18
|
334
|
32
|
0
|
0
|
0
|
0
|
0
|
|
Destabilization of Quadruplex DNA by 8-Aminoguanine
|
0
|
0
|
0
|
0
|
17
|
17
|
2
|
19
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Detection of L-DNA-Tagged PCR Products by Surface Plasmon Resonance Imaging
|
0
|
0
|
0
|
0
|
78
|
159
|
12
|
171
|
18
|
0
|
0
|
0
|
0
|
0
|
|
Detection of Covalent Intermediates Formed in the Reaction of 4-Amino-4-deoxychorismate Synthase
|
0
|
0
|
0
|
0
|
10
|
8
|
0
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Detection of mRNA in Mammalian Cells with a Split Ribozyme Reporter
|
0
|
0
|
0
|
0
|
26
|
18
|
0
|
18
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Determination of the Carbon Kinetic Isotope Effects on Propane Hydroxylation Mediated by the Methane Monooxygenases from Methylococcus capsulatus (Bath) by Using Stable Carbon Isotopic Analysis
|
0
|
0
|
0
|
0
|
10
|
5
|
0
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Determination of the Conformation of the Human VDAC1 N-Terminal Peptide, a Protein Moiety Essential for the Functional Properties of the Pore
|
0
|
0
|
0
|
0
|
39
|
25
|
0
|
25
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Determination of the Cryptic Stereochemistry of the First PKS Chain-Extension Step in Ansamitocin Biosynthesis by Actinosynnema pretiosum
|
0
|
0
|
0
|
0
|
35
|
30
|
2
|
32
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Developing Promiscuous Glycosidases for Glycoside Synthesis: Residues W433 and E432 in Sulfolobus solfataricus β-Glycosidase are Important Glucoside- and Galactoside-Specificity Determinants
|
0
|
0
|
0
|
0
|
26
|
15
|
2
|
17
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Developing a Strategy for Activity-Based Detection of Enzymes in a Protein Microarray
|
0
|
0
|
0
|
0
|
33
|
27
|
6
|
33
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Development and Biological Evaluation of Potent and Specific Inhibitors of Mitotic Kinesin Eg5
|
0
|
0
|
0
|
0
|
52
|
32
|
8
|
40
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Development of Antiviral Fusion Inhibitors: Short Modified Peptides Derived from the Transmembrane Glycoprotein of Feline Immunodeficiency Virus
|
0
|
0
|
0
|
0
|
34
|
22
|
4
|
26
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Development of Novel 1,2,3,4-Tetrahydroisoquinoline Derivatives and Closely Related Compounds as Potent and Selective Dopamine D3 Receptor Ligands
|
0
|
0
|
0
|
0
|
114
|
63
|
2
|
65
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns
|
0
|
0
|
0
|
0
|
104
|
64
|
13
|
77
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Development of a Novel Chemical Probe for the Selective Enrichment of Phosphorylated Serine- and Threonine-Containing Peptides
|
0
|
0
|
0
|
0
|
68
|
60
|
9
|
69
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Development of a Working Model of the Active Site in Bovine Lens Leucine Aminopeptidase: A Density Functional Investigation
|
0
|
0
|
0
|
0
|
4
|
5
|
1
|
6
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Developments in the Characterisation of the Catalytic Triad of α-Chymotrypsin: Effect of the Protonation State of Asp102 on the 1H NMR Signals of His57
|
0
|
0
|
0
|
0
|
37
|
46
|
7
|
53
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Diatom/Copepod Interactions in Plankton: The Indirect Chemical Defense of Unicellular Algae
|
0
|
0
|
0
|
0
|
149
|
61
|
11
|
72
|
21
|
0
|
0
|
0
|
0
|
0
|
|
Dichlorination and Bromination of a Threonyl-S-Carrier Protein by the Non-heme FeII Halogenase SyrB2
|
0
|
0
|
0
|
0
|
41
|
30
|
1
|
31
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Dictionary of Bioinformatics and Computational Biology. Edited by John M. Hancock and Marketa J. Zvelebil.
|
0
|
0
|
0
|
0
|
4
|
0
|
0
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Diels-Alderases
|
0
|
0
|
0
|
0
|
41
|
29
|
3
|
32
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Different Roles of Electrostatics in Heat and in Cold: Adaptation by Citrate Synthase
|
0
|
0
|
0
|
0
|
41
|
24
|
2
|
26
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Differential Protein Assembly on Micropatterned Surfaces with Tailored Molecular and Surface Multivalency
|
0
|
0
|
0
|
0
|
56
|
57
|
3
|
60
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Diffusion NMR Spectroscopy: Folding and Aggregation of Domains in p53
|
0
|
0
|
0
|
0
|
45
|
34
|
6
|
40
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Dihydroimidazophenanthridinium (DIP)-Based DNA Binding Agents with Tuneable Structures and Biological Activity
|
0
|
0
|
0
|
0
|
40
|
31
|
3
|
34
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Dimedone Esters as Novel Hydrolase Substrates and their Application in the Colorimetric Detection of Lipase and Esterase Activity
|
0
|
0
|
0
|
0
|
17
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Direct Conversion of Ethane to Ethanol by Engineered Cytochrome P450 BM3
|
0
|
0
|
0
|
0
|
186
|
57
|
16
|
73
|
21
|
0
|
0
|
0
|
0
|
0
|
|
Direct Detection of a Specific Cellular mRNA on Functionalized Microplate
|
0
|
0
|
0
|
0
|
8
|
6
|
0
|
6
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Direct Evaluation of a Kinetic Model for RecA-Mediated DNA-strand exchange: The Importance of Nucleic Acid Dynamics and Entropy During Homologous Genetic Recombination
|
0
|
0
|
0
|
0
|
46
|
32
|
6
|
38
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Direct NMR-Spectroscopic Determination of Active-Enzyme Concentration by Titration with a Labeled Inhibitor: Determination of the kcat Value of Almond β-Glucosidase
|
0
|
0
|
0
|
0
|
13
|
13
|
0
|
13
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Direct Observation of Anion-Mediated Translocation of Fluorescent Oligoarginine Carriers into and across Bulk Liquid and Anionic Bilayer Membranes
|
0
|
0
|
0
|
0
|
33
|
21
|
2
|
23
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Direct Observations of the Cleavage Reaction of an L-DPPC Monolayer Catalyzed by Phospholipase A2 and Inhibited by an Indole Inhibitor at the Air/Water Interface
|
0
|
0
|
0
|
0
|
9
|
6
|
0
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Direct Quantitation of Poly(ADP-Ribose) Polymerase (PARP) Activity as a Means to Distinguish Necrotic and Apoptotic Death in Cell and Tissue Samples
|
0
|
0
|
0
|
0
|
19
|
14
|
2
|
16
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Direct Visualization of DNA Duplex Formation on the Surface of a Giant Liposome
|
0
|
0
|
0
|
0
|
24
|
21
|
1
|
22
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Direct Visualization of DNA Duplex Formation on the Surface of a Giant Liposome ()
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Directed DNA Polymerase Evolution: Effects of Mutations in Motif C on the Mismatch-Extension Selectivity of Thermus aquaticus DNA Polymerase
|
0
|
0
|
0
|
0
|
96
|
167
|
12
|
179
|
21
|
0
|
0
|
0
|
0
|
0
|
|
Directed Evolution of Bacillus subtilis Lipase A by Use of Enantiomeric Phosphonate Inhibitors: Crystal Structures and Phage Display Selection
|
0
|
0
|
0
|
0
|
65
|
63
|
6
|
69
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Directed Evolution of a Non-Heme-Iron-Dependent Extradiol Catechol Dioxygenase: Identification of Mutants with Intradiol Oxidative Cleavage Activity
|
0
|
0
|
0
|
0
|
60
|
54
|
8
|
62
|
3
|
0
|
1
|
0
|
0
|
0
|
|
Directed Evolution of an Amine Oxidase for the Preparative Deracemisation of Cyclic Secondary Amines
|
0
|
0
|
0
|
0
|
63
|
47
|
3
|
50
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Directed Evolution of an Esterase from Pseudomonas fluorescens Yields a Mutant with Excellent Enantioselectivity and Activity for the Kinetic Resolution of a Chiral Building Block
|
0
|
0
|
0
|
0
|
49
|
37
|
3
|
40
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Directing Flux in Glycan Biosynthetic Pathways with a Small Molecule Switch
|
0
|
0
|
0
|
0
|
18
|
15
|
2
|
17
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Disaccharide Mimetics of the Aminoglycoside Antibiotic Neamine
|
0
|
0
|
0
|
0
|
27
|
16
|
0
|
16
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Discovery of Complex Mixtures of Novel Long-Chain Quorum Sensing Signals in Free-Living and Host-Associated Marine Alphaproteobacteria
|
0
|
0
|
0
|
0
|
82
|
44
|
9
|
53
|
23
|
0
|
0
|
0
|
0
|
0
|
|
Discovery of Mycobacterium Tuberculosis Protein Tyrosine Phosphatase A (MptpA) Inhibitors Based on Natural Products and a Fragment-Based Approach
|
0
|
0
|
0
|
0
|
85
|
51
|
12
|
63
|
10
|
2
|
0
|
0
|
0
|
0
|
|
Discovery of Novel Antibacterial Agents Active Against Methicillin-Resistant Staphylococcus aureus from Combinatorial Benzopyran Libraries
|
0
|
0
|
0
|
0
|
19
|
17
|
1
|
18
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Discovery of Potent Inhibitors of PapG Adhesins from Uropathogenic Escherichia coli through Synthesis and Evaluation of Galabiose Derivatives
|
0
|
0
|
0
|
0
|
15
|
7
|
2
|
9
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Discovery of Superior Enzymes by Directed Molecular Evolution
|
0
|
0
|
0
|
0
|
49
|
32
|
7
|
39
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Discovery of a New Bacterial Polyketide Biosynthetic Pathway
|
0
|
0
|
0
|
0
|
62
|
35
|
4
|
39
|
22
|
0
|
0
|
0
|
0
|
0
|
|
Discrimination of Single-Nucleotide Alterations by G-Specific Fluorescence Quenching
|
0
|
0
|
0
|
0
|
16
|
13
|
0
|
13
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Dissecting the Streptavidin-Biotin Interaction by Phage-Displayed Shotgun Scanning
|
0
|
0
|
0
|
0
|
27
|
17
|
9
|
26
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Dissection of Conformationally Restricted Inhibitors Binding to a β-Glucosidase
|
0
|
0
|
0
|
0
|
42
|
19
|
2
|
21
|
8
|
2
|
0
|
0
|
0
|
0
|
|
Dissection of the Late Steps in Aureothin Biosynthesis
|
0
|
0
|
0
|
0
|
31
|
24
|
4
|
28
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Domain Reorientation and Induced Fit upon RNA Binding: Solution Structure and Dynamics of Ribosomal Protein L11 from Thermotoga maritima
|
0
|
0
|
0
|
0
|
26
|
14
|
7
|
21
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Domain-Selective Ligand-Binding Modes and Atomic Level Pharmacophore Refinement in Angiotensin I Converting Enzyme (ACE) Inhibitors
|
0
|
0
|
0
|
0
|
41
|
17
|
1
|
18
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Dopamine D3 Receptor Ligands with Antagonist Properties
|
0
|
0
|
0
|
0
|
28
|
14
|
0
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Droplets as Microreactors for High-Throughput Biology
|
0
|
0
|
0
|
0
|
153
|
248
|
22
|
270
|
34
|
1
|
0
|
0
|
0
|
0
|
|
Drug Design Strategies for Targeting G-Protein-Coupled Receptors
|
0
|
0
|
0
|
0
|
349
|
159
|
34
|
193
|
62
|
0
|
0
|
0
|
0
|
0
|
|
Drug Discovery Handbook. Edited by Shayne Cox Gad.
|
0
|
0
|
0
|
0
|
7
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Drug Identification through in vivo Screening of Chemical Libraries
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Drug Identification through in vivo Screening of Chemical Libraries
|
0
|
0
|
0
|
0
|
21
|
11
|
1
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Duplex RNA-Binding Enzymes: Headliners from Neurobiology, Virology, and Development
|
0
|
0
|
0
|
0
|
22
|
12
|
3
|
15
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Dynamic Chemical Instabilities in Living Cells May Provide a Novel Route in Drug Development
|
0
|
0
|
0
|
0
|
40
|
12
|
7
|
19
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Dynamic Deconvolution of a Pre-Equilibrated Dynamic Combinatorial Library of Acetylcholinesterase Inhibitors
|
0
|
0
|
0
|
0
|
26
|
26
|
1
|
27
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Dynamic Structural Investigations on the Torpedo Nicotinic Acetylcholine Receptor by Time-Resolved Photoaffinity Labeling
|
0
|
0
|
0
|
0
|
60
|
39
|
10
|
49
|
15
|
0
|
0
|
0
|
0
|
0
|
|
Dynamics in Rhodopsin
|
0
|
0
|
0
|
0
|
23
|
19
|
3
|
22
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Dynamics of Formation of a Helix-Turn-Helix Structure in a Membrane-Active Peptide: A Time-Resolved Spectroscopic Study
|
0
|
0
|
0
|
0
|
15
|
13
|
4
|
17
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Dynamics-Based Amplification of RNA Function and Its Characterization by Using NMR Spectroscopy
|
0
|
0
|
0
|
0
|
34
|
30
|
3
|
33
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Easy Access to (R,R)-3,4-Dihydroxy-3,4-dihydrobenzoic Acid with Engineered Strains of Escherichia coli
|
0
|
0
|
0
|
0
|
17
|
4
|
2
|
6
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: A Golden Future
|
0
|
0
|
0
|
0
|
2
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Closing the Gap between Chemistry and Biology
|
0
|
0
|
0
|
0
|
11
|
11
|
0
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Dissecting G-Protein-Coupled Receptors: Structure, Function, and Ligand Interaction
|
0
|
0
|
0
|
0
|
47
|
40
|
4
|
44
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Drug Discovery Process for Kinease Inhibitors
|
0
|
0
|
0
|
0
|
89
|
65
|
5
|
70
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Going Strong, Going Solo
|
0
|
0
|
0
|
0
|
3
|
2
|
1
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Interfaces...
|
0
|
0
|
0
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: NMR Spectroscopy of Biomacromolecules in Drug Discovery and Beyond
|
0
|
0
|
0
|
0
|
26
|
25
|
1
|
26
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Now we are 4
|
0
|
0
|
0
|
0
|
14
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Protein Design
|
0
|
0
|
0
|
0
|
16
|
7
|
0
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: RNA Targeting
|
0
|
0
|
0
|
0
|
12
|
4
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Through the Wire: Online Submission of Manuscripts
|
0
|
0
|
0
|
0
|
1
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Editorial: Unveiling the Mystery and Beauty of Organic Fluorine
|
0
|
0
|
0
|
0
|
21
|
30
|
0
|
30
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Effect of PbII on the Secondary Structure and Biological Activity of Trypsin
|
0
|
0
|
0
|
0
|
19
|
12
|
1
|
13
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Effect of Silver Nanoparticles on the Electron Transfer Reactivity and the Catalytic Activity of Myoglobin
|
0
|
0
|
0
|
0
|
29
|
22
|
3
|
25
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Effect of the Protein Matrix of Cytochrome c in Suppressing the Inherent Peroxidase Activity of Its Heme Prosthetic Group
|
0
|
0
|
0
|
0
|
3
|
3
|
2
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Effect of the Solvent on the Conformation of a Depsipeptide: NMR-Derived Solution Structure of Hormaomycin in DMSO from Residual Dipolar Couplings in a Novel DMSO-Compatible Alignment Medium
|
0
|
0
|
0
|
0
|
28
|
19
|
1
|
20
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Effects of Surface Charge on Denaturation of Bovine Carbonic Anhydrase
|
0
|
0
|
0
|
0
|
75
|
54
|
5
|
59
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Efficient Enzymatic Glycosylation of Peptides and Oligosaccharides from GalNAc and UTP
|
0
|
0
|
0
|
0
|
65
|
103
|
15
|
118
|
15
|
0
|
0
|
0
|
0
|
0
|
|
Efficient Sequence-Specific Purification of Listeria innocua mRNA Species by Triplex Affinity Capture with Parallel Tail-Clamps
|
0
|
0
|
0
|
0
|
20
|
11
|
1
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Eilatin Ru(II) Complexes Display Anti-HIV Activity and Enantiomeric Diversity in the Binding of RNA
|
0
|
0
|
0
|
0
|
16
|
12
|
0
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Elaboration of Neosamine Rings in the Biosynthesis of Neomycin and Butirosin
|
0
|
0
|
0
|
0
|
131
|
190
|
10
|
200
|
21
|
0
|
0
|
0
|
0
|
0
|
|
Electroactive Monolayer Substrates that Selectively Release Adherent Cells
|
0
|
0
|
0
|
0
|
25
|
14
|
4
|
18
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Electrochemical High-Content Screening of Nitric Oxide Release from Endothelial Cells
|
0
|
0
|
0
|
0
|
34
|
25
|
0
|
25
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Electronic Transduction of HIV-1 Drug Resistance in AIDS Patients
|
0
|
0
|
0
|
0
|
11
|
3
|
1
|
4
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Electrospray Ionization of a Whole Virus: Analyzing Mass, Structure, and Viability
|
0
|
0
|
0
|
0
|
22
|
17
|
5
|
22
|
2
|
0
|
1
|
0
|
0
|
0
|
|
Electrostatic Effects on the Thermodynamics of Protonation of Reduced Plastocyanin
|
0
|
0
|
0
|
0
|
16
|
4
|
0
|
4
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Elucidation of the Glycosylation Sequence of Mithramycin Biosynthesis: Isolation of 3A-Deolivosylpremithramycin B and Its Conversion to Premithramycin B by Glycosyltransferase MtmGII
|
0
|
0
|
0
|
0
|
11
|
6
|
1
|
7
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Enabling Glycosyltransferase Evolution: A Facile Substrate-Attachment Strategy for Phage-Display Enzyme Evolution
|
0
|
0
|
0
|
0
|
43
|
29
|
4
|
33
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Enantiocomplementary Enzymatic Resolution of the Chiral Auxiliary: cis,cis-6-(2,2-Dimethylpropanamido)spiro[4.4]nonan-1-ol and the Molecular Basis for the High Enantioselectivity of Subtilisin Carlsberg
|
0
|
0
|
0
|
0
|
13
|
8
|
0
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Enantiomeric 1,2,4-Trioxanes Display Equivalent in vitro Antimalarial Activity Versus Plasmodium falciparum Malaria Parasites: Implications for the Molecular Mechanism of Action of the Artemisinins
|
0
|
0
|
0
|
0
|
34
|
21
|
4
|
25
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Enantioselective Binding and Stable Encapsulation of α-Amino Acids in a Helical Poly(L-glutamic acid)-Shelled Dendrimer in Aqueous Solutions
|
0
|
0
|
0
|
0
|
23
|
15
|
1
|
16
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Encapsulation of Hemoglobin in Mesoporous Silica (FSM) - Enhanced Thermal Stability and Resistance to Denaturants
|
0
|
0
|
0
|
0
|
36
|
40
|
1
|
41
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Endohexosaminidase M: Exploring and Exploiting Enzyme Substrate Specificity
|
0
|
0
|
0
|
0
|
17
|
16
|
4
|
20
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Endosialidase NF Appears To Bind PolySia DP5 in a Helical Conformation
|
0
|
0
|
0
|
0
|
21
|
23
|
2
|
25
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Engineered Biosynthesis of Phenyl-Substituted Polyketides
|
0
|
0
|
0
|
0
|
13
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Engineered Ribozymes as Molecular Tools for Site-Specific Alteration of RNA Sequence
|
0
|
0
|
0
|
0
|
15
|
7
|
0
|
7
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Engineering Substrate Specificity of O6-Alkylguanine-DNA Alkyltransferase for Specific Protein Labeling in Living Cells
|
0
|
0
|
0
|
0
|
75
|
49
|
11
|
60
|
8
|
0
|
1
|
0
|
0
|
0
|
|
Engineering the Genetic Code: Expanding the Amino Acid Repertoire for the Design of Novel Proteins. By Nediljko Budisa.
|
0
|
0
|
0
|
0
|
1
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Enhanced Fructose Oxidase Activity in a Galactose Oxidase Variant
|
0
|
0
|
0
|
0
|
22
|
14
|
0
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Enhanced Inhibition of Transcription Start by Targeting with 2′-OMe Pentaribonucleotides Comprising Locked Nucleic Acids and Intercalating Nucleic Acids
|
0
|
0
|
0
|
0
|
10
|
4
|
0
|
4
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Enhancement of αPNA Binding Affinity and Specificity through Hydrophobic Interactions
|
0
|
0
|
0
|
0
|
2
|
1
|
1
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Enhancing Membrane Permeability by Fatty Acylation of Oligoarginine Peptides
|
0
|
0
|
0
|
0
|
31
|
17
|
2
|
19
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Entropically Assisted Carbohydrate Recognition by a Natural Killer Cell-Surface Receptor
|
0
|
0
|
0
|
0
|
9
|
5
|
1
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Enzymatic Cyclisation of Peptidomimetics with Incorporated (E)-Alkene Dipeptide Isosteres
|
0
|
0
|
0
|
0
|
21
|
8
|
1
|
9
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Enzymatic Fluorination in Streptomyces cattleya Takes Place with an Inversion of Configuration Consistent with an SN2 Reaction Mechanism
|
0
|
0
|
0
|
0
|
33
|
28
|
1
|
29
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Enzymatic Formation of Multiple Triterpenes by Mutation of Tyrosine 510 of the Oxidosqualene-Lanosterol Cyclase from Saccharomyces cerevisiae
|
0
|
0
|
0
|
0
|
17
|
8
|
2
|
10
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Enzymatic Incorporation of LNA Nucleotides into DNA Strands
|
0
|
0
|
0
|
0
|
102
|
173
|
13
|
186
|
20
|
0
|
0
|
0
|
0
|
0
|
|
Enzymatic Synthesis of Fluorescent Oligomers Assembled on a DNA Backbone
|
0
|
0
|
0
|
0
|
47
|
35
|
1
|
36
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Enzyme Assays: High-Throughput Screening, Genetic Selection and Fingerprinting. Edited by Jean-Louis Reymond.
|
0
|
0
|
0
|
0
|
7
|
11
|
0
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Enzymes for Peptide Cyclization
|
0
|
0
|
0
|
0
|
26
|
14
|
1
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
|
European Symposium of Bio-Organic Chemistry 2003 (ESBOC): The Evolution of Catalysis
|
0
|
0
|
0
|
0
|
8
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Evaluation of Bacterial RNase P RNA as a Drug Target
|
0
|
0
|
0
|
0
|
6
|
8
|
1
|
9
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Evaluation of Distance Metrics for Ligand-Based Similarity Searching
|
0
|
0
|
0
|
0
|
12
|
3
|
0
|
3
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Evaluation of Lipopolysaccharide Aggregation by Light Scattering Spectroscopy
|
0
|
0
|
0
|
0
|
24
|
12
|
1
|
13
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Evaluation of the Molecular Interactions of Fluorinated Amino Acids with Native Polypeptides
|
0
|
0
|
0
|
0
|
22
|
18
|
1
|
19
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Evidence for the Combined Participation of a C10 and a C15 Precursor in the Biosynthesis of Moenocinol, the Lipid Part of the Moenomycin Antibiotics
|
0
|
0
|
0
|
0
|
14
|
4
|
0
|
4
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Evidence for the Unusual Condensation of a Diketide with a Pentulose in the Methylenomycin Biosynthetic Pathway of Streptomyces coelicolor A3(2)
|
0
|
0
|
0
|
0
|
19
|
14
|
1
|
15
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Evidence that a Novel Thioesterase is Responsible for Polyketide Chain Release during Biosynthesis of the Polyether Ionophore Monensin
|
0
|
0
|
0
|
0
|
73
|
56
|
10
|
66
|
7
|
3
|
0
|
0
|
0
|
0
|
|
Evolution of Nitrate Reductase: Molecular and Structural Variations on a Common Function
|
0
|
0
|
0
|
0
|
58
|
33
|
3
|
36
|
15
|
0
|
0
|
0
|
0
|
0
|
|
Evolutionary Biology and Chemical Geology: A Timely Marriage
|
0
|
0
|
0
|
0
|
9
|
1
|
0
|
1
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Evolutions in Science Triggered by Green Fluorescent Protein (GFP)
|
0
|
0
|
0
|
0
|
144
|
81
|
23
|
104
|
26
|
1
|
0
|
0
|
0
|
0
|
|
Examining Reactivity and Specificity of Cytochrome c Peroxidase by using Combinatorial Mutagenesis
|
0
|
0
|
0
|
0
|
32
|
12
|
2
|
14
|
5
|
0
|
1
|
0
|
0
|
0
|
|
Examples of Peptide-Peptoid Hybrid Serine Protease Inhibitors Based on the Trypsin Inhibitor SFTI-1 with Complete Protease Resistance at the P1&bond;P1′ Reactive Site
|
0
|
0
|
0
|
0
|
19
|
15
|
1
|
16
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Exo-Mechanism Proximity-Accelerated Alkylations: Investigations of Linkers, Electrophiles and Surface Mutations in Engineered Cyclophilin-Cyclosporin Systems
|
0
|
0
|
0
|
0
|
26
|
21
|
3
|
24
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Expanding the Diversity of Unnatural Cell-Surface Sialic Acids
|
0
|
0
|
0
|
0
|
57
|
41
|
10
|
51
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Expanding the Genetic Code in a Mammalian Cell Line by the Introduction of Four-Base Codon/Anticodon Pairs
|
0
|
0
|
0
|
0
|
14
|
16
|
4
|
20
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Experimental Measurement of Noncovalent Interactions Between Halogens and Aromatic Rings
|
0
|
0
|
0
|
0
|
25
|
26
|
1
|
27
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Exploiting Conformationally Constrained Peptidomimetics and an Efficient Human-Compatible Delivery System in Synthetic Vaccine Design
|
0
|
0
|
0
|
0
|
18
|
10
|
1
|
11
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Exploiting Conformationally Constrained Peptidomimetics and an Efficient Human-Compatible Delivery System in Synthetic Vaccine Design
|
0
|
0
|
0
|
0
|
1
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Exploiting the Substrate Tolerance of Farnesyltransferase for Site-Selective Protein Derivatization
|
0
|
0
|
0
|
0
|
148
|
261
|
21
|
282
|
17
|
0
|
0
|
0
|
0
|
0
|
|
Exploring Hoogsteen and Reversed-Hoogsteen Duplex and Triplex Formation with Tricyclo-DNA Purine Sequences
|
0
|
0
|
0
|
0
|
56
|
27
|
7
|
34
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Exploring Protein-Protein Interactions with Phage Display
|
0
|
0
|
0
|
0
|
141
|
90
|
10
|
100
|
36
|
0
|
0
|
0
|
0
|
0
|
|
Exploring Recombinant Flavonoid Biosynthesis in Metabolically Engineered Escherichia coli
|
0
|
0
|
0
|
0
|
71
|
38
|
3
|
41
|
18
|
0
|
1
|
0
|
0
|
0
|
|
Exploring the Active-Site of a Rationally Redesigned Lipase for Catalysis of Michael-Type Additions
|
0
|
0
|
0
|
0
|
50
|
47
|
3
|
50
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Expression of Alternaria solani PKSF Generates a Set of Complex Reduced-Type Polyketides with Different Carbon-Lengths and Cyclization
|
0
|
0
|
0
|
0
|
36
|
19
|
1
|
20
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Extended Target Sequence Specificity of PNA-Minor-Groove Binder Conjugates
|
0
|
0
|
0
|
0
|
24
|
10
|
1
|
11
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Extending the Size of Protein-RNA Complexes Studied by Nuclear Magnetic Resonance Spectroscopy
|
0
|
0
|
0
|
0
|
39
|
23
|
7
|
30
|
9
|
0
|
0
|
0
|
0
|
0
|
|
External Regulation of Hairpin Ribozyme Activity by an Oligonucleotide Effector
|
0
|
0
|
0
|
0
|
3
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Extracellular Synthesis of Gold Nanoparticles by the Fungus Fusarium oxysporum
|
0
|
0
|
0
|
0
|
168
|
33
|
2
|
35
|
43
|
0
|
0
|
0
|
0
|
0
|
|
Facile Synthesis of 2,4-Dinitrophenyl α-D-Glycopyranosides as Chromogenic Substrates for α-Glycosidases
|
0
|
0
|
0
|
0
|
28
|
38
|
0
|
38
|
4
|
1
|
0
|
0
|
0
|
0
|
|
Factors Governing the Activity of Lyophilised and Immobilised Lipase Preparations in Organic Solvents
|
0
|
0
|
0
|
0
|
23
|
14
|
2
|
16
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Factors Mediating Activity, Selectivity, and Substrate Specificity for the Thiamin Diphosphate-Dependent Enzymes Benzaldehyde Lyase and Benzoylformate Decarboxylase
|
0
|
0
|
0
|
0
|
58
|
53
|
2
|
55
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Fast Detection of Single Nucleotide Polymorphisms (SNPs) by Primer Elongation with Monitoring of Supercritical-Angle Fluorescence
|
0
|
0
|
0
|
0
|
40
|
10
|
0
|
10
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Fast Directed Evolution of Non-Immunoglobulin Proteins by Somatic Hypermutation in Immune Cells
|
0
|
0
|
0
|
0
|
29
|
12
|
6
|
18
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Fatty Acid Hydroperoxide Lyase: A Plant Cytochrome P450 Enzyme Involved in Wound Healing and Pest Resistance
|
0
|
0
|
0
|
0
|
48
|
24
|
4
|
28
|
9
|
0
|
0
|
0
|
0
|
0
|
|
FenF: Servicing the Mycosubtilin Synthetase Assembly Line in trans
|
0
|
0
|
0
|
0
|
76
|
90
|
0
|
90
|
6
|
1
|
0
|
0
|
0
|
0
|
|
Firefly Luciferase Produces Hydrogen Peroxide as a Coproduct in Dehydroluciferyl Adenylate Formation
|
0
|
0
|
0
|
0
|
30
|
18
|
3
|
21
|
6
|
0
|
0
|
0
|
0
|
0
|
|
First Insight into the Symmetry and Flexibility of Membrane Efflux Pump P-Glycoprotein by Novel Bifunctional Modulators
|
0
|
0
|
0
|
0
|
16
|
10
|
0
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
First Synthesis of Heparan Sulfate Tetrasaccharides Containing both N-Acetylated and N-Unsubstituted Glucosamine - Search for Putative 10E4 Epitopes
|
0
|
0
|
0
|
0
|
59
|
74
|
9
|
83
|
18
|
0
|
0
|
0
|
0
|
0
|
|
Flexible Adaptations in the Structure of the tRNA-Modifying Enzyme tRNA-Guanine Transglycosylase and Their Implications for Substrate Selectivity, Reaction Mechanism and Structure-Based Drug Design
|
0
|
0
|
0
|
0
|
12
|
9
|
2
|
11
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescence Resonance Energy Transfer as a Probe for G-Quartet Formation by a Telomeric Repeat
|
0
|
0
|
0
|
0
|
43
|
40
|
6
|
46
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescence-Based Cloning of a Protein Tyrosine Kinase with a Yeast Tribrid System
|
0
|
0
|
0
|
0
|
21
|
15
|
5
|
20
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescent 5-Alkynyl-2′-Deoxyuridines: High Emission Efficiency of a Conjugated Perylene Nucleoside in a DNA Duplex
|
0
|
0
|
0
|
0
|
28
|
34
|
1
|
35
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescent Analysis of Translesion DNA Synthesis by Using a Novel, Non-natural Nucleotide Analogue
|
0
|
0
|
0
|
0
|
57
|
53
|
8
|
61
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescent Cellular Sensors of Steroid Receptor Ligands
|
0
|
0
|
0
|
0
|
25
|
12
|
2
|
14
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescent Detection of Apoptotic Cells by Using Zinc Coordination Complexes with a Selective Affinity for Membrane Surfaces Enriched with Phosphatidylserine
|
0
|
0
|
0
|
0
|
44
|
47
|
4
|
51
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescent Labelled Thiourea-Bridged Glycodendrons
|
0
|
0
|
0
|
0
|
17
|
9
|
0
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescent Multiplex Analysis of Carrier Protein Post-Translational Modification
|
0
|
0
|
0
|
0
|
22
|
9
|
1
|
10
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Fluorescent N2,N3-ϵ-Adenine Nucleoside and Nucleotide Probes: Synthesis, Spectroscopic Properties, and Biochemical Evaluation
|
0
|
0
|
0
|
0
|
25
|
27
|
3
|
30
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Fluorinated Phenylcyclopropylamines as Inhibitors of Monoamine Oxidases
|
0
|
0
|
0
|
0
|
13
|
4
|
0
|
4
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Fluorinated Protective Groups for On-Resin Quantification of Solid-Phase Oligosaccharide Synthesis with 19F NMR Spectroscopy
|
0
|
0
|
0
|
0
|
7
|
10
|
0
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Fluorine Interactions at the Thrombin Active Site: Protein Backbone Fragments H&bond;Cα&bond;C&dbond;O Comprise a Favorable C&bond;F Environment and Interactions of C&bond;F with Electrophiles
|
0
|
0
|
0
|
0
|
31
|
37
|
3
|
40
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Fluorine in Medicinal Chemistry
|
0
|
0
|
0
|
0
|
164
|
142
|
12
|
154
|
25
|
0
|
1
|
0
|
0
|
0
|
|
Folding and Activity of the Hammerhead Ribozyme
|
0
|
0
|
0
|
0
|
37
|
30
|
3
|
33
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Forced Intercalation Probes (FIT Probes): Thiazole Orange as a Fluorescent Base in Peptide Nucleic Acids for Homogeneous Single-Nucleotide-Polymorphism Detection
|
0
|
0
|
0
|
0
|
56
|
41
|
2
|
43
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Formation of DNA Triple Helices by an Oligonucleotide Conjugated to a Fluorescent Ruthenium Complex
|
0
|
0
|
0
|
0
|
21
|
13
|
3
|
16
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Formation of a Soluble Stable Complex between Pristine C60-Fullerene and a Native Blood Protein
|
0
|
0
|
0
|
0
|
100
|
68
|
12
|
80
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Formation of the Nonproteinogenic Amino Acid 2S,3R-Capreomycidine by VioD from the Viomycin Biosynthesis Pathway
|
0
|
0
|
0
|
0
|
15
|
13
|
1
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Free-Energy Simulations and Experiments Reveal Long-Range Electrostatic Interactions and Substrate-Assisted Specificity in an Aminoacyl-tRNA Synthetase
|
0
|
0
|
0
|
0
|
17
|
15
|
2
|
17
|
5
|
0
|
0
|
0
|
0
|
0
|
|
French Swimwear for Membrane Proteins
|
0
|
0
|
0
|
0
|
69
|
28
|
4
|
32
|
10
|
0
|
0
|
0
|
0
|
0
|
|
From RNAi to Epigenomes: How RNA Rules The World
|
0
|
0
|
0
|
0
|
32
|
18
|
1
|
19
|
3
|
0
|
0
|
0
|
0
|
0
|
|
From Virtual to Real Screening for D3 Dopamine Receptor Ligands
|
0
|
0
|
0
|
0
|
12
|
7
|
1
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
From the Insoluble Dye Indirubin towards Highly Active, Soluble CDK2-Inhibitors
|
0
|
0
|
0
|
0
|
63
|
70
|
12
|
82
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Function of lanGT3, a Glycosyltransferase Gene Involved in Landomycin A Biosynthesis
|
0
|
0
|
0
|
0
|
7
|
4
|
0
|
4
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Functional Analysis of the Aureothin Iterative Type I Polyketide Synthase
|
0
|
0
|
0
|
0
|
32
|
26
|
4
|
30
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Functional Antibody Arrays through Metal Ion-Affinity Templates
|
0
|
0
|
0
|
0
|
102
|
102
|
10
|
112
|
17
|
0
|
0
|
0
|
0
|
0
|
|
Functional Cell-Surface Display of a Lipase-Specific Chaperone
|
0
|
0
|
0
|
0
|
200
|
165
|
27
|
192
|
22
|
0
|
0
|
0
|
0
|
0
|
|
Functional Changes in the Family of Type 3 Copper Proteins During Evolution
|
0
|
0
|
0
|
0
|
27
|
11
|
3
|
14
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Functional Display of Active Bovine Adrenodoxin on the Surface of E. coli by Chemical Incorporation of the [2Fe-2S] Cluster
|
0
|
0
|
0
|
0
|
7
|
5
|
2
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Functional Evaluation of Carbohydrate-Centred Glycoclusters by Enzyme-Linked Lectin Assay: Ligands for Concanavalin A
|
0
|
0
|
0
|
0
|
40
|
25
|
1
|
26
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Functional Immobilization of a Ligand-Activated G-Protein-Coupled Receptor
|
0
|
0
|
0
|
0
|
30
|
25
|
2
|
27
|
52
|
0
|
0
|
1
|
0
|
0
|
|
Functional Immobilization of the Small GTPase Rab6A on DNA-Gold Nanoparticles by Using a Site-Specifically Attached Poly(ethylene glycol) Linker and Thiol Place-Exchange Reaction
|
0
|
0
|
0
|
0
|
86
|
135
|
19
|
154
|
14
|
0
|
1
|
0
|
0
|
0
|
|
Functional Mimicry of a Discontinuous Antigenic Site by a Designed Synthetic Peptide
|
0
|
0
|
0
|
0
|
8
|
6
|
2
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Functional Studies of Synthetic Gramicidin Hybrid Ion Channels in CHO Cells
|
0
|
0
|
0
|
0
|
46
|
57
|
3
|
60
|
6
|
0
|
1
|
0
|
0
|
0
|
|
Functionalizing Nanocrystalline Metal Oxide Electrodes With Robust Synthetic Redox Proteins
|
0
|
0
|
0
|
0
|
29
|
16
|
1
|
17
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Fungal Aerobic Reductive Dechlorination of Ethyl 2-Chloroacetoacetate by Saccharomyces cerevisiae: Mechanism of a Novel Type of Microbial Dehalogenation
|
0
|
0
|
0
|
0
|
34
|
9
|
0
|
9
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Fusarin C Biosynthesis in Fusarium moniliforme and Fusarium venenatum
|
0
|
0
|
0
|
0
|
48
|
28
|
6
|
34
|
5
|
0
|
0
|
0
|
0
|
0
|
|
G Quadruplex-Based FRET Probes with the Thrombin-Binding Aptamer (TBA) Sequence Designed for the Efficient Fluorometric Detection of the Potassium Ion
|
0
|
0
|
0
|
0
|
130
|
108
|
9
|
117
|
31
|
0
|
0
|
0
|
0
|
0
|
|
G-Protein Subunit Dissociation Is not an Integral Part of G-Protein Action
|
0
|
0
|
0
|
0
|
21
|
14
|
3
|
17
|
5
|
0
|
0
|
0
|
0
|
0
|
|
G-Protein-Coupled Receptor Microarrays
|
0
|
0
|
0
|
0
|
37
|
27
|
3
|
30
|
1
|
0
|
0
|
0
|
0
|
0
|
|
G-Protein-Coupled Receptors for Light: The Three-Dimensional Structure of Rhodopsin
|
0
|
0
|
0
|
0
|
17
|
10
|
2
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
GPCR Antitarget Modeling: Pharmacophore Models for Biogenic Amine Binding GPCRs to Avoid GPCR-Mediated Side Effects
|
0
|
0
|
0
|
0
|
75
|
41
|
10
|
51
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Gene Expression within Cell-Sized Lipid Vesicles
|
0
|
0
|
0
|
0
|
40
|
18
|
2
|
20
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Gene Therapy Needs Robust Synthetic Nonviral Platform Technologies
|
0
|
0
|
0
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Gene Therapy Needs Robust Synthetic Nonviral Platform Technologies
|
0
|
0
|
0
|
0
|
20
|
8
|
3
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Generation of New Landomycins with Altered Saccharide Patterns through Over-expression of the Glycosyltransferase Gene lanGT3 in the Biosynthetic Gene Cluster of Landomycin A in Streptomyces cyanogenus S-136
|
0
|
0
|
0
|
0
|
86
|
89
|
2
|
91
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Generation of Novel Landomycins M and O through Targeted Gene Disruption
|
0
|
0
|
0
|
0
|
17
|
12
|
0
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Genetic Control by Metabolite-Binding Riboswitches
|
0
|
0
|
0
|
0
|
197
|
118
|
27
|
145
|
43
|
0
|
0
|
0
|
0
|
0
|
|
Genetic Organization of the Biosynthetic Gene Cluster for the Antitumor Angucycline Oviedomycin in Streptomyces antibioticus ATCC 11891
|
0
|
0
|
0
|
0
|
31
|
13
|
4
|
17
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Genetic Targeting of Individual Cells with a Voltage-Sensitive Dye through Enzymatic Activation of Membrane Binding
|
0
|
0
|
0
|
0
|
41
|
18
|
0
|
18
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Geometrical trans Lipid Isomers: A New Target for Lipidomics
|
0
|
0
|
0
|
0
|
50
|
19
|
9
|
28
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Giant Vesicles as Microreactors for Enzymatic mRNA Synthesis
|
0
|
0
|
0
|
0
|
28
|
28
|
1
|
29
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Glycine Conjugates in a Lepidopteran Insect Herbivore - The Metabolism of Benzylglucosinolate in the Cabbage White Butterfly, Pieris rapae
|
0
|
0
|
0
|
0
|
40
|
39
|
4
|
43
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Glycopeptide Specificity of Helper T Cells Obtained in Mouse Models for Rheumatoid Arthritis
|
0
|
0
|
0
|
0
|
7
|
4
|
1
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Glycopeptide Synthesis and the Effects of Glycosylation on Protein Structure and Activity
|
0
|
0
|
0
|
0
|
68
|
41
|
1
|
42
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Gold Glyconanoparticles as New Tools in Antiadhesive Therapy
|
0
|
0
|
0
|
0
|
47
|
49
|
4
|
53
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Gold Glyconanoparticles as Probes to Explore the Carbohydrate-Mediated Self-Recognition of Marine Sponge Cells
|
0
|
0
|
0
|
0
|
32
|
24
|
8
|
32
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract
|
0
|
0
|
0
|
0
|
6
|
2
|
1
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract
|
0
|
0
|
0
|
0
|
3
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract
|
0
|
0
|
0
|
0
|
2
|
1
|
2
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract
|
0
|
0
|
0
|
0
|
8
|
4
|
2
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract
|
0
|
0
|
0
|
0
|
2
|
2
|
2
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract
|
0
|
0
|
0
|
0
|
3
|
1
|
1
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 1/2003
|
0
|
0
|
0
|
0
|
9
|
7
|
0
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 1/2004
|
0
|
0
|
0
|
0
|
10
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 1/2005
|
0
|
0
|
0
|
0
|
11
|
13
|
0
|
13
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 1/2006
|
0
|
0
|
0
|
0
|
7
|
7
|
0
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 1/2007
|
0
|
0
|
0
|
0
|
15
|
192
|
0
|
192
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 10/2002
|
0
|
0
|
0
|
0
|
13
|
8
|
4
|
12
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 10/2003
|
0
|
0
|
0
|
0
|
5
|
2
|
0
|
2
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 10/2004
|
0
|
0
|
0
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 10/2005
|
0
|
0
|
0
|
0
|
16
|
4
|
0
|
4
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 10/2006
|
0
|
0
|
0
|
0
|
4
|
21
|
0
|
21
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 11/2002
|
0
|
0
|
0
|
0
|
2
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 11/2003
|
0
|
0
|
0
|
0
|
8
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 11/2004
|
0
|
0
|
0
|
0
|
5
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 11/2005
|
0
|
0
|
0
|
0
|
6
|
4
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 11/2006
|
0
|
0
|
0
|
0
|
16
|
31
|
0
|
31
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 12/2002
|
0
|
0
|
0
|
0
|
4
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 12/2003
|
0
|
0
|
0
|
0
|
3
|
0
|
0
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 12/2004
|
0
|
0
|
0
|
0
|
1
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 12/2005
|
0
|
0
|
0
|
0
|
17
|
9
|
0
|
9
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 12/2006
|
0
|
0
|
0
|
0
|
4
|
65
|
0
|
65
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 2-3/2003
|
0
|
0
|
0
|
0
|
7
|
1
|
0
|
1
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 2/2004
|
0
|
0
|
0
|
0
|
4
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 2/2005
|
0
|
0
|
0
|
0
|
6
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 2/2006
|
0
|
0
|
0
|
0
|
14
|
5
|
0
|
5
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 2/2007
|
0
|
0
|
0
|
0
|
35
|
292
|
0
|
292
|
16
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 3/2004
|
0
|
0
|
0
|
0
|
5
|
1
|
0
|
1
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 3/2005
|
0
|
0
|
0
|
0
|
5
|
3
|
0
|
3
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 3/2006
|
0
|
0
|
0
|
0
|
8
|
6
|
0
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 3/2007
|
0
|
0
|
0
|
0
|
92
|
351
|
0
|
351
|
17
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 4/2002
|
0
|
0
|
0
|
0
|
7
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 4/2003
|
0
|
0
|
0
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 4/2004
|
0
|
0
|
0
|
0
|
44
|
3
|
0
|
3
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 4/2005
|
0
|
0
|
0
|
0
|
11
|
4
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 4/2006
|
0
|
0
|
0
|
0
|
6
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 4/2007
|
0
|
0
|
0
|
0
|
32
|
257
|
0
|
257
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Graphical Abstract: ChemBioChem 5/2002
|
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4
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Graphical Abstract: ChemBioChem 5/2003
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Graphical Abstract: ChemBioChem 5/2004
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11
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12
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Graphical Abstract: ChemBioChem 5/2005
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9
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5
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Graphical Abstract: ChemBioChem 5/2006
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Graphical Abstract: ChemBioChem 5/2007
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98
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277
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Graphical Abstract: ChemBioChem 6/2002
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Graphical Abstract: ChemBioChem 6/2003
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Graphical Abstract: ChemBioChem 6/2004
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9
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Graphical Abstract: ChemBioChem 6/2005
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Graphical Abstract: ChemBioChem 6/2006
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Graphical Abstract: ChemBioChem 6/2007
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60
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100
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Graphical Abstract: ChemBioChem 7/2002
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Graphical Abstract: ChemBioChem 7/2003
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Graphical Abstract: ChemBioChem 7/2004
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Graphical Abstract: ChemBioChem 7/2005
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6
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Graphical Abstract: ChemBioChem 7/2006
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7
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14
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14
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Graphical Abstract: ChemBioChem 8/2002
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7
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2
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Graphical Abstract: ChemBioChem 8/2003
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12
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3
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Graphical Abstract: ChemBioChem 8/2004
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9
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6
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Graphical Abstract: ChemBioChem 8/2005
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10
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3
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Graphical Abstract: ChemBioChem 8/2006
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6
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8
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8
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2
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Graphical Abstract: ChemBioChem 9/2002
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4
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1
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1
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Graphical Abstract: ChemBioChem 9/2003
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5
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1
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0
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1
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0
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Graphical Abstract: ChemBioChem 9/2004
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19
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5
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0
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5
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2
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Graphical Abstract: ChemBioChem 9/2005
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2
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1
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1
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Graphical Abstract: ChemBioChem 9/2006
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9
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17
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17
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1
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0
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0
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Guanine Oxidation by Electron Transfer: One- versus Two-Electron Oxidation Mechanism
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0
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0
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22
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15
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1
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16
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1
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0
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0
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0
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Guanine and Plasmid DNA binding of Mono- and Trinuclear fac-[Re(CO)3]+ Complexes with Amino Acid Ligands
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0
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0
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36
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20
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1
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21
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4
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0
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0
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0
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0
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0
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Guanine-Rich DNA Nanocircles for the Synthesis and Characterization of Long Cytosine-Rich Telomeric DNAs
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0
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0
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0
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0
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22
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13
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1
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14
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2
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0
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0
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|
Guide to Mutation Detection. Edited by Graham R. Taylor and Ian N. Day.
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0
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0
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0
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0
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2
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0
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0
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0
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0
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0
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0
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0
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0
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0
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|
Halogenated Veneers: Protein Cross-Linking and Halogenation in the Jaws of Nereis, a Marine Polychaete Worm
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0
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0
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0
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0
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22
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29
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2
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31
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1
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0
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0
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0
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0
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0
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Halogenation of Drugs Enhances Membrane Binding and Permeation
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0
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0
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0
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0
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30
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27
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4
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31
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1
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0
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1
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0
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0
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|
Handbook of ATPases - Biochemistry, Cell Biology, Pathophysiology. Edited by Masamitsu Futai, Yoh Wada and Jack H. Kaplan.
|
0
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0
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0
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0
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13
|
4
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0
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4
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5
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0
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0
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0
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0
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0
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|
Handbook of Biotransformations of Aromatic Compounds. By Brian L. Goodwin.
|
0
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0
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0
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0
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1
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0
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0
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0
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0
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0
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0
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0
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|
Handbook of Toxicogenomics: Strategies and Applications. Edited by Jürgen Borlak.
|
0
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0
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0
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0
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6
|
2
|
0
|
2
|
3
|
0
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0
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0
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0
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0
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|
Heme Alkylation by Artesunic Acid and Trioxaquine DU1301, Two Antimalarial Trioxanes
|
0
|
0
|
0
|
0
|
25
|
18
|
4
|
22
|
6
|
0
|
0
|
1
|
0
|
0
|
|
Heterogeneous Assembly of Complementary Peptide Pairs into Amyloid Fibrils with α-β Structural Transition
|
0
|
0
|
0
|
0
|
11
|
10
|
3
|
13
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Heteronuclear Multidimensional NMR Spectroscopy of Solubilized Membrane Proteins: Resonance Assignment of Native Bacteriorhodopsin
|
0
|
0
|
0
|
0
|
14
|
11
|
0
|
11
|
0
|
0
|
0
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0
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0
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0
|
|
Hierarchical Mechanochemical Switches in Angiostatin
|
0
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0
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0
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0
|
29
|
16
|
6
|
22
|
2
|
0
|
0
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0
|
0
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0
|
|
High-Content Screening and Profiling of Drug Activity in an Automated Centrosome-Duplication Assay
|
0
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0
|
0
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0
|
65
|
35
|
8
|
43
|
8
|
0
|
0
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0
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0
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0
|
|
High-Content Screening and Profiling of Drug Activity in an Automated Centrosome-Duplication Assay
|
0
|
0
|
0
|
0
|
1
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
High-Resolution Capillary Zone and Gel Electrophoresis of Structurally Similar Amphipathic Glutathione Conjugates Based on Interaction with β-Cyclodextrins
|
0
|
0
|
0
|
0
|
6
|
5
|
0
|
5
|
4
|
0
|
0
|
0
|
0
|
0
|
|
High-Resolution Solid-State NMR Studies on Uniformly [13C,15N]-Labeled Ubiquitin
|
0
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0
|
0
|
0
|
47
|
36
|
7
|
43
|
2
|
0
|
0
|
0
|
0
|
0
|
|
High-Throughput Evaluation of Antioxidant and Pro-oxidant Activities of Polyphenols with Thymidine Protection Assays
|
0
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0
|
0
|
0
|
33
|
8
|
1
|
9
|
3
|
0
|
0
|
0
|
0
|
0
|
|
High-Throughput Mass-Spectrometry Monitoring for Multisubstrate Enzymes: Determining the Kinetic Parameters and Catalytic Activities of Glycosyltransferases
|
0
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0
|
0
|
0
|
102
|
50
|
6
|
56
|
8
|
0
|
0
|
0
|
0
|
0
|
|
High-Throughput Screening for Kinase Inhibitors
|
0
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0
|
0
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0
|
192
|
114
|
7
|
121
|
28
|
0
|
2
|
0
|
0
|
0
|
|
High-Throughput Substrate Specificity Studies of Sialidases by Using Chemoenzymatically Synthesized Sialoside Libraries
|
0
|
0
|
0
|
0
|
104
|
162
|
14
|
176
|
11
|
0
|
1
|
0
|
0
|
0
|
|
High-Throughput-Compatible Assay for glmS Riboswitch Metabolite Dependence
|
0
|
0
|
0
|
0
|
55
|
50
|
6
|
56
|
8
|
0
|
0
|
1
|
0
|
0
|
|
Highlights in Bioorganic Chemistry. Edited by Carsten Schmuck and Helma Wennemers.
|
0
|
0
|
0
|
0
|
3
|
1
|
0
|
1
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Highly Efficient Chemoenzymatic Synthesis of Novel Branched Thiooligosaccharides by Substrate Direction with Glucansucrases
|
0
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0
|
0
|
0
|
136
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233
|
28
|
261
|
29
|
1
|
0
|
0
|
0
|
0
|
|
Highly Potent Vitamin D Receptor Antagonists: Design, Synthesis, and Biological Evaluation
|
0
|
0
|
0
|
0
|
52
|
39
|
1
|
40
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Highly Productive Autocondensation and Transglycosylation Reactions with Sulfolobus solfataricus Glycosynthase
|
0
|
0
|
0
|
0
|
15
|
6
|
0
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Highly Selective Glycosylated Prodrugs of Cytostatic CC-1065 Analogues for Antibody-Directed Enzyme Tumor Therapy
|
0
|
0
|
0
|
0
|
15
|
15
|
1
|
16
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Highly Stable DNA Triplexes Formed with Cationic Phosphoramidate Pyrimidine α-Oligonucleotides
|
0
|
0
|
0
|
0
|
15
|
9
|
1
|
10
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Histidine Residue at Position 234 of Oxidosqualene-Lanosterol Cyclase from Saccharomyces cerevisiae Simultaneously Influences Cyclization, Rearrangement, and Deprotonation Reactions
|
0
|
0
|
0
|
0
|
12
|
6
|
2
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Hoechst 33258 Selectively Inhibits Group I Intron Self-Splicing by Affecting RNA Folding
|
0
|
0
|
0
|
0
|
15
|
5
|
4
|
9
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Hoechst 33258 as a pH-Sensitive Probe to Study the Interaction of Amine Oxide Surfactants with DNA
|
0
|
0
|
0
|
0
|
19
|
7
|
1
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Homology Modeling and Molecular Dynamics Simulations of the Mu Opioid Receptor in a Membrane-Aqueous System
|
0
|
0
|
0
|
0
|
53
|
22
|
3
|
25
|
12
|
0
|
0
|
0
|
0
|
0
|
|
How Does DNA Compaction Favor Chiral Selectivity with Cationic Species? Higher Selectivity with Lower Cationic Charge
|
0
|
0
|
0
|
0
|
12
|
4
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
How Much NMR Data Is Required To Determine a Protein-Ligand Complex Structure?
|
0
|
0
|
0
|
0
|
77
|
47
|
8
|
55
|
9
|
0
|
0
|
0
|
0
|
0
|
|
How to Control NO Production in Cells: Nω,Nω-Dimethyl-L-Arginine Dimethylaminohydrolase as a Novel Drug Target
|
0
|
0
|
0
|
0
|
36
|
19
|
2
|
21
|
15
|
0
|
0
|
1
|
0
|
0
|
|
How to Prepare Membrane Proteins for Solid-State NMR: A Case Study on the α-Helical Integral Membrane Protein Diacylglycerol Kinase from E. coli
|
0
|
0
|
0
|
0
|
42
|
27
|
5
|
32
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Hydrogen-Bonding in 2-Aminobenzoyl-α-chymotrypsin Formed by Acylation of the Enzyme with Isatoic Anhydride: IR and Mass Spectroscopic Studies
|
0
|
0
|
0
|
0
|
5
|
2
|
1
|
3
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Hydrogenases: Hydrogen-Activating Enzymes
|
0
|
0
|
0
|
0
|
81
|
67
|
12
|
79
|
23
|
0
|
0
|
0
|
0
|
0
|
|
Hydrolases in Organic Synthesis: Regio- and Stereoselective Biotransformations. By Uwe T. Bornscheuer and Romas J. Kazlauskas.
|
0
|
0
|
0
|
0
|
7
|
10
|
3
|
13
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Hyrtiosal, a PTP1B Inhibitor from the Marine Sponge Hyrtios erectus, Shows Extensive Cellular Effects on PI3K/AKT Activation, Glucose Transport, and TGFβ/Smad2 Signaling
|
0
|
0
|
0
|
0
|
202
|
209
|
17
|
226
|
36
|
0
|
0
|
0
|
0
|
0
|
|
INDEX: ChemBioChem 2004
|
0
|
0
|
0
|
0
|
6
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Icosahedral Virus Particles as Polyvalent Carbohydrate Display Platforms
|
0
|
0
|
0
|
0
|
33
|
30
|
1
|
31
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Identification and Biosynthesis of an Aggregation Pheromone of the Storage Mite Chortoglyphus arcuatus
|
0
|
0
|
0
|
0
|
25
|
13
|
2
|
15
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Identification by 19F NMR of Traditional Chinese Medicinal Plants Possessing Prolyl Oligopeptidase Inhibitory Activity
|
0
|
0
|
0
|
0
|
34
|
16
|
2
|
18
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Identification of Labile UDP-Ketosugars in Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa: Key Metabolites used to make Glycan Virulence Factors
|
0
|
0
|
0
|
0
|
52
|
40
|
9
|
49
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Identification of Lipoxygenase Inhibitory Peptides from β-Casein by Using SPOT Synthesis
|
0
|
0
|
0
|
0
|
3
|
4
|
1
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Identification of Lipoxygenase Inhibitory Peptides from β-Casein by Using SPOT Synthesis
|
0
|
0
|
0
|
0
|
16
|
7
|
1
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Identification of Luciferyl Adenylate and Luciferyl Coenzyme A Synthesized by Firefly Luciferase
|
0
|
0
|
0
|
0
|
11
|
10
|
1
|
11
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Identification of New Acceptor Specificities of Glycosyltransferase R with the Aid of Substrate Microarrays
|
0
|
0
|
0
|
0
|
52
|
25
|
5
|
30
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Identification of Novel Anthrax Lethal Factor Inhibitors Generated by Combinatorial Pictet-Spengler Reaction Followed by Screening in situ
|
0
|
0
|
0
|
0
|
44
|
25
|
1
|
26
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Identification of Peptide Ligands for Target RNA Structures Derived from the HIV-1 Packaging Signal ψ by Screening Phage-Displayed Peptide Libraries
|
0
|
0
|
0
|
0
|
12
|
8
|
0
|
8
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Identification of a Deacetylase Involved in the Maturation of Teicoplanin
|
0
|
0
|
0
|
0
|
32
|
36
|
2
|
38
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Identification of a Phosphopantetheinyl Transferase for Erythromycin Biosynthesis in Saccharopolyspora erythraea
|
0
|
0
|
0
|
0
|
30
|
17
|
3
|
20
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Identification of the Cytochrome P450 Monooxygenase that Bridges the Clavine and Ergoline Alkaloid Pathways
|
0
|
0
|
0
|
0
|
45
|
33
|
3
|
36
|
11
|
4
|
0
|
0
|
0
|
0
|
|
Identification of the Luciferin-Luciferase System and Quantification of Coelenterazine by Mass Spectrometry in the Deep-Sea Luminous Ostracod Conchoecia pseudodiscophora
|
0
|
0
|
0
|
0
|
51
|
21
|
2
|
23
|
6
|
0
|
1
|
0
|
0
|
0
|
|
Imaging Activation of Two Ras Isoforms Simultaneously in a Single Cell
|
0
|
0
|
0
|
0
|
53
|
41
|
8
|
49
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Imaging of Selective Nuclear Receptor Modulator-Induced Conformational Changes in the Nuclear Receptor to Allow Interaction with Coactivator and Corepressor Proteins in Living Cells
|
0
|
0
|
0
|
0
|
18
|
28
|
0
|
28
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Imaging the Selective Binding of Synapsin to Anionic Membrane Domains
|
0
|
0
|
0
|
0
|
25
|
11
|
4
|
15
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Immuno-Carbon Nanotubes and Recognition of Pathogens
|
0
|
0
|
0
|
0
|
65
|
42
|
1
|
43
|
16
|
0
|
0
|
0
|
0
|
0
|
|
Immunological Optimization of a Generic Hydrophobic Pocket for High Affinity Hapten Binding and Diels-Alder Activity
|
0
|
0
|
0
|
0
|
15
|
6
|
1
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Impact of Epimerization Domains on the Intermodular Transfer of Enzyme-Bound Intermediates in Nonribosomal Peptide Synthesis
|
0
|
0
|
0
|
0
|
62
|
48
|
1
|
49
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Impact of the Guanidinium Group on Hybridization and Cellular Uptake of Cationic Oligonucleotides
|
0
|
0
|
0
|
0
|
54
|
38
|
2
|
40
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Improved Cell Viability of Linear Polyethylenimine through γ-Cyclodextrin Inclusion for Effective Gene Delivery
|
0
|
0
|
0
|
0
|
50
|
32
|
2
|
34
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Improved Enantioselectivity of a Lipase by Rational Protein Engineering
|
0
|
0
|
0
|
0
|
47
|
25
|
2
|
27
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Improvement of Hepatocyte-Specific Gene Expression by a Targeted Colchicine Prodrug
|
0
|
0
|
0
|
0
|
8
|
4
|
0
|
4
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Improving Escherichia coli Alkaline Phosphatase Efficacy by Additional Mutations inside and outside the Catalytic Pocket
|
0
|
0
|
0
|
0
|
37
|
15
|
1
|
16
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Improving Antisense Oligonucleotide Binding to Human Serum Albumin: Dramatic Effect of Ibuprofen Conjugation
|
0
|
0
|
0
|
0
|
5
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
In Situ Fabrication of Cross-Linked Protein Membranes by Using Microfluidics
|
0
|
0
|
0
|
0
|
68
|
49
|
3
|
52
|
1
|
0
|
0
|
0
|
0
|
0
|
|
In Situ Generation and Screening of a Dynamic Combinatorial Carbohydrate Library against Concanavalin A
|
0
|
0
|
0
|
0
|
27
|
41
|
0
|
41
|
6
|
0
|
0
|
0
|
0
|
0
|
|
In Vitro Inhibition of Human Immunodeficiency Virus Type-1 (HIV-1) Reverse Transcriptase by Gold(III) Porphyrins
|
0
|
0
|
0
|
0
|
26
|
12
|
0
|
12
|
4
|
0
|
0
|
0
|
0
|
0
|
|
In Vitro Selection of Hammerhead Ribozyme Sequence Variants
|
0
|
0
|
0
|
0
|
11
|
6
|
2
|
8
|
4
|
0
|
0
|
0
|
0
|
0
|
|
In Vitro Selection of N-Peptide-Binding RNA on a Quartz-Crystal Microbalance to Study a Sequence-Specific Interaction between the Peptide and Loop RNA
|
0
|
0
|
0
|
0
|
6
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
In Vitro and In Vivo Ligand Binding to the 5HT3 Serotonin Receptor Characterised by Time-Resolved Fluorescence Spectroscopy
|
0
|
0
|
0
|
0
|
28
|
10
|
2
|
12
|
8
|
0
|
0
|
0
|
0
|
0
|
|
In Vivo Chaperone-Assisted Folding of α-1,6-Fucosyltransferase from Rhizobium sp.
|
0
|
0
|
0
|
0
|
9
|
6
|
1
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
In Vivo Characterization of Tandem C-Terminal Thioesterase Domains in Arthrofactin Synthetase
|
0
|
0
|
0
|
0
|
105
|
124
|
6
|
130
|
17
|
0
|
0
|
0
|
0
|
0
|
|
In Vivo Oxo Transfer: Reactions of Native and W-Substituted Dimethyl Sulfoxide Reductase Monitored by 1H NMR Spectroscopy
|
0
|
0
|
0
|
0
|
13
|
5
|
1
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
In Vivo Photocrosslinking with Unnatural Amino Acid Mutagenesis
|
0
|
0
|
0
|
0
|
102
|
70
|
18
|
88
|
17
|
0
|
0
|
0
|
0
|
0
|
|
In-Cell NMR Spectroscopy
|
0
|
0
|
0
|
0
|
52
|
50
|
4
|
54
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Inactivation of gilGT, Encoding a C-Glycosyltransferase, and gilOIII, Encoding a P450 Enzyme, Allows the Details of the Late Biosynthetic Pathway to Gilvocarcin V to be Delineated
|
0
|
0
|
0
|
0
|
34
|
18
|
1
|
19
|
4
|
0
|
1
|
0
|
0
|
0
|
|
Incorporation of Unnatural Amino Acids into Cytochrome c3 and Specific Viologen Binding to the Unnatural Amino Acid
|
0
|
0
|
0
|
0
|
59
|
56
|
5
|
61
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Increased Single-Nucleotide Discrimination of PCR by Primer Probes Bearing Hydrophobic 4′C Modifications
|
0
|
0
|
0
|
0
|
24
|
7
|
0
|
7
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Increased Thermal Stability of Site-Selectively Glycosylated Dihydrofolate Reductase
|
0
|
0
|
0
|
0
|
11
|
5
|
0
|
5
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Indolo[2,3-b]-Quinolizinium Bromide: An Efficient Intercalator with DNA-Photodamaging Properties
|
0
|
0
|
0
|
0
|
14
|
8
|
1
|
9
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Indolocarbazole Glycosides in Inactive Conformations
|
0
|
0
|
0
|
0
|
15
|
10
|
4
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Induction of Cell Death of Gastric Cancer Cells by a Modified Compound of the Annonaceous Acetogenin Family
|
0
|
0
|
0
|
0
|
28
|
10
|
1
|
11
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Induction of DNA-Double-Strand Breaks by Auger Electrons from 99mTc Complexes with DNA-Binding Ligands
|
0
|
0
|
0
|
0
|
47
|
39
|
3
|
42
|
9
|
0
|
1
|
0
|
0
|
0
|
|
Influence of Serine O-Glycosylation or O-Phoshorylation Close to the vJun Nuclear Localisation Sequence on Nuclear Import
|
0
|
0
|
0
|
0
|
39
|
28
|
1
|
29
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Inhibition Studies of Porphobilinogen Synthase from Escherichia coli Differentiating between the Two Recognition Sites
|
0
|
0
|
0
|
0
|
23
|
8
|
3
|
11
|
2
|
0
|
1
|
0
|
0
|
0
|
|
Inhibition and Detection of Galectins
|
0
|
0
|
0
|
0
|
169
|
96
|
17
|
113
|
23
|
1
|
0
|
0
|
0
|
0
|
|
Inhibition of β-Amyloid Aggregation and Neurotoxicity by Complementary (Antisense) Peptides
|
0
|
0
|
0
|
0
|
15
|
9
|
4
|
13
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Inhibition of Adhesion of Type 1 Fimbriated Escherichia coli to Highly Mannosylated Ligands
|
0
|
0
|
0
|
0
|
33
|
21
|
3
|
24
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Inhibition of Angiogenesis-Relevant Receptor Tyrosine Kinases by Sulindac Analogues
|
0
|
0
|
0
|
0
|
11
|
18
|
3
|
21
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Inhibition of Fibril Formation of Aβ by Guanidiniocarbonyl Pyrrole Receptors
|
0
|
0
|
0
|
0
|
27
|
15
|
4
|
19
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Inhibition of Golgi Mannosidase II with Mannostatin A Analogues: Synthesis, Biological Evaluation, and Structure-Activity Relationship Studies
|
0
|
0
|
0
|
0
|
39
|
27
|
2
|
29
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Inhibitor and Protein Microarrays for Activity-Based Recognition of Lipolytic Enzymes
|
0
|
0
|
0
|
0
|
9
|
12
|
0
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Inhibitor and Protein Microarrays for Activity-Based Recognition of Lipolytic Enzymes
|
0
|
0
|
0
|
0
|
40
|
34
|
3
|
37
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Integrating Input from Multiple Signals: The VirA/VirG Two-Component System of Agrobacterium tumefaciens
|
0
|
0
|
0
|
0
|
31
|
11
|
4
|
15
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Integrin α5β1 Ligands: Biological Evaluation and Conformational Analysis
|
0
|
0
|
0
|
0
|
26
|
17
|
2
|
19
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Interaction of the Catalytic Domain of Inositol 1,4,5-Trisphosphate 3-Kinase A with Inositol Phosphate Analogues
|
0
|
0
|
0
|
0
|
31
|
21
|
0
|
21
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Intracellular Delivery of Bioactive Peptides to RBL-2H3 Cells Induces β-Hexosaminidase Secretion and Phospholipase D Activation
|
0
|
0
|
0
|
0
|
21
|
10
|
2
|
12
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Intracellular Imaging of HCV RNA and Cellular Lipids by Using Simultaneous Two-Photon Fluorescence and Coherent Anti-Stokes Raman Scattering Microscopies
|
0
|
0
|
0
|
0
|
72
|
68
|
1
|
69
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Intramers and Aptamers: Applications in Protein-Function Analyses and Potential for Drug Screening
|
0
|
0
|
0
|
0
|
53
|
42
|
6
|
48
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Intraribosomal Regulation of Expression and Fate of Proteins
|
0
|
0
|
0
|
0
|
17
|
13
|
0
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Inversion of Stereoselectivity by Applying Mutants of the Hydroxynitrile Lyase from Manihot esculenta
|
0
|
0
|
0
|
0
|
14
|
7
|
1
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Investigating Nonribosomal Peptide and Polyketide Biosynthesis by Direct Detection of Intermediates on >70 kDa Polypeptides by Using Fourier-Transform Mass Spectrometry
|
0
|
0
|
0
|
0
|
36
|
23
|
4
|
27
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Investigation of Molecular Beacon Aptamer-Based Bioassay for Platelet-Derived Growth Factor Detection
|
0
|
0
|
0
|
0
|
44
|
48
|
2
|
50
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Investigation of the Mechanism of Resistance to Third-Generation Cephalosporins by Class C β-Lactamases by Using Chemical Complementation
|
0
|
0
|
0
|
0
|
19
|
11
|
4
|
15
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Isolation and Amino Acid Sequence of a Serine Proteinase Inhibitor from Common Flax (Linum usitatissimum) Seeds
|
0
|
0
|
0
|
0
|
22
|
7
|
4
|
11
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Kanamycin A-Derived Cationic Lipids as Vectors for Gene Transfection
|
0
|
0
|
0
|
0
|
27
|
13
|
0
|
13
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Ketoreduction in Mycolactone Biosynthesis: Insight into Substrate Specificity and Stereocontrol from Studies of Discrete Ketoreductase Domains in vitro
|
0
|
0
|
0
|
0
|
60
|
50
|
6
|
56
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Key Players Involved in Bacterial Disulfide-Bond Formation
|
0
|
0
|
0
|
0
|
26
|
11
|
1
|
12
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Kinase Data Mining: Dealing with the Information (Over-)Flow
|
0
|
0
|
0
|
0
|
34
|
22
|
4
|
26
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Kinetic Monitoring of Self-Replicating Systems through Measurement of Fluorescence Resonance Energy Transfer
|
0
|
0
|
0
|
0
|
10
|
11
|
1
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Kinetics Study of Bungarus fasciatus Venom Acetylcholinesterase Immobilised on a Langmuir-Blodgett Proteo-Glycolipidic Bilayer
|
0
|
0
|
0
|
0
|
20
|
15
|
2
|
17
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Kurt Wüthrich, the ETH Zürich, and the Development of NMR Spectroscopy for the Investigation of Structure, Dynamics, and Folding of Proteins
|
0
|
0
|
0
|
0
|
24
|
5
|
1
|
6
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Laboratory Evolution of P450 BM-3 for Mediated Electron Transfer
|
0
|
0
|
0
|
0
|
51
|
32
|
14
|
46
|
4
|
0
|
0
|
1
|
0
|
0
|
|
LanGT2 Catalyzes the First Glycosylation Step during Landomycin A Biosynthesis
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0
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0
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0
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0
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13
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6
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2
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8
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4
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0
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LanV, a Bifunctional Enzyme: Aromatase and Ketoreductase during Landomycin A Biosynthesis
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0
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0
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0
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0
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10
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10
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0
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10
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3
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Lanthanide-Binding Tags as Versatile Protein Coexpression Probes
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75
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82
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Large-Scale In Vivo Synthesis of the Carbohydrate Moieties of Gangliosides GM1 and GM2 by Metabolically Engineered Escherichia coli
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35
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26
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5
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31
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3
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0
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Latent Blue and Red Fluorophores Based on the Trimethyl Lock
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0
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0
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42
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33
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5
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38
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1
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Learning from Directed Evolution: Further Lessons from Theoretical Investigations into Cooperative Mutations in Lipase Enantioselectivity
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168
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Learning from Directed Evolution: Theoretical Investigations into Cooperative Mutations in Lipase Enantioselectivity
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0
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22
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25
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1
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26
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3
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0
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0
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0
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Leucyl/Phenylalanyl-tRNA-Protein Transferase-Mediated Chemoenzymatic Coupling of N-Terminal Arg/Lys Units in Post-translationally Processed Proteins with Non-natural Amino Acids
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0
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29
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Life - As a Matter of Fat: The Emerging Science of Lipidomics.By Ole G. Mouritsen.
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18
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4
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4
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3
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0
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0
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Ligand Binding Transmits Conformational Changes across the Membrane-Spanning Region to the Intracellular Side of the 5-HT3 Serotonin Receptor
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0
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0
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0
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0
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15
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13
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3
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16
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0
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Ligand-Binding Modes in Cationic Biogenic Amine Receptors
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24
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14
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6
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20
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3
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Light-Activated Transcription and Repression by Using Photocaged SERMs
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0
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0
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21
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6
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2
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8
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Light-Induced Formation of G-Quadruplex DNA Secondary Structures
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29
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6
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32
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Lighting Up Biochemiluminescence by the Surface Self-Assembly of DNA-Hemin Complexes
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0
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0
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0
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23
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16
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3
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19
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Linking the Fields - The Interplay of Organic Synthesis, Biophysical Chemistry, and Cell Biology in the Chemical Biology of Protein Lipidation
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19
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22
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22
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5
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Lipase-Specific Foldases
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69
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32
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4
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36
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11
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0
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Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology. Edited by Christopher J. Fielding.
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0
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0
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15
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8
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1
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9
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6
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0
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0
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0
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Lipidic Membranes Are Potential “Catalysts” in the Ligand Activity of the Multifunctional Pentapeptide Neokyotorphin
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0
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0
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0
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0
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6
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4
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1
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5
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0
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0
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0
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0
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Lipoconjugates for the Noncovalent Generation of Microarrays in Biochemical and Cellular Assays
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0
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0
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0
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0
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19
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13
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1
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14
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1
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0
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0
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0
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0
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Loading of the Antigen-Presenting Protein CD1d with Synthetic Glycolipids
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0
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0
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0
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0
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24
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8
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1
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9
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1
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0
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0
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0
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Locating the Metal Ion in Calcium-Binding Proteins by Using Cerium(III) as a Probe
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0
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0
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0
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0
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2
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5
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3
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8
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3
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0
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0
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0
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0
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Locked Nucleic Acids and Intercalating Nucleic Acids in the Design of Easily Denaturing Nucleic Acids: Thermal Stability Studies
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0
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0
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0
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0
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30
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18
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1
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19
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0
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0
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Looking at Molecules - An Essay on Art and Science
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0
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22
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11
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1
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12
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2
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0
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0
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0
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Loop Flexibility and Solvent Dynamics as Determinants for the Selective Inhibition of Cyclin-Dependent Kinase 4: Comparative Molecular Dynamics Simulation Studies of CDK2 and CDK4
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0
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0
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33
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24
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1
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25
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8
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0
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0
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0
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Low Micromolar Inhibitors of Galectin-3 Based on 3′-Derivatization of N-Acetyllactosamine
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0
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0
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0
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0
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13
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29
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5
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34
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8
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0
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0
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0
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Luminescent Saccharide Biosensor by Using Lanthanide-Bound Lectin Labeled with Fluorescein
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0
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0
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0
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34
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27
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4
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31
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4
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Macrocyclic Hairpin Mimetics of the Cationic Antimicrobial Peptide Protegrin I: A New Family of Broad-Spectrum Antibiotics
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31
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5
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18
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5
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0
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Macrophomate Synthase: The First Structure of a Natural Diels-Alderase
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0
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0
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0
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0
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30
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14
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0
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14
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3
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0
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0
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Malassezin, a Novel Agonist of the Aryl Hydrocarbon Receptor from the Yeast Malassezia furfur, Induces Apoptosis in Primary Human Melanocytes
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0
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0
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0
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0
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28
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14
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0
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14
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3
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1
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0
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0
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0
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Manumycin A and Its Analogues Are Irreversible Inhibitors of Neutral Sphingomyelinase
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0
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0
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0
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0
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31
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8
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3
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11
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18
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0
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0
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0
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0
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Mapping Protease Substrates by Using a Biotinylated Phage Substrate Library
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0
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0
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0
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0
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70
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43
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7
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50
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9
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0
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0
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0
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0
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0
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Mechanism and Substrate Specificity of tRNA-Guanine Transglycosylases (TGTs): tRNA-Modifying Enzymes from the Three Different Kingdoms of Life Share a Common Catalytic Mechanism
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0
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0
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0
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0
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26
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18
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8
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26
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2
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0
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0
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0
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0
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0
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Mechanism of Action of Tubulysin, an Antimitotic Peptide from Myxobacteria
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0
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0
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0
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0
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70
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56
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7
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63
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10
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0
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0
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0
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0
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Mechanism-Based Fluorescent Reporter for Protein Kinase A Detection
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0
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0
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0
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0
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35
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22
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1
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23
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4
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0
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0
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0
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Mechanisms of Protein Folding: Molecular Chaperones and Their Application in Biotechnology
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0
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0
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44
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21
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1
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22
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13
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0
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0
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0
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Mechanistic Implications of Escherichia coli Galactokinase Structure-Based Engineering
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0
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0
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0
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0
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12
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8
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0
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8
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0
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0
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0
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Mechanistic Investigation into Complementary (Antisense) Peptide Mini-Receptor Inhibitors of Cytokine Interleukin-1
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0
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0
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0
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0
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15
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8
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3
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11
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2
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0
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0
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0
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0
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0
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Mechanistic Studies on the Tyrosinase-Catalyzed Formation of the Anachelin Chromophore
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0
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0
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0
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0
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51
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25
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0
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25
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4
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0
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Membrane Protein-Lipid Interactions in Mixed Micelles Studied by NMR Spectroscopy with the Use of Paramagnetic Reagents
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48
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32
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Metabolic Engineering of Aminocoumarins: Inactivation of the Methyltransferase Gene cloP and Generation of New Clorobiocin Derivatives in a Heterologous Host
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0
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0
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0
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0
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24
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16
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0
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16
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9
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0
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0
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0
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Metal Ion Effects on the cis/trans Isomerization Equilibrium of Proline in Short-Chain Peptides: A Solution NMR Study
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0
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0
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0
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0
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11
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11
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2
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13
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0
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0
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0
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0
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Metal-Chelating Amino Acids As Building Blocks For Synthetic Receptors Sensing Metal Ions And Histidine-Tagged Proteins
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0
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0
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0
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0
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20
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17
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17
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Methods in Molecular Biology 319: Cell Imaging Techniques: Methods and Protocols. Edited by Douglas J. Taatjes and Brooke T. Mossman.
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0
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0
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0
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11
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3
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0
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3
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Methods in Molecular Biology 352: Protein Engineering Protocols. Edited by Katja M. Arndt, and Kristian M. Müller.
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7
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33
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Methods in Molecular Biology Vol. 261: Protein-Protein Interactions: Methods and Applications. Edited by Haian Fu.
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0
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0
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16
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4
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1
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5
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Methods in Molecular Biology Vol. 265: RNA Interference, Editing, and Modification. Edited by Jonatha M. Gott.
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0
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0
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0
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9
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1
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0
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1
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3
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0
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0
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Methods in Molecular Biology, Vol. 257: mRNA Processing and Metabolism: Methods and Protocols. Edited by Daniel R. Schoenberg.
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0
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0
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6
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1
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0
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1
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3
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0
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0
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Methods in Molecular Biology, Vol. 262: Genetic Recombination Reviews and Protocols. Edited by Alan S. Waldman.
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0
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0
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0
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22
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1
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0
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1
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3
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0
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0
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0
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Methods in Molecular Biology, Vol. 300: Protein Nanotechnology: Protocols, Instrumentation, and Applications. Edited by Tuan Vo-Dinh.
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0
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0
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0
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0
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8
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2
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0
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2
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0
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0
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0
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0
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Methods in Molecular Biology, Vol. 310: Chemical Genomics: Reviews and Protocols. Edited by Edward Zanders.
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0
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0
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0
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0
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13
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3
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0
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3
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1
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0
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0
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0
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0
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Methods in Molecular Biology, Vol. 335: Fluorescent Energy Transfer Nucleic Acid Probes: Designs and Protocols. Edited by Vladimir V. Didenko.
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0
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0
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32
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23
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1
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24
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2
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0
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Methods in Molecular Biology, Vol. 340: Protein Design: Methods and Applications. Edited by Raphael Guerois and Manuela López de la Paz.
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0
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0
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0
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17
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23
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30
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Methods in Pharmacology and Toxicology: Optimization in Drug Discovery: In Vitro Methods. By Zhengyin Yan and Gary W. Caldwell.
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0
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0
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0
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0
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3
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0
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1
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1
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0
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0
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0
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0
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0
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0
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Methyl Groups as Probes of Structure and Dynamics in NMR Studies of High-Molecular-Weight Proteins
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0
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0
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67
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55
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10
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65
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6
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0
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0
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Microbial Desaturation of Bis(1-chloro-2-propyl) Ether into a Dichloro Vinyl Ether
|
0
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0
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0
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0
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7
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1
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0
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1
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1
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0
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0
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0
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0
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0
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|
Microsecond Protein Dynamics Measured by 13Cα Rotating-Frame Spin Relaxation
|
0
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0
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0
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0
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15
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10
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4
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14
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0
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0
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0
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0
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0
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0
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Microtiter Plate-Based Screening for the Optimization of DNA-Protein Conjugate Synthesis by Means of Expressed Protein Ligation
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0
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0
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0
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0
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66
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112
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10
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122
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5
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0
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0
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0
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Miniature Protein Inhibitors of the p53-hDM2 Interaction
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0
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0
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0
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0
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51
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35
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7
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42
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5
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0
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0
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0
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0
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0
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Miniaturization of Microwave-Assisted Carbohydrate Functionalization to Create Oligosaccharide Microarrays
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0
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0
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0
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0
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56
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45
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2
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47
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5
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0
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0
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0
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0
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Mirror-image Phage Display: Aiming at the Mirror
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0
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0
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0
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52
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18
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2
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20
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16
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0
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0
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0
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Mixed-Linkage Cellooligosaccharides: A New Class of Glycoside Hydrolase Inhibitors
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0
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0
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0
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30
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12
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4
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16
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0
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0
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0
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0
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0
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0
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Model Studies on a Carprofen Derivative as Dual Photosensitizer for Thymine Dimerization and (6-4) Photoproduct Repair
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0
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0
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0
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0
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91
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105
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115
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0
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0
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0
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Modelling of Photointermediates Suggests a Mechanism of the Flip of the β-Ionone Moiety of the Retinylidene Chromophore in the Rhodopsin Photocascade
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0
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0
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0
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0
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13
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19
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0
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19
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0
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0
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Modern Fluoroorganic Chemistry. Synthesis, Reactivity, Applications. By Peer Kirsch.
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0
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0
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0
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0
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4
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4
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0
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4
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2
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0
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0
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0
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0
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0
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Modification of Galactose Oxidase to Introduce Glucose 6-Oxidase Activity
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0
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0
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0
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18
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15
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1
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16
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Modified DNA Bearing 5(Methoxycarbonylmethyl)-2′-deoxyuridine: Preparation by PCR with Thermophilic DNA Polymerase and Postsynthetic Derivatization
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0
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0
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0
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0
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16
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11
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0
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11
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0
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0
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0
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Modified Microperoxidases Exhibit Different Reactivity Towards Phenolic Substrates
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0
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0
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0
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17
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5
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0
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5
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5
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0
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0
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0
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0
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0
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Modified Oligonucleotides Containing Lithocholic Acid in Their Backbones: Their Enhanced Cellular Uptake and Their Mimicking of Hairpin Structures
|
0
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0
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0
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0
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9
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10
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1
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11
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3
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0
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0
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Modular Protein Domains. Edited by Giovanni Cesareni, Mario Gimona, Marius Sudol, and Michael Yaffe.
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0
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0
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0
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0
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6
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0
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2
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2
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3
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0
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0
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Modulated Nucleoside Kinases as Tools to Improve the Activation of Therapeutic Nucleoside Analogues
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0
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0
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0
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0
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8
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6
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0
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6
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1
|
0
|
0
|
0
|
0
|
0
|
|
Modulating Functional Loop Movements: The Role of Highly Conserved Residues in the Correlated Loop Motions
|
0
|
0
|
0
|
0
|
14
|
8
|
2
|
10
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Modulation of Infectivity in Phage Display as a Tool to Determine the Substrate Specificity of Proteases
|
0
|
0
|
0
|
0
|
35
|
20
|
0
|
20
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Moenomycin-Mediated Affinity Purification of Penicillin-Binding Protein 1b
|
0
|
0
|
0
|
0
|
18
|
13
|
1
|
14
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Basis for the Enhanced Lipase-Catalyzed N-Acylation of 1-Phenylethanamine with Methoxyacetate
|
0
|
0
|
0
|
0
|
41
|
43
|
3
|
46
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Basis of Phospholipase A2 Inhibition by Petrosaspongiolide M
|
0
|
0
|
0
|
0
|
14
|
11
|
0
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Basis of Phospholipase A2 Inhibition by Petrosaspongiolide M
|
0
|
0
|
0
|
0
|
0
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Basis of Substrate Recognition in D-3-Hydroxybutyrate Dehydrogenase from Pseudomonas putida
|
0
|
0
|
0
|
0
|
31
|
19
|
5
|
24
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Basis of the Interaction Specificity between the Human Glucocorticoid Receptor and Its Endogenous Steroid Ligand Cortisol
|
0
|
0
|
0
|
0
|
41
|
35
|
2
|
37
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass
|
0
|
0
|
0
|
0
|
12
|
12
|
2
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Machines for Protein Degradation
|
0
|
0
|
0
|
0
|
193
|
121
|
25
|
146
|
33
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Mechanisms of Death-Receptor-Mediated Apoptosis
|
0
|
0
|
0
|
0
|
62
|
31
|
7
|
38
|
20
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Neuropharmacology: Strategies and Methods. Edited by Arne Schousboe and Hans Bräuner-Osborne.
|
0
|
0
|
0
|
0
|
11
|
3
|
1
|
4
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Recognition of Complementary Liposomes in Modeling Cell-Cell Recognition
|
0
|
0
|
0
|
0
|
21
|
17
|
4
|
21
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Molecular Transporters: Synthesis of Oligoguanidinium Transporters and Their Application to Drug Delivery and Real-Time Imaging
|
0
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0
|
0
|
0
|
116
|
107
|
16
|
123
|
37
|
0
|
0
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1
|
0
|
0
|
|
Molecules as Modulators: Systems Biology Challenges Chemistry
|
0
|
0
|
0
|
0
|
10
|
8
|
0
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Mollusk Shell Acidic Proteins: In Search of Individual Functions
|
0
|
0
|
0
|
0
|
64
|
49
|
17
|
66
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Monitoring Chemical Reactions by Using Ion-Channel-Forming Peptides
|
0
|
0
|
0
|
0
|
17
|
13
|
6
|
19
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Monitoring in Real Time with a Microelectrode the Release of Reactive Oxygen and Nitrogen Species by a Single Macrophage Stimulated by its Membrane Mechanical Depolarization
|
0
|
0
|
0
|
0
|
53
|
38
|
2
|
40
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Monitoring the Cellular Surface Display of Recombinant Proteins by Cysteine Labeling and Flow Cytometry
|
0
|
0
|
0
|
0
|
30
|
17
|
3
|
20
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Multidisciplinary Experimental Approaches to Characterizing Biomolecular Dynamics
|
0
|
0
|
0
|
0
|
11
|
7
|
1
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Multifunctional Folded Polypeptides from Peptide Synthesis and Site-Selective Self-Functionalization - Practical Scaffolds in Aqueous Solution
|
0
|
0
|
0
|
0
|
13
|
7
|
1
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Multiparameter Imaging for the Analysis of Intracellular Signaling
|
0
|
0
|
0
|
0
|
60
|
37
|
15
|
52
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Multiple Site-Specific Binding of Fis Protein to Escherichia coli nuoA-N Promoter DNA and its Impact on DNA Topology Visualised by Means of Scanning Force Microscopy
|
0
|
0
|
0
|
0
|
13
|
7
|
2
|
9
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Multiplex-PCR-Based Recombination as a Novel High-Fidelity Method for Directed Evolution
|
0
|
0
|
0
|
0
|
58
|
36
|
6
|
42
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Multitasking by Multivalent Circular DNA Aptamers
|
0
|
0
|
0
|
0
|
59
|
33
|
4
|
37
|
17
|
0
|
0
|
0
|
0
|
0
|
|
Multivalent HSA Conjugates of 3′-Sialyllactose are Potent Inhibitors of Adenoviral Cell Attachment and Infection
|
0
|
0
|
0
|
0
|
22
|
30
|
1
|
31
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Mutagenic Stabilization of the Photocycle Intermediate of Green Fluorescent Protein (GFP)
|
0
|
0
|
0
|
0
|
13
|
8
|
1
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Mutants of 4-Oxalocrotonate Tautomerase Catalyze the Decarboxylation of Oxaloacetate through an Imine Mechanism
|
0
|
0
|
0
|
0
|
6
|
4
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Mutational Analysis of a Key Residue in the Substrate Specificity of a Cephalosporin Acylase
|
0
|
0
|
0
|
0
|
24
|
11
|
1
|
12
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Mutational Analysis of the Kinetics and Thermodynamics of Transcription Factor NF-κB Homodimerisation
|
0
|
0
|
0
|
0
|
16
|
11
|
0
|
11
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Mutational Studies Confirm the Catalytic Triad in the Human Selenoenzyme Thioredoxin Reductase Predicted by Molecular Modeling
|
0
|
0
|
0
|
0
|
48
|
30
|
5
|
35
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Myxovirescin A Biosynthesis is Directed by Hybrid Polyketide Synthases/Nonribosomal Peptide Synthetase, 3-Hydroxy-3-Methylglutaryl-CoA Synthases, and trans-Acting Acyltransferases
|
0
|
0
|
0
|
0
|
111
|
65
|
16
|
81
|
19
|
0
|
0
|
0
|
0
|
0
|
|
NF-κB: A Multifaceted Transcription Factor Regulated at Several Levels
|
0
|
0
|
0
|
0
|
177
|
96
|
28
|
124
|
52
|
0
|
0
|
0
|
0
|
0
|
|
NMR Backbone Assignment of a Protein Kinase Catalytic Domain by a Combination of Several Approaches: Application to the Catalytic Subunit of cAMP-Dependent Protein Kinase
|
0
|
0
|
0
|
0
|
26
|
23
|
3
|
26
|
3
|
0
|
0
|
0
|
0
|
0
|
|
NMR Chemical Shift Perturbation Study of the N-Terminal Domain of Hsp90 upon Binding of ADP, AMP-PNP, Geldanamycin, and Radicicol
|
0
|
0
|
0
|
0
|
50
|
26
|
3
|
29
|
6
|
0
|
0
|
0
|
0
|
0
|
|
NMR Methods for Studying the Structure and Dynamics of RNA
|
0
|
0
|
0
|
0
|
91
|
79
|
13
|
92
|
6
|
0
|
0
|
0
|
0
|
0
|
|
NMR Solution Structure, Backbone Mobility, and Homology Modeling of c-Type Cytochromes from Gram-Positive Bacteria
|
0
|
0
|
0
|
0
|
18
|
12
|
4
|
16
|
3
|
0
|
0
|
0
|
0
|
0
|
|
NMR Spectroscopy of Paramagnetic Metalloproteins
|
0
|
0
|
0
|
0
|
57
|
51
|
7
|
58
|
13
|
0
|
0
|
0
|
0
|
0
|
|
NMR Spectroscopy of RNA
|
0
|
0
|
0
|
0
|
87
|
94
|
4
|
98
|
9
|
0
|
0
|
0
|
0
|
0
|
|
NMR Structural Model of the Interaction of Herbicides with the Photosynthetic Reaction Center from Rhodobacter sphaeroides
|
0
|
0
|
0
|
0
|
3
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
NMR Structure of the (+)-CPI-indole/d(GACTAATTGAC)-d(GTCAATTAGTC) Covalent Complex
|
0
|
0
|
0
|
0
|
20
|
8
|
1
|
9
|
0
|
0
|
0
|
0
|
0
|
0
|
|
NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein
|
0
|
0
|
0
|
0
|
25
|
8
|
5
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
NMR and Modeling Studies of Protein-Carbohydrate Interactions: Synthesis, Three-Dimensional Structure, and Recognition Properties of a Minimum Hevein Domain with Binding Affinity for Chitooligosaccharides
|
0
|
0
|
0
|
0
|
27
|
26
|
4
|
30
|
3
|
0
|
0
|
0
|
0
|
0
|
|
NMR in Pharmacokinetic and Pharmacodynamic Profiling
|
0
|
0
|
0
|
0
|
30
|
25
|
3
|
28
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Nanobiotechnology: Concepts, Applications and Perspectives. Edited by C. M. Niemeyer and C. A. Mirkin.
|
0
|
0
|
0
|
0
|
31
|
6
|
0
|
6
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Nanosecond Time-Resolved Fluorescence Protease Assays
|
0
|
0
|
0
|
0
|
42
|
24
|
0
|
24
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Nanostructured Ordering of Fluorescent Markers and Single Proteins on Substrates
|
0
|
0
|
0
|
0
|
40
|
29
|
1
|
30
|
5
|
2
|
0
|
0
|
0
|
0
|
|
Natural Deuterium Distribution in Branched-Chain Medium-Length Fatty Acids is Nonstatistical: A Site-Specific Study by Quantitative 2H NMR Spectroscopy of the Fatty Acids of Capsaicinoids
|
0
|
0
|
0
|
0
|
16
|
6
|
3
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Natural Deuterium Distribution in Fatty Acids Isolated from Peanut Seed Oil: A Site-Specific Study by Quantitative 2H NMR Spectroscopy
|
0
|
0
|
0
|
0
|
6
|
1
|
0
|
1
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Natural Deuterium Distribution in Long-Chain Fatty Acids Is Nonstatistical: A Site-Specific Study by Quantitative 2H NMR Spectroscopy
|
0
|
0
|
0
|
0
|
8
|
9
|
3
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Natural Products from Marine Microorganisms
|
0
|
0
|
0
|
0
|
91
|
18
|
1
|
19
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Natural Products from Marine Organisms and Their Associated Microbes
|
0
|
0
|
0
|
0
|
308
|
139
|
14
|
153
|
73
|
0
|
0
|
0
|
0
|
0
|
|
Natural and Non-natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
|
0
|
0
|
0
|
0
|
92
|
42
|
6
|
48
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Nature Encyclopedia of the Human Genome. Edited by David Cooper.
|
0
|
0
|
0
|
0
|
10
|
0
|
0
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Nature's Gift to Science (Nobel Lecture)
|
0
|
0
|
0
|
0
|
18
|
19
|
5
|
24
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Neem - An Omnipotent Plant: A Retrospection
|
0
|
0
|
0
|
0
|
469
|
39
|
6
|
45
|
52
|
0
|
0
|
0
|
0
|
0
|
|
New Allosteric Modulators of Metabotropic Glutamate Receptor 5 (mGluR5) Found by Ligand-Based Virtual Screening
|
0
|
0
|
0
|
0
|
43
|
25
|
3
|
28
|
4
|
0
|
0
|
0
|
0
|
0
|
|
New Dendrimer-Peptide Host-Guest Complexes: Towards Dendrimers as Peptide Carriers
|
0
|
0
|
0
|
0
|
77
|
54
|
2
|
56
|
8
|
0
|
0
|
0
|
0
|
0
|
|
New Inhibitors of the Tat-TAR RNA Interaction Found with a “Fuzzy” Pharmacophore Model
|
0
|
0
|
0
|
0
|
33
|
17
|
3
|
20
|
10
|
0
|
0
|
0
|
0
|
0
|
|
New Insights for Pursuing High Relaxivity MRI Agents from Modelling the Binding Interaction of GdIII Chelates to HSA
|
0
|
0
|
0
|
0
|
16
|
12
|
3
|
15
|
3
|
0
|
0
|
0
|
0
|
0
|
|
New Insights into the Mechanistic Details of the Carbonic Anhydrase Cycle as Derived from the Model System [(NH3)3Zn(OH)]+/CO2
|
0
|
0
|
0
|
0
|
16
|
12
|
1
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
New Light on a Long-Known Protein Family
|
0
|
0
|
0
|
0
|
27
|
7
|
1
|
8
|
3
|
0
|
0
|
0
|
0
|
0
|
|
New Light-Sensitive Nucleosides for Caged DNA Strand Breaks
|
0
|
0
|
0
|
0
|
20
|
20
|
4
|
24
|
0
|
0
|
0
|
0
|
0
|
0
|
|
New Methods for the Generation of Carbohydrate Arrays on Glass Slides and Their Evaluation
|
0
|
0
|
0
|
0
|
27
|
27
|
5
|
32
|
4
|
0
|
0
|
0
|
0
|
0
|
|
New Photoremovable Protecting Groups for Carboxylic Acids with High Photolytic Efficiencies at Near-UV Irradiation. Application to the Photocontrolled Release of L-Glutamate
|
0
|
0
|
0
|
0
|
135
|
82
|
7
|
89
|
14
|
0
|
1
|
0
|
0
|
0
|
|
New Rapamycin Derivatives by Precursor-Directed Biosynthesis
|
0
|
0
|
0
|
0
|
29
|
13
|
1
|
14
|
4
|
0
|
0
|
0
|
0
|
0
|
|
New Studies on the Murchison Meteorite Shed Light on the Pre-RNA World
|
0
|
0
|
0
|
0
|
37
|
10
|
1
|
11
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Nitric Oxide Reductase: Direct Electrochemistry and Electrocatalytic Activity
|
0
|
0
|
0
|
0
|
39
|
40
|
2
|
42
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Nitric Oxide-Induced Fluorescence Enhancement by Displacement of Dansylated Ligands from Cobalt
|
0
|
0
|
0
|
0
|
34
|
36
|
0
|
36
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Nitrosation of N-Terminally Blocked Tryptophan and Tryptophan-Containing Peptides by Peroxynitrite
|
0
|
0
|
0
|
0
|
46
|
69
|
6
|
75
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Noncovalent Binding of a Reaction Intermediate by a Designed Helix-Loop-Helix Motif - Implications for Catalyst Design
|
0
|
0
|
0
|
0
|
11
|
5
|
0
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Nonenzymatic Ligation of Short-Chained 2′-5′- or 3′-5′-Linked Oligoribonucleotides on 2′-5′- or 3′-5′-Linked Complementary Templates
|
0
|
0
|
0
|
0
|
9
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Nonribosomal Peptide Synthesis in Schizosaccharomyces pombe and the Architectures of Ferrichrome-Type Siderophore Synthetases in Fungi
|
0
|
0
|
0
|
0
|
82
|
54
|
11
|
65
|
23
|
0
|
0
|
0
|
0
|
0
|
|
Novel Activators of the Tumour Suppressor p53
|
0
|
0
|
0
|
0
|
12
|
4
|
2
|
6
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Novel Acyclic Deoxystreptamine Mimetics Targeting the Ribosomal Decoding Site
|
0
|
0
|
0
|
0
|
41
|
26
|
2
|
28
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Novel Aza Peptide Inhibitors and Active-Site Probes of Papain-Family Cysteine Proteases
|
0
|
0
|
0
|
0
|
69
|
45
|
2
|
47
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Novel Bcl-2 Inhibitors: Discovery and Mechanism Study of Small Organic Apoptosis-Inducing Agents
|
0
|
0
|
0
|
0
|
128
|
165
|
17
|
182
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Novel Carboranes with a DNA Binding Unit for the Treatment of Cancer by Boron Neutron Capture Therapy
|
0
|
0
|
0
|
0
|
24
|
20
|
2
|
22
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Novel Dications with Unfused Aromatic Systems: Trithiophene and Trifuran Derivatives of Furimidazoline
|
0
|
0
|
0
|
0
|
21
|
15
|
2
|
17
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Novel Factor XIII Probes for Blood Coagulation Imaging
|
0
|
0
|
0
|
0
|
24
|
13
|
3
|
16
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Novel Five-Membered Iminocyclitol Derivatives as Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis
|
0
|
0
|
0
|
0
|
75
|
61
|
4
|
65
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Novel Fluorescent Phosphonic Acid Esters for Discrimination of Lipases and Esterases
|
0
|
0
|
0
|
0
|
36
|
29
|
7
|
36
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Novel Hyperbranched Glycomimetics Recognized by the Human Mannose Receptor: Quinic or Shikimic Acid Derivatives as Mannose Bioisosteres
|
0
|
0
|
0
|
0
|
17
|
15
|
5
|
20
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Novel Insights into Siderophore Formation in Myxobacteria
|
0
|
0
|
0
|
0
|
25
|
19
|
2
|
21
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Novel Paromamine Derivatives Exploring Shallow-Groove Recognition of Ribosomal- Decoding-Site RNA
|
0
|
0
|
0
|
0
|
30
|
19
|
1
|
20
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Novel Trifluoromethyl Ketones as Potent Gastric Lipase Inhibitors
|
0
|
0
|
0
|
0
|
42
|
31
|
3
|
34
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Nuclear Localisation Sequence Templated Nonviral Gene Delivery Vectors: Investigation of Intracellular Trafficking Events of LMD and LD Vector Systems
|
0
|
0
|
0
|
0
|
73
|
33
|
6
|
39
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Nucleic Acid Aptamers as Tools and Drugs: Recent Developments
|
0
|
0
|
0
|
0
|
141
|
70
|
5
|
75
|
25
|
0
|
0
|
0
|
0
|
0
|
|
Nucleic Acid Supercoiling as a Means for Ionic Switching of DNA-Nanoparticle Networks
|
0
|
0
|
0
|
0
|
32
|
25
|
5
|
30
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Nucleobase Amino Acids Incorporated into the HIV-1 Nucleocapsid Protein Increased the Binding Affinity and Specificity for a Hairpin RNA
|
0
|
0
|
0
|
0
|
15
|
11
|
1
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Nucleophile Selectivity of Chorismate-Utilizing Enzymes
|
0
|
0
|
0
|
0
|
38
|
41
|
1
|
42
|
11
|
2
|
0
|
0
|
0
|
0
|
|
Nucleoside Analogues as Inhibitors of Thymidylate Kinases: Possible Therapeutic Applications
|
0
|
0
|
0
|
0
|
10
|
7
|
1
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology and Biological Applications. Edited by Morteza Vaghefi.
|
0
|
0
|
0
|
0
|
12
|
4
|
0
|
4
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Nucleoside-Based Phospholipids and Their Liposomes Formed in Water
|
0
|
0
|
0
|
0
|
5
|
5
|
1
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Oligo(ethylene glycol) Derivatives of Thioflavin T as Inhibitors of Protein-Amyloid Interactions
|
0
|
0
|
0
|
0
|
28
|
26
|
7
|
33
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Oligonucleotide Bearing Ethylenediamine-N,N,N′-Triacetates for Gap-Selective DNA Hydrolysis by Ce4+/EDTA
|
0
|
0
|
0
|
0
|
8
|
4
|
1
|
5
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Oligonucleotide-Based Knockdown Technologies: Antisense Versus RNA Interference
|
0
|
0
|
0
|
0
|
113
|
58
|
8
|
66
|
24
|
0
|
0
|
1
|
0
|
0
|
|
Oligoribonucleotide Analogues Containing a Mixed Backbone of Phosphodiester and Formacetal Internucleoside Linkages, Together with Vicinal 2′-O-Methyl Groups
|
0
|
0
|
0
|
0
|
75
|
85
|
3
|
88
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Oligosaccharide Mimics Containing Galactose and Fucose Specifically Label Tumour Cell Surfaces and Inhibit Cell Adhesion to Fibronectin
|
0
|
0
|
0
|
0
|
45
|
21
|
3
|
24
|
1
|
0
|
0
|
0
|
0
|
0
|
|
OmpA Membrane Domain as a Tight-Binding Anchor for Lipid Bilayers
|
0
|
0
|
0
|
0
|
16
|
5
|
6
|
11
|
3
|
0
|
0
|
0
|
0
|
0
|
|
On Secondary Structure Rearrangements and Equilibria of Small RNAs
|
0
|
0
|
0
|
0
|
0
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
On Secondary Structure Rearrangements and Equilibria of Small RNAs
|
0
|
0
|
0
|
0
|
24
|
17
|
1
|
18
|
5
|
0
|
0
|
0
|
0
|
0
|
|
On the Antimicrobial and Hemolytic Activities of Amphiphilic β-Peptides
|
0
|
0
|
0
|
0
|
12
|
10
|
1
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
On the Biodegradation of β-Peptides
|
0
|
0
|
0
|
0
|
15
|
12
|
1
|
13
|
3
|
0
|
0
|
0
|
0
|
0
|
|
On the Generation of Catalytic Antibodies by Transition State Analogues
|
0
|
0
|
0
|
0
|
24
|
11
|
0
|
11
|
3
|
0
|
0
|
0
|
0
|
0
|
|
On the Origin of Deoxypentoses: Evidence to Support a Glucose Progenitor in the Biosynthesis of Calicheamicin
|
0
|
0
|
0
|
0
|
17
|
12
|
0
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
On the Sequence of Bond Formation in Loline Alkaloid Biosynthesis
|
0
|
0
|
0
|
0
|
48
|
31
|
6
|
37
|
7
|
0
|
0
|
0
|
0
|
0
|
|
On the Transformation of (S)-2-Hydroxypropylphosphonic Acid into Fosfomycin in Streptomyces fradiae - A Unique Method of Epoxide Ring Formation
|
0
|
0
|
0
|
0
|
7
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
On the in vitro and in vivo Properties of Four Locked Nucleic Acid Nucleotides Incorporated into an Anti-H-Ras Antisense Oligonucleotide
|
0
|
0
|
0
|
0
|
52
|
32
|
5
|
37
|
4
|
0
|
0
|
0
|
0
|
0
|
|
On-Bead Chemical Synthesis and Display of Phosphopeptides for Affinity Pull-Down Proteomics
|
0
|
0
|
0
|
0
|
62
|
38
|
3
|
41
|
6
|
0
|
0
|
0
|
0
|
0
|
|
One-Bead-One-Inhibitor-One-Substrate Screening of Neuraminidase Activity
|
0
|
0
|
0
|
0
|
31
|
20
|
2
|
22
|
5
|
0
|
0
|
0
|
0
|
0
|
|
One-Pot TiO2-Catalyzed Synthesis of Nucleic Bases and Acyclonucleosides from Formamide: Implications for the Origin of Life
|
0
|
0
|
0
|
0
|
27
|
11
|
4
|
15
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Online Synthesis of Diblock Cationic Oligonucleotides for Enhanced Hybridization to their Complementary Sequence
|
0
|
0
|
0
|
0
|
22
|
10
|
3
|
13
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Onwards and Upwards
|
0
|
0
|
0
|
0
|
8
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Optimal Modification of Annexin V with Fluorescent Dyes
|
0
|
0
|
0
|
0
|
41
|
16
|
1
|
17
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Optimization and Modifications of Aptamers Selected from Live Cancer Cell Lines
|
0
|
0
|
0
|
0
|
60
|
60
|
3
|
63
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Optimization of Electrochemical and Peroxide-Driven Oxidation of Styrene with Ultrathin Polyion Films Containing Cytochrome P450cam and Myoglobin
|
0
|
0
|
0
|
0
|
20
|
14
|
4
|
18
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Optimization of Triple-Helix-Directed DNA Cleavage by Benzoquinoquinoxaline-Ethylenediaminetetraacetic Acid Conjugates
|
0
|
0
|
0
|
0
|
12
|
2
|
0
|
2
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Optimization of Xenon Biosensors for Detection of Protein Interactions
|
0
|
0
|
0
|
0
|
46
|
37
|
3
|
40
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Optimized Fluorescent Trimethoprim Derivatives for in vivo Protein Labeling
|
0
|
0
|
0
|
0
|
25
|
35
|
0
|
35
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Order for Free: Molecular Diversity and Complexity Promote Self-Organisation
|
0
|
0
|
0
|
0
|
3
|
4
|
1
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Organic Chemistry at the Interface to Biology
|
0
|
0
|
0
|
0
|
30
|
9
|
4
|
13
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Organic Fluorine: Odd Man Out
|
0
|
0
|
0
|
0
|
55
|
69
|
12
|
81
|
8
|
0
|
2
|
0
|
0
|
0
|
|
Organometallic Compounds with Biological Activity: A Very Selective and Highly Potent Cellular Inhibitor for Glycogen Synthase Kinase 3
|
0
|
0
|
0
|
0
|
86
|
59
|
12
|
71
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Origin of Informational Polymers: The Concurrent Roles of Formamide and Phosphates
|
0
|
0
|
0
|
0
|
34
|
24
|
2
|
26
|
3
|
0
|
1
|
0
|
0
|
0
|
|
Origins of RNA Catalysis in the Hairpin Ribozyme
|
0
|
0
|
0
|
0
|
11
|
3
|
4
|
7
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Oxidosqualene Cyclase Second-Sphere Residues Profoundly Influence the Product Profile
|
0
|
0
|
0
|
0
|
6
|
3
|
1
|
4
|
2
|
0
|
0
|
0
|
0
|
0
|
|
PARP-1: A Regulator of Genomic Stability Linked with Mammalian Longevity
|
0
|
0
|
0
|
0
|
17
|
8
|
1
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
PCR Troubleshooting: The Essential Guide. Edited by Michael L. Altshuler.
|
0
|
0
|
0
|
0
|
43
|
11
|
0
|
11
|
7
|
0
|
0
|
0
|
0
|
0
|
|
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a New Mitochondrial Benzodiazepine-Receptor Ligand, Induces Apoptosis in C6 glioma Cells
|
0
|
0
|
0
|
0
|
8
|
0
|
0
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
|
PTK 787/ZK 222584, a Tyrosine Kinase Inhibitor of all Known VEGF Receptors, Represses Tumor Growth with High Efficacy
|
0
|
0
|
0
|
0
|
88
|
44
|
8
|
52
|
24
|
0
|
0
|
0
|
0
|
0
|
|
Partial 13C and 15N Chemical-Shift Assignments of the Disulfide-Bond-Forming Enzyme DsbB by 3D Magic-Angle Spinning NMR Spectroscopy
|
0
|
0
|
0
|
0
|
108
|
104
|
8
|
112
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Partial Protection against Botulinum B Neurotoxin-Induced Blocking of Exocytosis by a Potent Inhibitor of Its Metallopeptidase Activity
|
0
|
0
|
0
|
0
|
26
|
15
|
6
|
21
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Partially Folded Conformations in the Folding Pathway of Bovine Carbonic Anhydrase II: A Fluorescence Spectroscopic Analysis
|
0
|
0
|
0
|
0
|
31
|
16
|
2
|
18
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Partially Reversible Adsorption of Annexin A1 on POPC/POPS Bilayers Investigated by QCM Measurements, SFM, and DMC Simulations
|
0
|
0
|
0
|
0
|
19
|
15
|
3
|
18
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Patterns of DNA-Labeled and scFv-Antibody-Carrying Lipid Vesicles Directed by Material-Specific Immobilization of DNA and Supported Lipid Bilayer Formation on an Au/SiO2 Template
|
0
|
0
|
0
|
0
|
35
|
29
|
2
|
31
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Peptide Arrays for Kinase Profiling
|
0
|
0
|
0
|
0
|
69
|
40
|
10
|
50
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Peptide Binding by One-Armed Receptors in Water: Screening of a Combinatorial Library for the Binding of Val-Val-Ile-Ala
|
0
|
0
|
0
|
0
|
13
|
16
|
0
|
16
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Peptide-Capped Gold Nanoparticles: Towards Artificial Proteins
|
0
|
0
|
0
|
0
|
199
|
134
|
13
|
147
|
16
|
0
|
0
|
0
|
0
|
0
|
|
Peptoid-Peptide Hybrids That Bind Syk SH2 Domains Involved in Signal Transduction
|
0
|
0
|
0
|
0
|
25
|
25
|
5
|
30
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Phage Display in Biotechnology and Drug Discovery. Edited by Sachdev Sidhu.
|
0
|
0
|
0
|
0
|
30
|
5
|
0
|
5
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Pheromone Synthesis, Part 203 Pheromonal and Kairomonal Activities Can Be Separated: Synthesis and Bioactivity Studies of Pine Bast Scale Sex Pheromones and Their Analogues
|
0
|
0
|
0
|
0
|
13
|
9
|
0
|
9
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Phosphate-Group Recognition by the Aptamer Domain of the Thiamine Pyrophosphate Sensing Riboswitch
|
0
|
0
|
0
|
0
|
74
|
59
|
2
|
61
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Phospholipases and Galactolipases Trigger Oxylipin-Mediated Wound-Activated Defence in the Red Alga Gracilaria chilensis against Epiphytes
|
0
|
0
|
0
|
0
|
22
|
16
|
0
|
16
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Phosphorylation-Induced Conformational Changes in Short Peptides Probed by Fluorescence Resonance Energy Transfer in the 10 Å Domain
|
0
|
0
|
0
|
0
|
61
|
109
|
4
|
113
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Photoactivation of an Inhibitor of the 12/15-Lipoxygenase Pathway
|
0
|
0
|
0
|
0
|
45
|
35
|
5
|
40
|
4
|
0
|
1
|
0
|
0
|
0
|
|
Photocaged Agonist for an Analogue-Specific form of the Vitamin D Receptor
|
0
|
0
|
0
|
0
|
4
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Photocontrol of DNA Duplex Formation by Using Azobenzene-Bearing Oligonucleotides
|
0
|
0
|
0
|
0
|
13
|
6
|
4
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Photocrosslinking in Ruthenium-Labelled Duplex Oligonucleotides
|
0
|
0
|
0
|
0
|
16
|
9
|
0
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Photogenerated Carbohydrate Microarrays
|
0
|
0
|
0
|
0
|
135
|
254
|
28
|
282
|
20
|
0
|
0
|
0
|
0
|
0
|
|
Photolabile Protection for One-Pot Sequential Native Chemical Ligation
|
0
|
0
|
0
|
0
|
41
|
24
|
5
|
29
|
1
|
0
|
1
|
1
|
0
|
0
|
|
Photoregulation of the Transcription Reaction of T7 RNA Polymerase by Tethering an Azobenzene to the Promoter
|
0
|
0
|
0
|
0
|
8
|
10
|
0
|
10
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Photoresponsive Dendritic Azobenzene Peptides
|
0
|
0
|
0
|
0
|
27
|
17
|
1
|
18
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Photoreversible Inhibition of Cholinesterases: Catalytic Serine-Labeled Caged Butyrylcholinesterase
|
0
|
0
|
0
|
0
|
12
|
7
|
1
|
8
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Picosecond Time-Resolved Fluorescence from Blue-Emitting Chromophore Variants Y66F and Y66H of the Green Fluorescent Protein
|
0
|
0
|
0
|
0
|
29
|
20
|
6
|
26
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Piperidine Glycosides Targeting the Ribosomal Decoding Site
|
0
|
0
|
0
|
0
|
12
|
11
|
0
|
11
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Pityriarubins, Novel Highly Selective Inhibitors of Respiratory Burst from Cultures of the Yeast Malassezia furfur: Comparison with the Bisindolylmaleimide Arcyriarubin A
|
0
|
0
|
0
|
0
|
25
|
13
|
0
|
13
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Plant “Polyphenolic” Small Molecules Can Induce a Calorie Restriction-Mimetic Life-Span Extension by Activating Sirtuins: Will “Polyphenols” Someday Be Used as Chemotherapeutic Drugs in Western Medicine?
|
0
|
0
|
0
|
0
|
48
|
18
|
3
|
21
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Platinum(II)-Based Coordination Compounds as Nucleic Acid Labeling Reagents: Synthesis, Reactivity, and Applications in Hybridization Assays
|
0
|
0
|
0
|
0
|
29
|
13
|
4
|
17
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Polyaza Crown Ethers as Non-Nucleosidic Building Blocks in DNA Conjugates: Synthesis and Remarkable Stabilization of dsDNA
|
0
|
0
|
0
|
0
|
22
|
14
|
0
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Polyglycine II Nanosheets: Supramolecular Antivirals?
|
0
|
0
|
0
|
0
|
11
|
10
|
0
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Polysaccharide Microarrays for Polysaccharide-Platelet-Derived-Growth-Factor Interaction Studies
|
0
|
0
|
0
|
0
|
33
|
22
|
1
|
23
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Porphyrin Derivatives for Telomere Binding and Telomerase Inhibition
|
0
|
0
|
0
|
0
|
57
|
50
|
7
|
57
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Post-translational Covalent Labeling Reveals Heterogeneous Mobility of Individual G Protein-Coupled Receptors in Living Cells
|
0
|
0
|
0
|
0
|
49
|
30
|
5
|
35
|
8
|
0
|
1
|
0
|
0
|
0
|
|
Posttranslational Modification of Proteins: Expanding Nature's Inventory. By Christopher T. Walsh.
|
0
|
0
|
0
|
0
|
29
|
13
|
4
|
17
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Potent Inhibitors of LXXLL-Based Protein-Protein Interactions
|
0
|
0
|
0
|
0
|
48
|
29
|
4
|
33
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Potent and Selective Inhibition of Class II α-D-Mannosidase Activity by a Bicyclic Sulfonium Salt
|
0
|
0
|
0
|
0
|
26
|
13
|
0
|
13
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Potentiometric Detection of Single Nucleotide Polymorphism by Using a Genetic Field-effect transistor
|
0
|
0
|
0
|
0
|
42
|
25
|
2
|
27
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Predicting the Nature and Timing of Epimerisation on a Modular Polyketide Synthase
|
0
|
0
|
0
|
0
|
45
|
95
|
19
|
114
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Preliminary Characterization of Light Harvesting in E. coli DNA Photolyase
|
0
|
0
|
0
|
0
|
15
|
11
|
0
|
11
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Preliminary Studies on the In Silico Evolution of Biochemical Networks
|
0
|
0
|
0
|
0
|
49
|
19
|
6
|
25
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Preparation and Antimalarial Activities of “Trioxaquines”, New Modular Molecules with a Trioxane Skeleton Linked to a 4-Aminoquinoline
|
0
|
0
|
0
|
0
|
15
|
11
|
1
|
12
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Preparation of Cyclo-Phen-Type Ligands: Chelators of Metal Ions as Potential Therapeutic Agents in the Treatment of Neurodegenerative Diseases
|
0
|
0
|
0
|
0
|
23
|
15
|
3
|
18
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Preparation of Symmetrical and Unsymmetrical DNA-Protein Conjugates with DNA as a Molecular Scaffold
|
0
|
0
|
0
|
0
|
24
|
13
|
1
|
14
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Prevention of Adhesion and Promotion of Pseudoislets Formation from a β-Cell Line by Fluorocarbon Emulsions
|
0
|
0
|
0
|
0
|
7
|
8
|
2
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview
|
0
|
0
|
0
|
0
|
0
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview
|
0
|
0
|
0
|
0
|
0
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview
|
0
|
0
|
0
|
0
|
0
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 1/2003
|
0
|
0
|
0
|
0
|
2
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 1/2004
|
0
|
0
|
0
|
0
|
1
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 1/2005
|
0
|
0
|
0
|
0
|
7
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 1/2006
|
0
|
0
|
0
|
0
|
8
|
4
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 10/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 10/2003
|
0
|
0
|
0
|
0
|
2
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 10/2004
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 10/2005
|
0
|
0
|
0
|
0
|
1
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 10/2006
|
0
|
0
|
0
|
0
|
3
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 11/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 11/2003
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 11/2004
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 11/2005
|
0
|
0
|
0
|
0
|
3
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 11/2006
|
0
|
0
|
0
|
0
|
2
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 12/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 12/2003
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 12/2004
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 12/2005
|
0
|
0
|
0
|
0
|
3
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 12/2006
|
0
|
0
|
0
|
0
|
7
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 2-3/2003
|
0
|
0
|
0
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 2/2004
|
0
|
0
|
0
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 2/2005
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 2/2006
|
0
|
0
|
0
|
0
|
6
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 2/2007
|
0
|
0
|
0
|
0
|
12
|
17
|
0
|
17
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 3/2004
|
0
|
0
|
0
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 3/2005
|
0
|
0
|
0
|
0
|
7
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 3/2006
|
0
|
0
|
0
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 3/2007
|
0
|
0
|
0
|
0
|
15
|
74
|
0
|
74
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 4/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 4/2003
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 4/2004
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 4/2005
|
0
|
0
|
0
|
0
|
2
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 4/2006
|
0
|
0
|
0
|
0
|
9
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 4/2007
|
0
|
0
|
0
|
0
|
28
|
65
|
0
|
65
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 5/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 5/2003
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 5/2004
|
0
|
0
|
0
|
0
|
5
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 5/2005
|
0
|
0
|
0
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 5/2006
|
0
|
0
|
0
|
0
|
10
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Preview: ChemBioChem 5/2007
|
0
|
0
|
0
|
0
|
20
|
49
|
0
|
49
|
0
|
0
|
0
|
0
|
0
|
0
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Preview: ChemBioChem 6/2002
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1
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2
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Preview: ChemBioChem 6/2003
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Preview: ChemBioChem 6/2004
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3
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1
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Preview: ChemBioChem 6/2005
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4
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2
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2
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Preview: ChemBioChem 6/2006
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2
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1
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1
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Preview: ChemBioChem 6/2007
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7
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48
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48
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Preview: ChemBioChem 7/2002
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Preview: ChemBioChem 7/2003
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Preview: ChemBioChem 7/2004
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5
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1
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Preview: ChemBioChem 7/2005
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Preview: ChemBioChem 7/2006
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8
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7
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7
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Preview: ChemBioChem 7/2007
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14
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16
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16
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Preview: ChemBioChem 8/2002
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1
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Preview: ChemBioChem 8/2003
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2
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Preview: ChemBioChem 8/2004
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Preview: ChemBioChem 8/2005
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3
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1
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Preview: ChemBioChem 8/2006
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1
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3
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3
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0
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Preview: ChemBioChem 9/2002
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1
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1
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0
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Preview: ChemBioChem 9/2003
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1
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0
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Preview: ChemBioChem 9/2004
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0
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0
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0
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0
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1
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Preview: ChemBioChem 9/2005
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0
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0
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0
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0
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2
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0
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0
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0
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Preview: ChemBioChem 9/2006
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0
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0
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0
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0
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1
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1
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0
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1
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0
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0
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0
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0
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0
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0
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|
Prion Diseases: From Molecular Biology to Intervention Strategies
|
0
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0
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0
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0
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57
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36
|
11
|
47
|
16
|
0
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0
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0
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0
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0
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Prion-Protein-Specific Aptamer Reduces PrPSc Formation
|
0
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0
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0
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0
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39
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30
|
2
|
32
|
8
|
0
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0
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0
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0
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0
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Probing Biomolecular Interactions of Glutathione Transferase M2-2 by using Peptide Phage Display
|
0
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0
|
0
|
0
|
10
|
7
|
0
|
7
|
0
|
0
|
0
|
0
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0
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0
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Probing Lectin and Sperm with Carbohydrate-Modified Quantum Dots
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0
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0
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0
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0
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68
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51
|
7
|
58
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5
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0
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0
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0
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0
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0
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Probing Protein-Carbohydrate Interactions with Microarrays of Synthetic Oligosaccharides
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0
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0
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0
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0
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36
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43
|
3
|
46
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4
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0
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0
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0
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0
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0
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Probing the Binding Entropy of Ligand-Protein Interactions by NMR
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0
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0
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0
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0
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38
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41
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14
|
55
|
4
|
0
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0
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0
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0
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0
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Probing the Ligand-Binding Specificity and Analyzing the Folding State of SPOT-Synthesized FBP28 WW Domain Variants
|
0
|
0
|
0
|
0
|
28
|
18
|
1
|
19
|
1
|
0
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0
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0
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0
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0
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|
Probing the Molecular Basis of Protein Function through Chemistry
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0
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0
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0
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0
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17
|
4
|
3
|
7
|
14
|
0
|
0
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0
|
0
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0
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|
Probing the Proteolytic Stability of β-Peptides Containing α-Fluoro- and α-Hydroxy-β-Amino Acids
|
0
|
0
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0
|
0
|
23
|
25
|
2
|
27
|
8
|
0
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0
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0
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0
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0
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|
Production of Lewis x Tetrasaccharides by Metabolically Engineered Escherichia coli
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0
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0
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0
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0
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33
|
19
|
3
|
22
|
2
|
0
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0
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0
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0
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0
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|
Production of the Tubulin Destabilizer Disorazol in Sorangium cellulosum: Biosynthetic Machinery and Regulatory Genes
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0
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0
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0
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0
|
94
|
64
|
18
|
82
|
8
|
0
|
0
|
0
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0
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0
|
|
Proline-Directed Random-Coil Chemical Shift Values as a Tool for the NMR Assignment of the Tau Phosphorylation Sites
|
0
|
0
|
0
|
0
|
3
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Proline-Directed Random-Coil Chemical Shift Values as a Tool for the NMR Assignment of the Tau Phosphorylation Sites
|
0
|
0
|
0
|
0
|
24
|
15
|
3
|
18
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Proofreading Activity of Pfu Thermostable DNA Polymerase on a 6-O-Methylguanine-Containing Template Monitored by ESI-FTICR Mass Spectrometry
|
0
|
0
|
0
|
0
|
8
|
3
|
0
|
3
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Protease Inhibitors Formed In Situ from Copper and Tridentate Chelates: A Generalized Approach towards Metal-Based Pharmaceuticals
|
0
|
0
|
0
|
0
|
15
|
11
|
0
|
11
|
2
|
0
|
0
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0
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0
|
0
|
|
Protective Activities of Some Phenolic 1,3-Diketones against Lipid Peroxidation: Possible Involvement of the 1,3-Diketone Moiety
|
0
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0
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0
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0
|
30
|
11
|
2
|
13
|
4
|
0
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0
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0
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0
|
0
|
|
Protein Chemistry on the Surface of Living Cells
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0
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0
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0
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0
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90
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52
|
7
|
59
|
19
|
0
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1
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0
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0
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0
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|
Protein Degradation Vol. 2: The Ubiquitin-Proteasome System. Edited by R. John Mayer, Aaron J. Ciechanover and Martin Rechsteiner.
|
0
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0
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0
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0
|
5
|
3
|
0
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3
|
0
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0
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0
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0
|
0
|
0
|
|
Protein Flexibility and Ligand Rigidity: A Thermodynamic and Kinetic Study of ITAM-Based Ligand Binding to Syk Tandem SH2
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0
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0
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0
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0
|
40
|
36
|
5
|
41
|
1
|
0
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0
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0
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0
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0
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|
Protein Folding Transition States: Elicitation of Hammond Effects by 2,2,2-Trifluoroethanol
|
0
|
0
|
0
|
0
|
10
|
7
|
0
|
7
|
2
|
0
|
0
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0
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0
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0
|
|
Protein Function Microarrays Based on Self-Immobilizing and Self-Labeling Fusion Proteins
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0
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0
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0
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0
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149
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80
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20
|
100
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18
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0
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1
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0
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0
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0
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|
Protein Stabilisation by Compatible Solutes: Effect of Mannosylglycerate on Unfolding Thermodynamics and Activity of Ribonuclease A
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0
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0
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0
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0
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18
|
8
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1
|
9
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3
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0
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0
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0
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0
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0
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|
Protein Structure Prediction: Concepts and Applications. Anna Tramontano.
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0
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0
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0
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0
|
18
|
5
|
0
|
5
|
2
|
0
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0
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0
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0
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0
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|
Protein Targeting (Nobel Lecture)
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0
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0
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0
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0
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98
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55
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0
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55
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23
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0
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0
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0
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0
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0
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|
Protein-Carbohydrate Interactions in Infectious Diseases. Edited by Carole A. Bewley.
|
0
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0
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0
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0
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30
|
37
|
7
|
44
|
5
|
0
|
0
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0
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0
|
0
|
|
Protein-Detecting Microarrays: Current Accomplishments and Requirements
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0
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0
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0
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0
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159
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133
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4
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137
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19
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0
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1
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0
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0
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0
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|
Protein-Lipid Interactions: From Membrane Domains to Cellular Networks. Edited by Lukas K. Tamm.
|
0
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0
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0
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0
|
2
|
1
|
0
|
1
|
0
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0
|
0
|
0
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0
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0
|
|
Protein-Structure Prediction by Recombination of Fragments
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0
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0
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0
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0
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48
|
30
|
2
|
32
|
14
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0
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0
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0
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0
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0
|
|
Proteins: Structure and Function. By David Whitford.
|
0
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0
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0
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0
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24
|
8
|
0
|
8
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Protonation Patterns in Tetracycline:Tet Repressor Recognition: Simulations and Experiments
|
0
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0
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0
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0
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29
|
16
|
0
|
16
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Pseudo 3D Single-Walled Carbon Nanotube Film for BSA-Free Protein Chips
|
0
|
0
|
0
|
0
|
1
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Pseudo 3D Single-Walled Carbon Nanotube Film for BSA-Free Protein Chips
|
0
|
0
|
0
|
0
|
22
|
23
|
2
|
25
|
1
|
0
|
0
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0
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0
|
0
|
|
Pseudo-Peptides in Drug Discovery. Edited by Peter E. Nielsen.
|
0
|
0
|
0
|
0
|
4
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Pseudoazurin-Nitrite Reductase Interactions
|
0
|
0
|
0
|
0
|
21
|
11
|
0
|
11
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Pure and Scrambled Self-Aggregates Prepared with Zinc Analogues of Bacteriochlorophylls c and d
|
0
|
0
|
0
|
0
|
10
|
5
|
1
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Purine-Based Inhibitors of Inositol-1,4,5-trisphosphate-3-kinase
|
0
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0
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0
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0
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31
|
12
|
3
|
15
|
7
|
0
|
0
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0
|
0
|
0
|
|
Pyrenemethyl ara-Uridine-2′-carbamate: A Strong Interstrand Excimer in the Major Groove of a DNA Duplex
|
0
|
0
|
0
|
0
|
18
|
17
|
0
|
17
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Quantification of the Raf-C1 Interaction With Solid-Supported Bilayers
|
0
|
0
|
0
|
0
|
9
|
9
|
2
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Quantum Dots As A Visual Aid For Screening Bead-Bound Combinatorial Libraries
|
0
|
0
|
0
|
0
|
40
|
24
|
3
|
27
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Quantum Dots Protected with Tiopronin: A New Fluorescence System for Cell-Biology Studies
|
0
|
0
|
0
|
0
|
42
|
35
|
8
|
43
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Quantum-Dot Aptamer Beacons for the Detection of Proteins
|
0
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0
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0
|
0
|
172
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122
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17
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139
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14
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0
|
0
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0
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0
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0
|
|
Quaternary Ammonium Zinc Phthalocyanine: Inhibiting Telomerase by Stabilizing G quadruplexes and Inducing G-Quadruplex Structure Transition and Formation
|
0
|
0
|
0
|
0
|
49
|
49
|
0
|
49
|
5
|
0
|
0
|
0
|
0
|
0
|
|
REPLACE: A Strategy for Iterative Design of Cyclin-Binding Groove Inhibitors
|
0
|
0
|
0
|
0
|
83
|
67
|
7
|
74
|
8
|
0
|
1
|
0
|
0
|
0
|
|
RNA Abasic Sites: Preparation and Trans-Lesion Synthesis by HIV-1 Reverse Transcriptase
|
0
|
0
|
0
|
0
|
24
|
14
|
2
|
16
|
1
|
0
|
0
|
0
|
0
|
0
|
|
RNA Interference and Small Interfering RNAs
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0
|
0
|
0
|
0
|
192
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95
|
12
|
107
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44
|
0
|
1
|
0
|
0
|
0
|
|
RNA as a Drug Target: The Case of Aminoglycosides
|
0
|
0
|
0
|
0
|
44
|
34
|
8
|
42
|
5
|
0
|
0
|
0
|
0
|
0
|
|
RNA-Interference-Based Silencing of Mammalian Gene Expression
|
0
|
0
|
0
|
0
|
12
|
10
|
0
|
10
|
4
|
0
|
0
|
0
|
0
|
0
|
|
RNA-Templated Chemistry in Cells: Discrimination of Escherichia, Shigella and Salmonella Bacterial Strains With a New Two-Color FRET Strategy
|
0
|
0
|
0
|
0
|
43
|
66
|
18
|
84
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Rapid Discovery of Potent Sulfotransferase Inhibitors by Diversity-Oriented Reaction in Microplates Followed by in situ Screening
|
0
|
0
|
0
|
0
|
41
|
28
|
4
|
32
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Rapid Diversity-Oriented Synthesis in Microtiter Plates for In Situ Screening of HIV Protease Inhibitors
|
0
|
0
|
0
|
0
|
73
|
67
|
7
|
74
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Rapid Enzymatic Isomerization of 12-Oxophytodienoic Acid in the Gut of Lepidopteran Larvae
|
0
|
0
|
0
|
0
|
58
|
70
|
11
|
81
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Rapid Identification of Potent Nonpeptidic Serine Protease Inhibitors
|
0
|
0
|
0
|
0
|
76
|
50
|
5
|
55
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Rapid and Quantitative Cyclization of Multiple Peptide Loops onto Synthetic Scaffolds for Structural Mimicry of Protein Surfaces
|
0
|
0
|
0
|
0
|
40
|
28
|
2
|
30
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Ras-Mediated Cleavage of a GTP Analogue by a Novel Mechanism
|
0
|
0
|
0
|
0
|
15
|
10
|
2
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Ratcheting Up vir Gene Expression in Agrobacterium tumefaciens: Coiled Coils in Histidine Kinase Signal Transduction
|
0
|
0
|
0
|
0
|
10
|
4
|
2
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Rational Manipulation of Carrier-Domain Geometry in Nonribosomal Peptide Synthetases
|
0
|
0
|
0
|
0
|
69
|
91
|
2
|
93
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Rational Saccharide Extension by Using the Natural Product Glycosyltransferase LanGT4
|
0
|
0
|
0
|
0
|
9
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Reaching the Target: Small Molecules Aim to Probe Barrier Quality
|
0
|
0
|
0
|
0
|
6
|
17
|
1
|
18
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Reaction of Cytidine Nucleotides with Cyanoacetylene: Support for the Intermediacy of Nucleoside-2′,3′-cyclic Phosphates in the Prebiotic Synthesis of RNA
|
0
|
0
|
0
|
0
|
19
|
11
|
3
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Reactivity of Intein Thioesters: Appending a Functional Group to a Protein
|
0
|
0
|
0
|
0
|
118
|
111
|
16
|
127
|
15
|
0
|
0
|
0
|
0
|
0
|
|
Real-Time Monitoring of in vitro Transcriptional RNA by Using Fluorescence Correlation Spectroscopy
|
0
|
0
|
0
|
0
|
10
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Real-Time Polymerase Chain Reaction
|
0
|
0
|
0
|
0
|
431
|
242
|
39
|
281
|
91
|
0
|
0
|
1
|
0
|
0
|
|
Real-time Detection of Nucleotide Incorporation During Complementary DNA Strand Synthesis
|
0
|
0
|
0
|
0
|
25
|
12
|
0
|
12
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Reassembled Biosynthetic Pathway for Large-Scale Carbohydrate Synthesis: α-Gal Epitope Producing “Superbug”
|
0
|
0
|
0
|
0
|
2
|
7
|
3
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
RebG- and RebM-Catalyzed Indolocarbazole Diversification
|
0
|
0
|
0
|
0
|
50
|
43
|
2
|
45
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Receptor-Dependence of the Transcription Read-Out in a Small-Molecule Three-Hybrid System
|
0
|
0
|
0
|
0
|
22
|
21
|
4
|
25
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Recognition of Planar and Nonplanar Ligands in the Malachite Green-RNA Aptamer Complex
|
0
|
0
|
0
|
0
|
82
|
38
|
11
|
49
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Recognition of Remote Mismatches by DNA Polymerases
|
0
|
0
|
0
|
0
|
24
|
8
|
0
|
8
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Recognition on the Nanoscale of a DNA Sequence by an Inorganic Crystal Surface
|
0
|
0
|
0
|
0
|
23
|
22
|
3
|
25
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Recombinant Production of Human Microsomal Cytochrome P450 2D6 in the Methylotrophic Yeast Pichia pastoris
|
0
|
0
|
0
|
0
|
39
|
14
|
2
|
16
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Redox Potential of Azobenzene as an Amino Acid Residue in Peptides
|
0
|
0
|
0
|
0
|
47
|
65
|
1
|
66
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Redox Potentials of Methanophenazine and CoB-S-S-CoM, Factors Involved in Electron Transport in Methanogenic Archaea
|
0
|
0
|
0
|
0
|
22
|
15
|
6
|
21
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Reevaluation of the Violacein Biosynthetic Pathway and its Relationship to Indolocarbazole Biosynthesis
|
0
|
0
|
0
|
0
|
97
|
62
|
7
|
69
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Regio- and Stereoselective Intermolecular Oxidative Phenol Coupling in Kotanin Biosynthesis by Aspergillus Niger
|
0
|
0
|
0
|
0
|
47
|
105
|
8
|
113
|
3
|
3
|
0
|
0
|
0
|
0
|
|
Regions of Tau Implicated in the Paired Helical Fragment Core as Defined by NMR
|
0
|
0
|
0
|
0
|
20
|
10
|
0
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Regioselective Carbon-Carbon Bond Formation in Proteins with Palladium Catalysis; New Protein Chemistry by Organometallic Chemistry
|
0
|
0
|
0
|
0
|
60
|
64
|
8
|
72
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Regioselective Carbon-Carbon Bond Formation in Proteins with Palladium Catalysis; New Protein Chemistry by Organometallic Chemistry
|
0
|
0
|
0
|
0
|
30
|
138
|
28
|
166
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Regulating Enzyme Activities in a Multiple-Enzyme Complex
|
0
|
0
|
0
|
0
|
10
|
13
|
0
|
13
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Regulation of Exocytosis in Chromaffin Cells by Trans-Insertion of Lysophosphatidylcholine and Arachidonic Acid into the Outer Leaflet of the Cell Membrane
|
0
|
0
|
0
|
0
|
32
|
27
|
8
|
35
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Regulation of G Protein- Coupled Receptor Function and Expression Edited by Jeffrey L. Benovic
|
0
|
0
|
0
|
0
|
5
|
1
|
1
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Regulation of Transcription by Synthetic DNA-Bending Agents
|
0
|
0
|
0
|
0
|
46
|
36
|
10
|
46
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Relevance of Atypical Protein Kinase C Isotypes to the Drug Discovery Process
|
0
|
0
|
0
|
0
|
19
|
11
|
3
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Remarkable Stabilization of Duplex DNA Containing an Abasic Site by Non-Nucleosidic Phenanthroline and Pyrene Building Blocks
|
0
|
0
|
0
|
0
|
13
|
12
|
3
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Remote Interactions Explain the Unusual Regioselectivity of Lipase from Pseudomonas cepacia toward the Secondary Hydroxyl of 2′-Deoxynucleosides
|
0
|
0
|
0
|
0
|
31
|
12
|
0
|
12
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Replacement of Isobutyl by Trifluoromethyl in Pepstatin A Selectively Affects Inhibition of Aspartic Proteinases
|
0
|
0
|
0
|
0
|
34
|
23
|
1
|
24
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Replacement of Natural Cofactors by Selected Hydrogen Peroxide Donors or Organic Peroxides Results in Improved Activity for CYP3A4 and CYP2D6
|
0
|
0
|
0
|
0
|
49
|
25
|
6
|
31
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Replacement of the Intervening Amino Acid Sequence of a Syk-Binding Diphosphopeptide by a Nonpeptide Spacer with Preservation of High Affinity
|
0
|
0
|
0
|
0
|
11
|
8
|
1
|
9
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Residue- and Sequence-Selective Binding of Nonaromatic Dipeptides by Bis(β-cyclodextrin) with a Functional Tether
|
0
|
0
|
0
|
0
|
9
|
10
|
0
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Reverse Prenyltransferase in the Biosynthesis of Fumigaclavine C in Aspergillus fumigatus: Gene Expression, Purification, and Characterization of Fumigaclavine C Synthase FGAPT1
|
0
|
0
|
0
|
0
|
48
|
26
|
0
|
26
|
7
|
0
|
0
|
1
|
0
|
0
|
|
Reversible Acetonitrile-Induced Inactivation/Activation of Thermolysin
|
0
|
0
|
0
|
0
|
9
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Reversible Inactivation of the CG Specific SssI DNA (Cytosine-C5)-Methyltransferase with a Photocleavable Protecting Group
|
0
|
0
|
0
|
0
|
104
|
143
|
19
|
162
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Reversible Sequential-Binding Probe Receptor-Ligand Interactions in Single Cells
|
0
|
0
|
0
|
0
|
38
|
20
|
6
|
26
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Ring-Closing Metathesis of C-Terminal Allylglycine Residues with an N-Terminal β-Vinyl-Substituted Phosphotyrosyl Mimetic as an Approach to Novel Grb2 SH2 Domain-Binding Macrocycles
|
0
|
0
|
0
|
0
|
28
|
19
|
0
|
19
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Ringing in the New
|
0
|
0
|
0
|
0
|
18
|
9
|
6
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Role of DNA Sequence in the Binding Specificity of Synthetic Basic-Helix-Loop-Helix Domains
|
0
|
0
|
0
|
0
|
27
|
23
|
5
|
28
|
1
|
0
|
0
|
0
|
0
|
0
|
|
SMAF-1 Inhibits the APC/β-Catenin Pathway and Shows Properties Similar to Those of the Tumor Suppressor Protein APC
|
0
|
0
|
0
|
0
|
19
|
7
|
1
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
SPR Studies of Carbohydrate-Protein Interactions: Signal Enhancement of Low-Molecular-Mass Analytes by Organoplatinum(II)-Labeling
|
0
|
0
|
0
|
0
|
57
|
32
|
1
|
33
|
6
|
0
|
0
|
0
|
0
|
0
|
|
SUBJECT INDEX: ChemBioChem 12/2002
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Satellite Hole Spectroscopy of Thrombin-Aptamer Complexes
|
0
|
0
|
0
|
0
|
18
|
21
|
0
|
21
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Scanning Force Microscopy Study on a Single-Stranded DNA: The Genome of Parvovirus B19
|
0
|
0
|
0
|
0
|
13
|
4
|
2
|
6
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Scanning Force Microscopy of Artificial Membranes
|
0
|
0
|
0
|
0
|
28
|
22
|
6
|
28
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Searching Sequence Space: Two Different Approaches to Dihydrofolate Reductase Catalysis
|
0
|
0
|
0
|
0
|
40
|
22
|
5
|
27
|
10
|
0
|
0
|
1
|
0
|
0
|
|
Seeing Is Believing: Peptide-Based Fluorescent Sensors of Protein Tyrosine Kinase Activity
|
0
|
0
|
0
|
0
|
161
|
335
|
25
|
360
|
31
|
0
|
1
|
0
|
0
|
0
|
|
Selection of D-Amino-Acid Peptides That Bind to Alzheimer's Disease Amyloid Peptide Aβ1-42 by Mirror Image Phage Display
|
0
|
0
|
0
|
0
|
64
|
28
|
3
|
31
|
9
|
0
|
0
|
1
|
0
|
0
|
|
Selection of Hammerhead Ribozyme Variants with Low Mg2+ Requirement: Importance of Stem-Loop II
|
0
|
0
|
0
|
0
|
11
|
8
|
2
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Selection of Metalloenzymes by Catalytic Activity Using Phage Display and Catalytic Elution
|
0
|
0
|
0
|
0
|
15
|
9
|
2
|
11
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Selection of Small-Molecule Mediators of the RNA Regulation of PKR, the RNA-Dependent Protein Kinase
|
0
|
0
|
0
|
0
|
9
|
12
|
0
|
12
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Selection of an Active Enzyme by Phage Display on the Basis of the Enzyme's Catalytic Activity in vivo
|
0
|
0
|
0
|
0
|
34
|
14
|
2
|
16
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Selective Cleavage of Unpaired Uridines with a Tyrosine-Cyclen Conjugate
|
0
|
0
|
0
|
0
|
5
|
4
|
2
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Selective Estrogen-Receptor Modulators (SERMs) in the Cyclopentadienylrhenium Tricarbonyl Series: Synthesis and Biological Behaviour
|
0
|
0
|
0
|
0
|
18
|
13
|
1
|
14
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Selective Hydroxylation of Highly Branched Fatty Acids and their Derivatives by CYP102A1 from Bacillus megaterium
|
0
|
0
|
0
|
0
|
43
|
27
|
1
|
28
|
8
|
0
|
0
|
1
|
0
|
0
|
|
Selective Incorporation of 19F-Labeled Trp Side Chains for NMR-Spectroscopy-Based Ligand-Protein Interaction Studies
|
0
|
0
|
0
|
0
|
17
|
18
|
1
|
19
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Selective Inhibition of HIV-1 Reverse Transcriptase (HIV-1 RT) RNase H by Small RNA Hairpins and Dumbbells
|
0
|
0
|
0
|
0
|
27
|
10
|
1
|
11
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Selective Labeling of Proteins by Using Protein Farnesyltransferase
|
0
|
0
|
0
|
0
|
96
|
176
|
24
|
200
|
12
|
0
|
0
|
0
|
0
|
0
|
|
Selective Protein Degradation by Ligand-Targeted Enzymes: Towards the Creation of Catalytic Antagonists
|
0
|
0
|
0
|
0
|
7
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Selective Stabilization of Triple-Helical DNA by Diazoniapolycyclic Intercalators
|
0
|
0
|
0
|
0
|
29
|
18
|
1
|
19
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Selective Staudinger Modification of Proteins Containing p-Azidophenylalanine
|
0
|
0
|
0
|
0
|
82
|
34
|
14
|
48
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Selenocysteine Derivatives for Chemoselective Ligations
|
0
|
0
|
0
|
0
|
44
|
30
|
3
|
33
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Selenolthiol and Dithiol C-Terminal Tetrapeptide Motifs for One-Step Purification and Labeling of Recombinant Proteins Produced in E. coli
|
0
|
0
|
0
|
0
|
48
|
43
|
7
|
50
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Self-Assembled Small-Molecule Microarrays for Protease Screening and Profiling
|
0
|
0
|
0
|
0
|
152
|
104
|
10
|
114
|
9
|
0
|
0
|
1
|
0
|
0
|
|
Semisynthesis and Characterization of the First Analogues of Pro-Neuropeptide Y
|
0
|
0
|
0
|
0
|
21
|
13
|
4
|
17
|
3
|
0
|
1
|
0
|
0
|
0
|
|
Semisynthesis of Ht31(493-515): Involvement of PKA-Anchoring Proteins in the Regulation of the cAMP-Dependent Chloride Current in Heart Cells
|
0
|
0
|
0
|
0
|
5
|
3
|
0
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Sequence-Specific DNA Binding Agents. Edited by Michael Waring.
|
0
|
0
|
0
|
0
|
22
|
52
|
7
|
59
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Sequence-Specific DNA Recognition by Monomeric bZIP Basic Regions Equipped with a Tripyrrole Unit on the N-Terminal Side. Towards the Development of Synthetic Mimics of Skn-1
|
0
|
0
|
0
|
0
|
14
|
13
|
2
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Serum Albumin-Catalyzed Trigger System by Using a Tandem Kemp Elimination/β-Elimination Reaction
|
0
|
0
|
0
|
0
|
10
|
4
|
1
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Shape Complementarity, Binding-Site Dynamics, and Transition State Stabilization: A Theoretical Study of Diels-Alder Catalysis by Antibody 1E9
|
0
|
0
|
0
|
0
|
10
|
6
|
3
|
9
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Shotgun Cloning and Heterologous Expression of the Patellamide Gene Cluster as a Strategy to Achieving Sustained Metabolite Production
|
0
|
0
|
0
|
0
|
60
|
42
|
1
|
43
|
17
|
0
|
0
|
0
|
0
|
0
|
|
Signaling Aptamers for Monitoring Enzymatic Activity and for Inhibitor Screening
|
0
|
0
|
0
|
0
|
12
|
20
|
1
|
21
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Signaling Effects of Demethylasterriquinone B1, a Selective Insulin Receptor Modulator
|
0
|
0
|
0
|
0
|
28
|
9
|
2
|
11
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Silica Pattern Formation in Diatoms: Species-Specific Polyamine Biosynthesis
|
0
|
0
|
0
|
0
|
70
|
56
|
2
|
58
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Simplified Synthetic TMC-95A/B Analogues Retain the Potency of Proteasome Inhibitory Activity
|
0
|
0
|
0
|
0
|
11
|
11
|
0
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Single Amino Acid Substitutions Alter the Efficiency of Docking in Modular Polyketide Biosynthesis
|
0
|
0
|
0
|
0
|
27
|
23
|
1
|
24
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Single-Molecule Study Reveals a Complex E. coli RNA Polymerase
|
0
|
0
|
0
|
0
|
13
|
5
|
2
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Site-Directed Mutagenesis of Tyr354 in Geobacillus stearothermophilus Alanine Racemase Identifies a Role in Controlling Substrate Specificity and a Possible Role in the Evolution of Antibiotic Resistance
|
0
|
0
|
0
|
0
|
6
|
4
|
0
|
4
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Site-Selective DNA Hydrolysis by CeIV-EDTA with the Use of One Oligonucleotide Additive Bearing Two Monophosphates
|
0
|
0
|
0
|
0
|
10
|
8
|
1
|
9
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Cleavage of the HIV-1 TAR RNA by a Hydroxysalen-Copper(III) Complex
|
0
|
0
|
0
|
0
|
7
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Cleavage - A Model System for the Identification of Lipid-Modified Glutamate Residues in Proteins
|
0
|
0
|
0
|
0
|
14
|
3
|
0
|
3
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Fluorescent and Affinity Labelling of RNA by Using a Small Engineered Twin Ribozyme
|
0
|
0
|
0
|
0
|
18
|
6
|
0
|
6
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Functionalization of Proteins by Organopalladium Reactions
|
0
|
0
|
0
|
0
|
120
|
264
|
38
|
302
|
13
|
1
|
0
|
0
|
0
|
0
|
|
Site-Specific Immobilization of Genetically Engineered Variants of Candida antarctica Lipase B
|
0
|
0
|
0
|
0
|
75
|
58
|
9
|
67
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Incorporation of Unnatural Amino Acids into Proteins
|
0
|
0
|
0
|
0
|
55
|
46
|
8
|
54
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Labelling of Proteins with a Rigid Lanthanide-Binding Tag
|
0
|
0
|
0
|
0
|
94
|
70
|
16
|
86
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Modification of Epstein-Barr Virus-Encoded RNA 1 with N2-Benzylguanosine Limits the Binding Sites Occupied by PKR
|
0
|
0
|
0
|
0
|
21
|
9
|
1
|
10
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific Multivalent Carbohydrate Labeling of Quantum Dots and Magnetic Beads
|
0
|
0
|
0
|
0
|
49
|
28
|
6
|
34
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Site-Specific in vivo Labeling of Proteins for NMR Studies
|
0
|
0
|
0
|
0
|
45
|
34
|
5
|
39
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Small-Molecule Binding to the Nonquadruplex Form of the Human Telomeric Sequence
|
0
|
0
|
0
|
0
|
4
|
7
|
0
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Small-Molecule Inhibitors and Probes for Ubiquitin- and Ubiquitin-Like-Specific Proteases
|
0
|
0
|
0
|
0
|
69
|
45
|
13
|
58
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Small-Molecule Kinase-Inhibitor Target Assessment
|
0
|
0
|
0
|
0
|
90
|
58
|
6
|
64
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Small-Molecule Screening and Profiling by Using Automated Microscopy
|
0
|
0
|
0
|
0
|
61
|
47
|
11
|
58
|
14
|
0
|
0
|
1
|
0
|
0
|
|
Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEGylated Antisense Oligonucleotides Containing Acid-Labile Linkages
|
0
|
0
|
0
|
0
|
65
|
48
|
5
|
53
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Solid State NMR Investigation of the Interaction between Biomimetic Lipid Bilayers and de novo Designed Fusogenic Peptides
|
0
|
0
|
0
|
0
|
45
|
57
|
5
|
62
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Solid-Phase Synthesis and Biological Activity of a Thioether Analogue of Conotoxin G1
|
0
|
0
|
0
|
0
|
33
|
17
|
0
|
17
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Solid-Phase Synthesis of Double-Headed Epoxysuccinyl Activity-Based Probes for Selective Targeting of Papain Family Cysteine Proteases
|
0
|
0
|
0
|
0
|
21
|
13
|
2
|
15
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Solid-State Magic-Angle Spinning NMR of Outer-Membrane Protein G from Escherichia coli
|
0
|
0
|
0
|
0
|
44
|
21
|
5
|
26
|
6
|
0
|
2
|
0
|
0
|
0
|
|
Solid-State NMR of Matrix Metalloproteinase 12: An Approach Complementary to Solution NMR
|
0
|
0
|
0
|
0
|
49
|
56
|
7
|
63
|
20
|
0
|
0
|
0
|
0
|
0
|
|
Solution NMR Studies of an Intrinsically Unstructured Protein within a Dilute, 75 kDa Eukaryotic Protein Assembly; Probing the Practical Limits for Efficiently Assigning Polypeptide Backbone Resonances
|
0
|
0
|
0
|
0
|
52
|
25
|
8
|
33
|
6
|
0
|
1
|
0
|
0
|
0
|
|
Solution Structure and Stability of Tryptophan-Containing Nucleopeptide Duplexes
|
0
|
0
|
0
|
0
|
11
|
7
|
1
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Solution Structure of n-Type DNA Oligomers Possessing a Covalently Cross-Linked Watson-Crick Base Pair Model
|
0
|
0
|
0
|
0
|
5
|
7
|
1
|
8
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Solution Structure of Domain 6 from a Self-Splicing Group II Intron Ribozyme: A Mg2+ Binding Site is Located Close to the Stacked Branch Adenosine
|
0
|
0
|
0
|
0
|
155
|
181
|
13
|
194
|
13
|
0
|
1
|
0
|
0
|
0
|
|
Solution- and Crystal-Phase Covalent Modification of Lysozyme by a Purpose-Designed Organoruthenium Complex. A MALDI-TOF MS Study of its Metal Binding Sites
|
0
|
0
|
0
|
0
|
10
|
4
|
0
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Solution- and Solid-Phase Synthesis of the Polybasic Lipid-Modified C Termini of Rho A and K-Ras 4B
|
0
|
0
|
0
|
0
|
20
|
18
|
4
|
22
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Solvent Engineering Substantially Enhances the Chemoenzymatic Production of Surfactin
|
0
|
0
|
0
|
0
|
45
|
28
|
2
|
30
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Some Like It Hot: The Molecular Determinants of Protein Thermostability
|
0
|
0
|
0
|
0
|
8
|
9
|
2
|
11
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Sorting of Preproteins into Mitochondria
|
0
|
0
|
0
|
0
|
11
|
7
|
3
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Spatial and Temporal Sequence of Events in Cell Adhesion: From Molecular Recognition to Focal Adhesion Assembly
|
0
|
0
|
0
|
0
|
92
|
58
|
10
|
68
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Specific 3′-Terminal Modification of DNA with a Novel Nucleoside Analogue that Allows a Covalent Linkage of a Nuclear Localization Signal and Enhancement of DNA Stability
|
0
|
0
|
0
|
0
|
18
|
8
|
3
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Specific Interactions Between Sense and Complementary Peptides: The Basis for the Proteomic Code
|
0
|
0
|
0
|
0
|
40
|
25
|
4
|
29
|
10
|
0
|
0
|
1
|
0
|
0
|
|
Specific Interactions Between Sense and Complementary Peptides: The Basis for the Proteomic Code
|
0
|
0
|
0
|
0
|
7
|
5
|
2
|
7
|
1
|
0
|
0
|
1
|
0
|
0
|
|
Specificity Studies of Bacillus 1,3-1,4-β- Glucanases and Application to Glycosynthase-Catalyzed Transglycosylation
|
0
|
0
|
0
|
0
|
16
|
8
|
2
|
10
|
1
|
0
|
1
|
0
|
0
|
0
|
|
Spiegelmers: Biostable Aptamers
|
0
|
0
|
0
|
0
|
102
|
47
|
9
|
56
|
16
|
0
|
0
|
0
|
0
|
0
|
|
Spin Labels as a Tool to Identify and Characterize Protein-Ligand Interactions by NMR Spectroscopy
|
0
|
0
|
0
|
0
|
47
|
26
|
2
|
28
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Stabilisation of RNA Bulges by Oligonucleotide Complements Containing an Adenosine Analogue
|
0
|
0
|
0
|
0
|
3
|
8
|
0
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Stabilization of bzip Peptides through Incorporation of Fluorinated Aliphatic Residues
|
0
|
0
|
0
|
0
|
54
|
27
|
10
|
37
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Stepwise Solid-Phase Synthesis and Spontaneous Homodimerization of the Helix-Loop-Helix Protein Id3
|
0
|
0
|
0
|
0
|
15
|
6
|
3
|
9
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Stereochemical Course of Escherichia coli RNase H
|
0
|
0
|
0
|
0
|
7
|
4
|
1
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Stereoselective Incorporation of an Unsaturated Isoleucine Analogue into a Protein Expressed in E. coli
|
0
|
0
|
0
|
0
|
34
|
26
|
3
|
29
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Stereoselective Recognition of Monolayers of Cholesterol, ent-Cholesterol, and Epicholesterol by an Antibody
|
0
|
0
|
0
|
0
|
17
|
11
|
1
|
12
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Stereoselective Synthesis using Immobilized Diels-Alderase Ribozymes
|
0
|
0
|
0
|
0
|
12
|
10
|
0
|
10
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Stereoselectivity, Sequence Specificity and Mechanism of Action of the Azinomycin Epoxide
|
0
|
0
|
0
|
0
|
50
|
26
|
4
|
30
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Stereospecific Synthesis of Chiral 2,3-Dihydro-1,4-benzodithiine and Methyl-2,3-dihydro-1,4-benzodithiine Derivatives and their Toxic Effects on Trypanosoma brucei
|
0
|
0
|
0
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Sticky Proteins for Stem Cells
|
0
|
0
|
0
|
0
|
11
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Stochastic Sensing of TNT with a Genetically Engineered Pore
|
0
|
0
|
0
|
0
|
35
|
28
|
2
|
30
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Stochasticity of Manganese Superoxide Dismutase mRNA Expression in Breast Carcinoma Cells by Molecular Beacon Imaging
|
0
|
0
|
0
|
0
|
21
|
19
|
3
|
22
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Strategies for Facilitated Forward Chemical Genetics
|
0
|
0
|
0
|
0
|
40
|
25
|
5
|
30
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Strategies for the NMR-Based Identification and Optimization of Allosteric Protein Kinase Inhibitors
|
0
|
0
|
0
|
0
|
56
|
37
|
6
|
43
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Structural Analysis of the Capsular Polysaccharide from Campylobacter jejuni RM1221
|
0
|
0
|
0
|
0
|
67
|
55
|
0
|
55
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Structural Aspects of Adhesion to and Invasion of Host Cells by the Human Pathogen Listeria monocytogenes
|
0
|
0
|
0
|
0
|
22
|
14
|
8
|
22
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Structural Biology of Membrane Proteins. Edited by Reinhard Grisshammer and Susan K. Buchanan.
|
0
|
0
|
0
|
0
|
36
|
23
|
5
|
28
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Structural Changes of Cytochrome c552 from Thermus thermophilus Adsorbed on Anionic and Hydrophobic Surfaces Probed by FTIR and 2D-FTIR Spectroscopy
|
0
|
0
|
0
|
0
|
7
|
6
|
4
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Structural Insight Into Functional Aspects of Ribosomal RNA Targeting
|
0
|
0
|
0
|
0
|
13
|
15
|
0
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Structural Investigation of a High-Affinity MnII Binding Site in the Hammerhead Ribozyme by EPR Spectroscopy and DFT Calculations. Effects of Neomycin B on Metal-Ion Binding
|
0
|
0
|
0
|
0
|
17
|
12
|
2
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Structural Investigation of the HIV-1 Envelope Glycoprotein gp160 Cleavage Site 3: Role of Site-Specific Mutations
|
0
|
0
|
0
|
0
|
27
|
11
|
1
|
12
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Structural Investigation of the HIV-1 Envelope Glycoprotein gp160 Cleavage Site, 2: Relevance of an N-Terminal Helix
|
0
|
0
|
0
|
0
|
16
|
6
|
1
|
7
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Structural Models of the Photointermediates in the Rhodopsin Photocascade, Lumirhodopsin, Metarhodopsin I, and Metarhodopsin II
|
0
|
0
|
0
|
0
|
37
|
31
|
8
|
39
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Structural Modifications Enable Conserved Peptides to Fit into MHC Molecules thus Inducing Protection against Malaria
|
0
|
0
|
0
|
0
|
8
|
2
|
0
|
2
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Structural Recognition of Cholesterol-Ceramide Monolayers by a Specific Monoclonal Antibody
|
0
|
0
|
0
|
0
|
30
|
30
|
2
|
32
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Structural Reorganization of the Acetylcholine Binding Site of the Torpedo Nicotinic Receptor as Revealed by Dynamic Photoaffinity Labeling
|
0
|
0
|
0
|
0
|
12
|
9
|
2
|
11
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Structure Refinement of Cyclosporin A in Chloroform by Using RDCs Measured in a Stretched PDMS-Gel
|
0
|
0
|
0
|
0
|
38
|
23
|
3
|
26
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Structure and Biosynthesis of Myxochromides S1-3 in Stigmatella aurantiaca: Evidence for an Iterative Bacterial Type I Polyketide Synthase and for Module Skipping in Nonribosomal Peptide Biosynthesis
|
0
|
0
|
0
|
0
|
33
|
19
|
4
|
23
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Structure and Orientation of Ligands Bound to Membrane Proteins Are Reflected by Residual Dipolar Couplings in Solution NMR Measurements
|
0
|
0
|
0
|
0
|
8
|
10
|
0
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Structure and Redox Properties of the Haem Centre in the C357M Mutant of Cytochrome P450cam
|
0
|
0
|
0
|
0
|
38
|
16
|
3
|
19
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Structure of the Antimicrobial, Cationic Hexapeptide Cyclo(RRWWRF) and Its Analogues in Solution and Bound to Detergent Micelles
|
0
|
0
|
0
|
0
|
38
|
21
|
6
|
27
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Structure of the DNA Coiled Coil Formed by d(CGATATATATAT)
|
0
|
0
|
0
|
0
|
7
|
6
|
1
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Activity Studies in a Family of β-Hairpin Protein Epitope Mimetic Inhibitors of the p53-HDM2 Protein-Protein Interaction
|
0
|
0
|
0
|
0
|
97
|
58
|
24
|
82
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Activity Studies on the Corticotropin Releasing Factor Antagonist Astressin, leading to a Minimal Sequence necessary for Antagonistic Activity
|
0
|
0
|
0
|
0
|
30
|
9
|
2
|
11
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Aided Optimization of Kinase Inhibitors Derived from Alsterpaullone
|
0
|
0
|
0
|
0
|
30
|
22
|
3
|
25
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Based Design, Synthesis, and in vitro Evaluation of Nonpeptidic Neprilysin Inhibitors
|
0
|
0
|
0
|
0
|
22
|
11
|
1
|
12
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Based Enhancement of the First Anomeric Glucokinase
|
0
|
0
|
0
|
0
|
18
|
8
|
3
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Based Enzyme Engineering and Its Impact on In Vitro Glycorandomization
|
0
|
0
|
0
|
0
|
36
|
16
|
0
|
16
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Based Synthetic Mimicry of Discontinuous Protein Binding Sites: Inhibitors of the Interaction of Mena EVH1 Domain with Proline-Rich Ligands
|
0
|
0
|
0
|
0
|
35
|
18
|
3
|
21
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Structure-Function Analysis of the Soluble Glycoprotein, sGP, of Ebola Virus
|
0
|
0
|
0
|
0
|
93
|
59
|
11
|
70
|
15
|
0
|
0
|
0
|
0
|
0
|
|
Structures and Stabilities of Small DNA Dumbbells with Watson-Crick and Hoogsteen Base Pairs
|
0
|
0
|
0
|
0
|
8
|
7
|
0
|
7
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Studies on DNA Cleavage by Cytotoxic Pyrrole Alkaloids Reveal the Distinctly Different Behavior of Roseophilin and Prodigiosin Derivatives
|
0
|
0
|
0
|
0
|
6
|
7
|
1
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Study of the Hydrophobic Cavity of β-Cryptogein through Laser-Polarized Xenon NMR Spectroscopy
|
0
|
0
|
0
|
0
|
19
|
13
|
2
|
15
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Substrate Arrays as Enzyme Fingerprinting Tools
|
0
|
0
|
0
|
0
|
16
|
13
|
1
|
14
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Substrate Specificity of Mutants of the Hydroxynitrile Lyase from Manihot esculenta
|
0
|
0
|
0
|
0
|
22
|
10
|
1
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Subtype Selective Tetracycline Agonists and their Application for a Two-Stage Regulatory System
|
0
|
0
|
0
|
0
|
25
|
23
|
4
|
27
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Suicide Gene Therapy: Methods and Reviews. Edited by Caroline J. Springer.
|
0
|
0
|
0
|
0
|
2
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Sulfate Metabolism in Mycobacteria
|
0
|
0
|
0
|
0
|
98
|
81
|
10
|
91
|
17
|
0
|
0
|
0
|
0
|
0
|
|
Sunflower-Shaped Cyclodextrin-Conjugated Poly(ϵ-Lysine) Polyplex as a Controlled Intracellular Trafficking Device
|
0
|
0
|
0
|
0
|
21
|
13
|
0
|
13
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Surface Change of Ras Enabling Effector Binding Monitored in Real Time at Atomic Resolution
|
0
|
0
|
0
|
0
|
24
|
10
|
0
|
10
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation
|
0
|
0
|
0
|
0
|
99
|
83
|
0
|
83
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Surface Plasmon Resonance Evaluation of Various Aminoglycoside-RNA Hairpin Interactions Reveals Low Degree of Selectivity
|
0
|
0
|
0
|
0
|
38
|
14
|
4
|
18
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Surface-Functionalized Nanoparticle Library Yields Probes for Apoptotic Cells
|
0
|
0
|
0
|
0
|
83
|
49
|
4
|
53
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Surface-Plasmon-Resonance-Based Chemical Proteomics: Efficient Specific Extraction and Semiquantitative Identification of Cyclic Nucleotide-Binding Proteins from Cellular Lysates by Using a Combination of Surface Plasmon Resonance, Sequential Elution and
|
0
|
0
|
0
|
0
|
133
|
138
|
11
|
149
|
25
|
0
|
0
|
0
|
0
|
0
|
|
Syntheses via Isoxazolines, Part 25 Amino(hydroxymethyl)cyclopentanetriols, an Emerging Class of Potent Glycosidase Inhibitors - Part I: Synthesis and Evaluation of β-d-Pyranoside Analogues in the manno, glu
|
0
|
0
|
0
|
0
|
9
|
7
|
2
|
9
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Antiapoptotic Activity of a Novel Analogue of the Neutral Sphingomyelinase Inhibitor Scyphostatin
|
0
|
0
|
0
|
0
|
57
|
30
|
8
|
38
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Application of Fluorescent Ras Proteins for Live-Cell Imaging
|
0
|
0
|
0
|
0
|
25
|
26
|
2
|
28
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Application of Integrin Targeting Lipopeptides in Targeted Gene Delivery
|
0
|
0
|
0
|
0
|
77
|
44
|
2
|
46
|
16
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Applications of Chemical Probes for Human O6-Alkylguanine-DNA Alkyltransferase
|
0
|
0
|
0
|
0
|
21
|
10
|
5
|
15
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Biological Activity of a Platinum(II) 6-Phenyl-2,2′-bipyridine Complex and Its Dimeric Analogue
|
0
|
0
|
0
|
0
|
22
|
25
|
1
|
26
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Biological Evaluation of 12,13-Cyclopropyl and 12,13-Cyclobutyl Epothilones
|
0
|
0
|
0
|
0
|
19
|
14
|
3
|
17
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Biological Evaluation of Aza-Epothilones
|
0
|
0
|
0
|
0
|
8
|
13
|
0
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Biological Evaluation of Nonylprodigiosin and Macrocyclic Prodigiosin Analogues
|
0
|
0
|
0
|
0
|
26
|
16
|
2
|
18
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Biological Evaluation of Novel Eg5 Inhibitors
|
0
|
0
|
0
|
0
|
70
|
46
|
9
|
55
|
6
|
0
|
1
|
0
|
0
|
0
|
|
Synthesis and Biological Evaluation of Pyrazolylnaphthoquinones as New Potential Antiprotozoal and Cytotoxic Agents
|
0
|
0
|
0
|
0
|
34
|
12
|
2
|
14
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Biological Investigation of Novel Tricyclic Benzodiazepinedione-Based RGD Analogues
|
0
|
0
|
0
|
0
|
16
|
14
|
0
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Characterisation of Acyl Carrier Protein Bound Polyketide Analogues
|
0
|
0
|
0
|
0
|
17
|
22
|
3
|
25
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Characterization of Oligodeoxynucleotides Containing Naphthyridine:Imidazopyridopyrimidine Base Pairs at their Sticky Ends. Application as Thermally Stabilized Decoy Molecules
|
0
|
0
|
0
|
0
|
37
|
35
|
1
|
36
|
3
|
0
|
0
|
1
|
0
|
0
|
|
Synthesis and Degradation of Nucleic Acid Components by Formamide and Cosmic Dust Analogues
|
0
|
0
|
0
|
0
|
15
|
7
|
2
|
9
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Degradation of Nucleobases and Nucleic Acids by Formamide in the Presence of Montmorillonites
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Degradation of Nucleobases and Nucleic Acids by Formamide in the Presence of Montmorillonites
|
0
|
0
|
0
|
0
|
27
|
11
|
0
|
11
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Evaluation of Organosilicon Inhibitors of Active Purine Transport in Human Osteoblasts
|
0
|
0
|
0
|
0
|
5
|
3
|
1
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Evaluation of Three Novel Scyphostatin Analogues as Neutral Sphingomyelinase Inhibitors
|
0
|
0
|
0
|
0
|
21
|
8
|
1
|
9
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Evaluation of an α-C-Galactosylceramide Analogue that Induces Th1-biased Responses in Human Natural Killer T Cells
|
0
|
0
|
0
|
0
|
97
|
62
|
7
|
69
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Evaluation of an Intercalator-Polyamide Hairpin Designed to Target the Inverted CCAAT Box 2 in the Topoisomerase IIα Promoter
|
0
|
0
|
0
|
0
|
34
|
35
|
4
|
39
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and NMR Structure of Peptidomimetic α4β7-Integrin Antagonists
|
0
|
0
|
0
|
0
|
6
|
4
|
1
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Phenotypic Screening of a Guanine-Mimetic Library
|
0
|
0
|
0
|
0
|
18
|
9
|
1
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Proinflammatory Properties of Muramyl Tripeptides Containing Lysine and Diaminopimelic Acid Moieties
|
0
|
0
|
0
|
0
|
43
|
28
|
0
|
28
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Properties of Aminopropyl Nucleic Acids
|
0
|
0
|
0
|
0
|
31
|
18
|
0
|
18
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Structure-Activity Relationship of the Isoindolinyl Benzisoxazolpiperidines as Potent, Selective, and Orally Active Human Dopamine D4 Receptor Antagonists
|
0
|
0
|
0
|
0
|
33
|
20
|
0
|
20
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Testing of Mechanism-Based Protein-Profiling Probes for Retaining Endo-glycosidases
|
0
|
0
|
0
|
0
|
46
|
32
|
3
|
35
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis and Two-photon Photolysis of 6-(ortho-Nitroveratryl)-Caged IP3 in Living Cells
|
0
|
0
|
0
|
0
|
23
|
19
|
4
|
23
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of 2′-Aminoalkyl-Substituted Fluorinated Nucleobases and Their Influence on the Kinetic Properties of Hammerhead Ribozymes
|
0
|
0
|
0
|
0
|
11
|
14
|
1
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of N-Acetyllactosamine Derivatives with Variation in the Aglycon Moiety for the Study of Inhibition of Sialyl Lewis x Expression
|
0
|
0
|
0
|
0
|
19
|
7
|
0
|
7
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of N-Heteroaryl Retinals and their Artificial Bacteriorhodopsins
|
0
|
0
|
0
|
0
|
25
|
13
|
1
|
14
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Characteristic H-Ras Lipopeptides by Employing Noble-Metal-, Acid-, and Reduction-Labile Blocking Groups
|
0
|
0
|
0
|
0
|
16
|
12
|
0
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Cytidine Ribonucleotides by Stepwise Assembly of the Heterocycle on a Sugar Phosphate
|
0
|
0
|
0
|
0
|
37
|
9
|
1
|
10
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Diazirinyl Photoprobe Carrying a Novel Cleavable Biotin
|
0
|
0
|
0
|
0
|
30
|
25
|
4
|
29
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Epothilone Analogues by Antibody-Catalyzed Resolution of Thiazole Aldol Synthons on a Multigram Scale. Biological Consequences of C-13 Alkylation of Epothilones
|
0
|
0
|
0
|
0
|
7
|
7
|
1
|
8
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Ferroquine Enantiomers: First Investigation of Effects of Metallocenic Chirality upon Antimalarial Activity and Cytotoxicity
|
0
|
0
|
0
|
0
|
22
|
13
|
1
|
14
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of GTP-Derived Ras Ligands
|
0
|
0
|
0
|
0
|
28
|
23
|
0
|
23
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Glycopeptides from Type II Collagen-Incorporating Galactosylated Hydroxylysine Mimetics and Their Use in Studying the Fine Specificity of Arthritogenic T Cells
|
0
|
0
|
0
|
0
|
18
|
8
|
2
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Metal-Carbonyl-Dendrimer-Antibody Immunoconjugates: Towards a New Format for Carbonyl Metallo Immunoassay
|
0
|
0
|
0
|
0
|
18
|
8
|
5
|
13
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Minigramicidin Ion Channels and Test of Their Hydrophobic Match with the Membrane
|
0
|
0
|
0
|
0
|
7
|
4
|
1
|
5
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Neu5Ac Oligosaccharides and Analogues by Transglycosylation and their Binding Properties as Ligands to MAG
|
0
|
0
|
0
|
0
|
24
|
19
|
1
|
20
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of New Boron-Rich Building Blocks for Boron Neutron Capture Therapy or Energy-Filtering Transmission Electron Microscopy
|
0
|
0
|
0
|
0
|
26
|
10
|
1
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Novel Acceptor Substrates for the Dolichyl Phosphate Mannose Synthase from Yeast
|
0
|
0
|
0
|
0
|
20
|
13
|
3
|
16
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Solid-Supported Mirror-Image Sugars: A Novel Method for Selecting Receptors for Cellular-Surface Carbohydrates
|
0
|
0
|
0
|
0
|
18
|
12
|
3
|
15
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Thioether-Linked Analogues of the 2,3-Sialyl-TF and MECA-79 Antigens: Mucin-Type Glycopeptides Associated with Cancer and Inflammation
|
0
|
0
|
0
|
0
|
34
|
15
|
0
|
15
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of Tissues and Organs
|
0
|
0
|
0
|
0
|
38
|
23
|
1
|
24
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of [1,2-13C2,15N]-L-Homoserine and Its Incorporation by the PKS-NRPS System of Fusarium moniliforme into the Myco
|
0
|
0
|
0
|
0
|
56
|
85
|
5
|
90
|
15
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of a C-Glycoside Analogue of β-d-Galactosyl Hydroxynorvaline and Its Use in Immunological Studies
|
0
|
0
|
0
|
0
|
8
|
16
|
0
|
16
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of a 13C-Methyl-Group-Labeled Methionine Precursor as a Useful Tool for Simplifying Protein Structural Analysis by NMR Spectroscopy
|
0
|
0
|
0
|
0
|
37
|
54
|
5
|
59
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis of a Novel Ceramide Analogue and its Use in a High-Throughput Fluorogenic Assay for Ceramidases
|
0
|
0
|
0
|
0
|
58
|
48
|
0
|
48
|
2
|
0
|
1
|
0
|
0
|
0
|
|
Synthesis, Characterization and Biological Activity of trans-Platinum(II) and trans-Platinum(IV) Complexes with 4-Hydroxymethylpyridine
|
0
|
0
|
0
|
0
|
18
|
9
|
1
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis, Inhibition Properties, and Theoretical Study of the New Nanomolar Trehalase Inhibitor 1-Thiatrehazolin: Towards a Structural Understanding of Trehazolin Inhibition
|
0
|
0
|
0
|
0
|
32
|
20
|
1
|
21
|
1
|
0
|
1
|
0
|
0
|
0
|
|
Synthesis, Receptor Binding, Molecular Modeling, and Proliferative Assays of a Series of 17α-Arylestradiols
|
0
|
0
|
0
|
0
|
27
|
14
|
0
|
14
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthesis, Solution Structure and Immune Recognition of an Epidermal Growth Factor-Like Domain from Plasmodium falciparum Merozoite Surface Protein-1
|
0
|
0
|
0
|
0
|
75
|
44
|
9
|
53
|
25
|
0
|
0
|
1
|
0
|
0
|
|
Synthesis, Structural and Biological Studies of Ubiquitin Mutants Containing (2S, 4S)-5-Fluoroleucine Residues Strategically Placed in the Hydrophobic Core
|
0
|
0
|
0
|
0
|
21
|
7
|
2
|
9
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic Carbohydrate Dendrimers, Part 8 Toward the Synthesis of Large Oligosaccharide-Based Dendrimers
|
0
|
0
|
0
|
0
|
17
|
17
|
0
|
17
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic DNA Aptamers to Detect Protein Molecular Variants in a High-Throughput Fluorescence Quenching Assay
|
0
|
0
|
0
|
0
|
133
|
71
|
5
|
76
|
23
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic Ligands Able to Interact with the P53 Tetramerization Domain. Towards Understanding a Protein Surface Recognition Event
|
0
|
0
|
0
|
0
|
43
|
29
|
4
|
33
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic Multivalent Molecules: Concepts and Biomedical Applications. By Seok-Ki Choi.
|
0
|
0
|
0
|
0
|
8
|
4
|
0
|
4
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications and Therapeutic Implications. Edited by Levon M. Khachigian.
|
0
|
0
|
0
|
0
|
13
|
5
|
0
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic Peptide Templates for Molecular Recognition: Recent Advances and Applications
|
0
|
0
|
0
|
0
|
116
|
91
|
6
|
97
|
14
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic Peptides Derived from the Angiostatin K4 Domain Inhibit Endothelial Cell Migration
|
0
|
0
|
0
|
0
|
14
|
4
|
1
|
5
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Synthetic Potential of Molluscan Sulfatases for the Library Synthesis of Regioselectively O-Sulfonated D-Galacto-Sugars
|
0
|
0
|
0
|
0
|
28
|
17
|
1
|
18
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Systematic Regulation of the Enzymatic Activity of Phenylacetaldoxime Dehydratase by Exogenous Ligands
|
0
|
0
|
0
|
0
|
14
|
8
|
0
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Systems Biology and the Molecular Circuits of Cancer
|
0
|
0
|
0
|
0
|
74
|
45
|
7
|
52
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Table of Contents of Issue 6/2004
|
0
|
0
|
0
|
0
|
0
|
1
|
0
|
1
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Tamoxifen Derivatives for Delivery of the Antitumoral (DACH)Pt Group: Selective Synthesis by McMurry Coupling, and Biochemical Behaviour
|
0
|
0
|
0
|
0
|
37
|
72
|
0
|
72
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Target-Assisted Selection of Galactosyltransferase Binders from Dynamic Combinatorial Libraries. An Unexpected Solution with Restricted Amounts of the Enzyme
|
0
|
0
|
0
|
0
|
45
|
41
|
3
|
44
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Target-Family-Oriented Focused Libraries for Kinases - Conceptual Design Aspects and Commercial Availability
|
0
|
0
|
0
|
0
|
38
|
30
|
2
|
32
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Targeting RNA with Small Molecules
|
0
|
0
|
0
|
0
|
50
|
41
|
5
|
46
|
11
|
0
|
0
|
0
|
0
|
0
|
|
Targeting the HIV Trans-Activation Responsive Region - Approaches Towards RNA-Binding Drugs
|
0
|
0
|
0
|
0
|
21
|
19
|
1
|
20
|
13
|
0
|
0
|
0
|
0
|
0
|
|
Template-Directed Assembly of Metallosalen-DNA Hairpin Conjugates
|
0
|
0
|
0
|
0
|
12
|
12
|
1
|
13
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Template-Directed DNA Photoligation in Rapid and Selective Detection of RNA Point Mutations
|
0
|
0
|
0
|
0
|
7
|
6
|
2
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Termination-Free Prokaryotic Protein Translation by Using Anticodon-Adjusted E. coli tRNASer as Unified Suppressors of the UAA/UGA/UAG Stop Codons. Read-Through Ribosome Display of Full-Length DHFR with Translated
|
0
|
0
|
0
|
0
|
21
|
12
|
6
|
18
|
5
|
4
|
0
|
0
|
0
|
0
|
|
Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors
|
0
|
0
|
0
|
0
|
172
|
111
|
19
|
130
|
44
|
0
|
2
|
0
|
0
|
0
|
|
Tetrabutylammonium Fluoride-Mediated Rapid Alkylation Reaction in Microtiter Plates for the Discovery of Enzyme Inhibitors in Situ
|
0
|
0
|
0
|
0
|
14
|
15
|
1
|
16
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The α-to-β Conformational Transition of Alzheimer's Aβ-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of β Conformation Seeding
|
0
|
0
|
0
|
0
|
165
|
118
|
21
|
139
|
36
|
0
|
0
|
0
|
0
|
0
|
|
The 2-Aminogluconate Isomer of Rhizobium sin-1 Lipid A Can Antagonize TNF-α Production Induced by Enteric LPS
|
0
|
0
|
0
|
0
|
47
|
20
|
2
|
22
|
6
|
0
|
0
|
0
|
0
|
0
|
|
The 6-OH Group of d-Inositol 1-Phosphate Serves as an H-Bond Donor in the Catalytic Hydrolysis of the Phosphate Ester by Inositol Monophosphatase
|
0
|
0
|
0
|
0
|
14
|
15
|
2
|
17
|
4
|
0
|
0
|
0
|
0
|
0
|
|
The Activation of Electrophile, Nucleophile and Leaving Group during the Reaction Catalysed by pI258 Arsenate Reductase
|
0
|
0
|
0
|
0
|
21
|
10
|
1
|
11
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Activation of Fibroblast Growth Factors (FGFs) by Glycosaminoglycans: Influence of the Sulfation Pattern on the Biological Activity of FGF-1
|
0
|
0
|
0
|
0
|
35
|
11
|
2
|
13
|
3
|
0
|
0
|
0
|
0
|
0
|
|
The Activation of Fibroblast Growth Factors by Heparin: Synthesis, Structure, and Biological Activity of Heparin-Like Oligosaccharides
|
0
|
0
|
0
|
0
|
18
|
14
|
2
|
16
|
3
|
0
|
0
|
0
|
0
|
0
|
|
The Aptamer Handbook: Functional Oligonucleotides and Their Applications. By S. Klussmann.
|
0
|
0
|
0
|
0
|
21
|
19
|
5
|
24
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The Binding Mode of Progesterone to Its Receptor Deduced from Molecular Dynamics Simulations
|
0
|
0
|
0
|
0
|
11
|
8
|
0
|
8
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The Biosynthesis of Indolocarbazoles in a Heterologous E. coli Host
|
0
|
0
|
0
|
0
|
10
|
9
|
1
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Biosynthesis of Vancomycin-Type Glycopeptide Antibiotics - A Model for Oxidative Side-Chain Cross-Linking by Oxygenases Coupled to the Action of Peptide Synthetases
|
0
|
0
|
0
|
0
|
40
|
27
|
1
|
28
|
6
|
0
|
0
|
0
|
0
|
0
|
|
The Blasticidin S Biosynthesis Gene Cluster from Streptomyces griseochromogenes: Sequence Analysis, Organization, and Initial Characterization
|
0
|
0
|
0
|
0
|
58
|
22
|
8
|
30
|
13
|
0
|
0
|
0
|
0
|
0
|
|
The Cell's Cookbook For Iron-Sulfur Clusters: Recipes For Fool's Gold?
|
0
|
0
|
0
|
0
|
24
|
7
|
2
|
9
|
8
|
0
|
0
|
0
|
0
|
0
|
|
The Chemistry and Biology of Discodermolide
|
0
|
0
|
0
|
0
|
17
|
14
|
0
|
14
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Chemistry and Biology of Nitroxyl (HNO): A Chemically Unique Species with Novel and Important Biological Activity
|
0
|
0
|
0
|
0
|
34
|
18
|
2
|
20
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Chemistry and Biology of Ratjadone
|
0
|
0
|
0
|
0
|
12
|
5
|
1
|
6
|
5
|
0
|
0
|
0
|
0
|
0
|
|
The Compound 13-D Selectively Induces Apoptosis in White Blood Cancers versus Other Cancer Cell Types
|
0
|
0
|
0
|
0
|
44
|
36
|
7
|
43
|
9
|
0
|
0
|
0
|
0
|
0
|
|
The Concept of “Buffering” in Systems and Control Theory: From Metaphor to Math
|
0
|
0
|
0
|
0
|
20
|
14
|
0
|
14
|
3
|
0
|
0
|
0
|
0
|
0
|
|
The Conformation of B18 Peptide in the Presence of Fluorinated and Alkylated Nanoparticles
|
0
|
0
|
0
|
0
|
13
|
9
|
0
|
9
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The Consequences of Lysosomotropism on the Design of Selective Cathepsin K Inhibitors
|
0
|
0
|
0
|
0
|
74
|
66
|
4
|
70
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Coordination Chemistry of Fluorine in Fluorocarbons
|
0
|
0
|
0
|
0
|
19
|
19
|
1
|
20
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The Core Structures of Roseophilin and the Prodigiosin Alkaloids Define a New Class of Protein Tyrosine Phosphatase Inhibitors
|
0
|
0
|
0
|
0
|
24
|
16
|
0
|
16
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The Dipeptide H-Trp-Glu-OH Shows Highly Antagonistic Activity against PPARγ: Bioassay with Molecular Modeling Simulation
|
0
|
0
|
0
|
0
|
63
|
38
|
11
|
49
|
9
|
0
|
1
|
0
|
0
|
0
|
|
The Discovery of Novel Protein Kinase Inhibitors by Using Fragment-Based High-Throughput X-ray Crystallography
|
0
|
0
|
0
|
0
|
73
|
47
|
10
|
57
|
12
|
0
|
0
|
0
|
0
|
0
|
|
The Effects of Ligand Exchange and Mobility on the Peroxidase Activity of a Bacterial Cytochrome c upon Unfolding
|
0
|
0
|
0
|
0
|
18
|
2
|
2
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The Ether Lipid Inositol-C2-PAF is a Potent Inhibitor of Cell Proliferation in HaCaT Cells
|
0
|
0
|
0
|
0
|
37
|
15
|
0
|
15
|
4
|
0
|
0
|
0
|
0
|
0
|
|
The Expanding Role of Mass Spectrometry in Metabolite Profiling and Characterization
|
0
|
0
|
0
|
0
|
98
|
57
|
5
|
62
|
9
|
0
|
0
|
0
|
0
|
0
|
|
The Experimentally Elusive Oxidant of Cytochrome P450: A Theoretical “Trapping” Defining More Closely the “Real” Species
|
0
|
0
|
0
|
0
|
6
|
9
|
1
|
10
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The First Example of an RNA Urea Synthase: Selection through the Enzyme Active Site of Human Neutrophile Elastase
|
0
|
0
|
0
|
0
|
7
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The First Orally Active Low Molecular Weight Agonists for the LH Receptor: Thienopyr(im)idines with Therapeutic Potential for Ovulation Induction
|
0
|
0
|
0
|
0
|
18
|
11
|
1
|
12
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The First View of an ABC Transporter: The X-ray Crystal Structure of MsbA from E. coli
|
0
|
0
|
0
|
0
|
16
|
5
|
2
|
7
|
3
|
0
|
0
|
0
|
0
|
0
|
|
The Folding and Unfolding Kinetics of the i-Motif Structure Formed by the C-Rich Strand of Human Telomere DNA
|
0
|
0
|
0
|
0
|
28
|
24
|
1
|
25
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Fumitremorgin Gene Cluster of Aspergillus fumigatus: Identification of a Gene Encoding Brevianamide F Synthetase
|
0
|
0
|
0
|
0
|
72
|
49
|
7
|
56
|
6
|
0
|
1
|
0
|
0
|
0
|
|
The Functional Role of Selenocysteine (Sec) in the Catalysis Mechanism of Large Thioredoxin Reductases: Proposition of a Swapping Catalytic Triad Including a Sec-His-Glu State
|
0
|
0
|
0
|
0
|
20
|
11
|
3
|
14
|
9
|
0
|
0
|
0
|
0
|
0
|
|
The G Protein-Coupled Receptors Handbook. Edited by Lakshami A. Devi.
|
0
|
0
|
0
|
0
|
10
|
5
|
1
|
6
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Hammerhead Ribozyme Structure Brought in Line
|
0
|
0
|
0
|
0
|
108
|
78
|
18
|
96
|
19
|
0
|
0
|
0
|
0
|
0
|
|
The Highly Exposed Loop Region in Mammalian Purple Acid Phosphatase Controls the Catalytic Activity
|
0
|
0
|
0
|
0
|
13
|
7
|
1
|
8
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Identification of an Adenovirus Receptor by Using Affinity Capture and Mass Spectrometry
|
0
|
0
|
0
|
0
|
27
|
12
|
0
|
12
|
9
|
0
|
0
|
0
|
0
|
0
|
|
The Impact of R53C Mutation on the Three-Dimensional Structure, Stability, and DNA-Binding Properties of the Human Hesx-1 Homeodomain
|
0
|
0
|
0
|
0
|
8
|
4
|
0
|
4
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The In Vitro Characterization of the Erythronolide Mycarosyltransferase EryBV and Its Utility in Macrolide Diversification
|
0
|
0
|
0
|
0
|
133
|
174
|
11
|
185
|
21
|
0
|
0
|
0
|
0
|
0
|
|
The Influence of Fluorinated Molecules (Semiochemicals and Enzyme Substrate Analogues) on the Insect Communication System
|
0
|
0
|
0
|
0
|
38
|
18
|
1
|
19
|
12
|
0
|
0
|
1
|
0
|
0
|
|
The Inhibitory Glycine Receptor - Simple Views of a Complicated Channel
|
0
|
0
|
0
|
0
|
38
|
36
|
3
|
39
|
8
|
0
|
0
|
0
|
0
|
0
|
|
The Large Fragment of Escherichia coli DNA Polymerase I Can Synthesize DNA Exclusively from Fluorescently Labeled Nucleotides
|
0
|
0
|
0
|
0
|
10
|
10
|
4
|
14
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Malaria Pigment Haemozoin - A Focal Point of Action for Antimalarial Drugs
|
0
|
0
|
0
|
0
|
46
|
16
|
8
|
24
|
13
|
0
|
0
|
0
|
0
|
0
|
|
The Mechanism of Phosphorylation of Natural Nucleosides and Anti-HIV Analogues by Nucleoside Diphosphate Kinase Is Independent of Their Sugar Substituents
|
0
|
0
|
0
|
0
|
8
|
3
|
3
|
6
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Missing Link in COS Metabolism: A Model Study on the Reactivation of Carbonic Anhydrase from its Hydrosulfide Analogue
|
0
|
0
|
0
|
0
|
30
|
33
|
1
|
34
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The Molecular Arrangement of Membrane-Bound Annexin A2-S100A10 Tetramer as Revealed by Scanning Force Microscopy
|
0
|
0
|
0
|
0
|
17
|
6
|
0
|
6
|
6
|
0
|
0
|
0
|
0
|
0
|
|
The Molecular Basis for A-Site Mutations Conferring Aminoglycoside Resistance: Relationship between Ribosomal Susceptibility and X-ray Crystal Structures
|
0
|
0
|
0
|
0
|
25
|
14
|
1
|
15
|
8
|
0
|
0
|
0
|
0
|
0
|
|
The Molecular Mechanism of Bee Venom Phospholipase A2 Inactivation by Bolinaquinone
|
0
|
0
|
0
|
0
|
51
|
25
|
0
|
25
|
13
|
0
|
0
|
0
|
0
|
0
|
|
The Molecular Mechanism of Membrane Proteins Probed by Evanescent Infrared Waves
|
0
|
0
|
0
|
0
|
26
|
19
|
1
|
20
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Molecular Mechanism of the Termination of Insect Diapause, Part 1: A Timer Protein, TIME-EA4, in the Diapause Eggs of the Silkworm Bombyx mori is a Metallo-Glycoprotein
|
0
|
0
|
0
|
0
|
35
|
15
|
5
|
20
|
9
|
0
|
0
|
0
|
0
|
0
|
|
The Multiplasmid Approach: A New Perspective for Combinatorial Biosynthesis
|
0
|
0
|
0
|
0
|
11
|
8
|
0
|
8
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Outstanding Biological Stability of β- and γ-Peptides toward Proteolytic Enzymes: An In Vitro Investigation with Fifteen Peptidases
|
0
|
0
|
0
|
0
|
36
|
25
|
4
|
29
|
7
|
0
|
0
|
0
|
0
|
0
|
|
The Oxidative Ring Cleavage in Jadomycin Biosynthesis: A Multistep Oxygenation Cascade in a Biosynthetic Black Box
|
0
|
0
|
0
|
0
|
30
|
20
|
1
|
21
|
6
|
0
|
0
|
0
|
0
|
0
|
|
The Polar Hydrophobicity of Fluorinated Compounds
|
0
|
0
|
0
|
0
|
30
|
46
|
1
|
47
|
4
|
0
|
0
|
0
|
0
|
0
|
|
The RAD6 Pathway: Control of DNA Damage Bypass and Mutagenesis by Ubiquitin and SUMO
|
0
|
0
|
0
|
0
|
111
|
69
|
18
|
87
|
20
|
0
|
0
|
0
|
0
|
0
|
|
The RNA-Bound Conformation of Neamine as Determined by Transferred NOE Experiments
|
0
|
0
|
0
|
0
|
21
|
12
|
2
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The RNA-Cleaving Bipartite DNAzyme Is a Distinctive Metalloenzyme
|
0
|
0
|
0
|
0
|
48
|
21
|
4
|
25
|
4
|
0
|
0
|
0
|
0
|
0
|
|
The Reaction of Hydrogen Atoms with Methionine Residues: A Model of Reductive Radical Stress Causing Tandem Protein-Lipid Damage
|
0
|
0
|
0
|
0
|
29
|
19
|
1
|
20
|
4
|
0
|
0
|
0
|
0
|
0
|
|
The Ribosome Functions as a Ribozyme
|
0
|
0
|
0
|
0
|
18
|
7
|
3
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Role of Internal Water Molecules in the Structure and Function of the Rhodopsin Family of G Protein-Coupled Receptors
|
0
|
0
|
0
|
0
|
101
|
124
|
17
|
141
|
25
|
0
|
0
|
0
|
0
|
0
|
|
The Role of an Aliphatic-Aromatic Interaction in the Stabilization of a Model β-Hairpin Peptide
|
0
|
0
|
0
|
0
|
23
|
10
|
7
|
17
|
3
|
0
|
0
|
0
|
0
|
0
|
|
The Role of the 11-cis-Retinal Ring Methyl Substituents in Visual Pigment Formation
|
0
|
0
|
0
|
0
|
25
|
19
|
1
|
20
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Selectivity for Cysteine over Serien in Coenzyme A Biosynthesis
|
0
|
0
|
0
|
0
|
0
|
2
|
0
|
2
|
0
|
0
|
0
|
0
|
0
|
0
|
|
The Selectivity for Cysteine over Serine in Coenzyme A Biosynthesis
|
0
|
0
|
0
|
0
|
7
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The Solution Structure of the AppA BLUF Domain: Insight into the Mechanism of Light-Induced Signaling
|
0
|
0
|
0
|
0
|
35
|
29
|
8
|
37
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Structural Basis for Docking in Modular Polyketide Biosynthesis
|
0
|
0
|
0
|
0
|
41
|
27
|
6
|
33
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Structural Plasticity of the C Terminus of p21Cip1 is a Determinant for Target Protein Recognition
|
0
|
0
|
0
|
0
|
18
|
5
|
1
|
6
|
4
|
0
|
0
|
0
|
0
|
0
|
|
The Structures of Organelles and Reticula: Localised Bioenergetics and Metabolism
|
0
|
0
|
0
|
0
|
8
|
2
|
1
|
3
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The Substrate Specificity of a Recombinant Cysteine Protease from Leishmania mexicana: Application of a Combinatorial Peptide Library Approach
|
0
|
0
|
0
|
0
|
11
|
13
|
0
|
13
|
4
|
0
|
0
|
0
|
0
|
0
|
|
The Synthesis of Small-Molecule Rhamnosides through the Rational Design of a Whole-Cell Biocatalysis System
|
0
|
0
|
0
|
0
|
31
|
29
|
19
|
48
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Systems Biology of Glycosylation
|
0
|
0
|
0
|
0
|
52
|
43
|
3
|
46
|
5
|
0
|
0
|
0
|
0
|
0
|
|
The Target Discovery Process
|
0
|
0
|
0
|
0
|
83
|
69
|
6
|
75
|
22
|
0
|
1
|
0
|
0
|
0
|
|
The Ternary Complex of Cytochrome f and Cytochrome c: Identification of a Second Binding Site and Competition for Plastocyanin Binding
|
0
|
0
|
0
|
0
|
5
|
4
|
1
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
The Transcriptional Coactivator p300 Plays a Critical Role in the Hypertrophic and Protective Pathways Induced by Phenylephrine in Cardiac Cells but Is Specific to the Hypertrophic Effect of Urocortin
|
0
|
0
|
0
|
0
|
50
|
30
|
7
|
37
|
2
|
0
|
0
|
0
|
0
|
0
|
|
The Unique Role of Fluorine in the Design of Active Ingredients for Modern Crop Protection
|
0
|
0
|
0
|
0
|
65
|
40
|
4
|
44
|
16
|
0
|
2
|
0
|
0
|
0
|
|
Thermodynamic Control of Electron Transfer Rates in Multicentre Redox Proteins
|
0
|
0
|
0
|
0
|
22
|
6
|
3
|
9
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Thermostabilization of a Cytochrome P450 Peroxygenase
|
0
|
0
|
0
|
0
|
17
|
15
|
0
|
15
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Thermostable Glycosynthases and Thioglycoligases Derived from Thermotoga maritima β-Glucuronidase
|
0
|
0
|
0
|
0
|
49
|
22
|
9
|
31
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Thiooligosaccharides as Tools for Structural Biology
|
0
|
0
|
0
|
0
|
43
|
30
|
3
|
33
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Tight Binding of the Antitumor Drug Ditercalinium to Quadruplex DNA
|
0
|
0
|
0
|
0
|
27
|
16
|
4
|
20
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Titanium Implant Materials with Improved Biocompatibility through Coating with Phosphonate-Anchored Cyclic RGD Peptides
|
0
|
0
|
0
|
0
|
71
|
42
|
1
|
43
|
11
|
0
|
0
|
1
|
0
|
0
|
|
Tools for Glycomics: Mapping Interactions of Carbohydrates in Biological Systems
|
0
|
0
|
0
|
0
|
160
|
85
|
13
|
98
|
21
|
0
|
0
|
0
|
0
|
0
|
|
Total Enantioselective Synthesis and In Vivo Biological Evaluation of a Novel Fluorescent BODIPY α-Galactosylceramide
|
0
|
0
|
0
|
0
|
40
|
26
|
2
|
28
|
7
|
0
|
0
|
0
|
0
|
0
|
|
Total Synthesis and Biological Activity of 13,14-Dehydro-12-Oxo-Phytodienoic Acids (Deoxy-J1-Phytoprostanes)
|
0
|
0
|
0
|
0
|
16
|
14
|
0
|
14
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Total Synthesis and Biological Assessment of Benzimidazole-Based Analogues of Epothilone A: Ambivalent Effects on Cancer Cell Growth Inhibition
|
0
|
0
|
0
|
0
|
28
|
22
|
1
|
23
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Toward Semisynthetic Lipoproteins by Convergent Strategies Based on Click and Ligation Chemistry
|
0
|
0
|
0
|
0
|
78
|
60
|
4
|
64
|
15
|
0
|
0
|
0
|
0
|
0
|
|
Towards Proto-Cells: “Primitive” Lipid Vesicles Encapsulating Giant DNA and Its Histone Complex
|
0
|
0
|
0
|
0
|
13
|
8
|
2
|
10
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Towards the Generation of Artificial O6-Alkylguanine-DNA Alkyltransferases: In Vitro Selection of Antibodies with Reactive Cysteine Residues
|
0
|
0
|
0
|
0
|
13
|
2
|
2
|
4
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Transforming Carbonic Anhydrase into Epoxide Synthase by Metal Exchange
|
0
|
0
|
0
|
0
|
21
|
22
|
2
|
24
|
0
|
0
|
1
|
0
|
0
|
0
|
|
Transient Protein Interactions between Cytochrome f and the Phytocyanin Umecyanin
|
0
|
0
|
0
|
0
|
4
|
5
|
0
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Transient Structural Ordering of the RNA-Binding Domain of Carnation Mottle Virus p7 Movement Protein Modulates Nucleic Acid Binding
|
0
|
0
|
0
|
0
|
10
|
2
|
2
|
4
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Translational Termination Not Yet at Its End
|
0
|
0
|
0
|
0
|
11
|
5
|
0
|
5
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Transmembrane B-DNA
|
0
|
0
|
0
|
0
|
5
|
8
|
0
|
8
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Transport Of Surface-Modified Nanoparticles Through Cell Monolayers
|
0
|
0
|
0
|
0
|
75
|
46
|
11
|
57
|
6
|
0
|
0
|
0
|
0
|
0
|
|
Triple-Helix Directed Cleavage of Double-Stranded DNA by Benzoquinoquinoxaline-1,10-phenanthroline Conjugates
|
0
|
0
|
0
|
0
|
41
|
24
|
0
|
24
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Tunable DNA Cleavage by Intercalating Peptidoconjugates
|
0
|
0
|
0
|
0
|
42
|
25
|
3
|
28
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Two Nucleophilic Mutants of the Micromonospora viridifaciens Sialidase Operate with Retention of Configuration by Two Different Mechanisms
|
0
|
0
|
0
|
0
|
20
|
11
|
3
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Two-Dimensional Multiarray Formation of Hepatocyte Spheroids on a Microfabricated PEG-Brush Surface
|
0
|
0
|
0
|
0
|
60
|
40
|
0
|
40
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Type II Thioesterase Restores Activity of a NRPS Module Stalled with an Aminoacyl-S-enzyme that Cannot Be Elongated
|
0
|
0
|
0
|
0
|
17
|
10
|
4
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Ubiquitin Binds to a Short Peptide Segment of Hydrolase UCH-L3: A Study by FCS, RIfS, ITC and NMR
|
0
|
0
|
0
|
0
|
167
|
149
|
20
|
169
|
33
|
2
|
0
|
0
|
0
|
0
|
|
Understanding Biology at the Molecular Level
|
0
|
0
|
0
|
0
|
9
|
13
|
3
|
16
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Unexpected Oxidation of a Depsipeptide Substrate Analogue in Crystalline Isopenicillin N Synthase
|
0
|
0
|
0
|
0
|
38
|
32
|
7
|
39
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Unexpected Puckering of Hydroxyproline in the Guest Triplets, Hyp-Pro-Gly and Pro-alloHyp-Gly Sandwiched between Pro-Pro-Gly Sequence
|
0
|
0
|
0
|
0
|
14
|
8
|
3
|
11
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Unprecedented Diversity of Catalytic Domains in the First Four Modules of the Putative Pederin Polyketide Synthase
|
0
|
0
|
0
|
0
|
34
|
21
|
4
|
25
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Unusually Strong Positive Cooperativity in Binding of Peptides to Latent Membrane Protein-1 DNA Fragments of the Epstein-Barr Viral Gene
|
0
|
0
|
0
|
0
|
27
|
18
|
1
|
19
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Urdamycin L: A Novel Metabolic Shunt Product that Provides Evidence for the Role of the urdM Gene in the Urdamycin A Biosynthetic Pathway of Streptomyces fradiae TÜ 2717
|
0
|
0
|
0
|
0
|
11
|
8
|
0
|
8
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Use of “Tethering” for the Identification of a Small Molecule that Binds to a Dynamic Hot Spot on the Interleukin-2 Surface
|
0
|
0
|
0
|
0
|
20
|
10
|
0
|
10
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Use of Click Chemistry to Define the Substrate Specificity of Leishmania β-1,2-Mannosyltransferases
|
0
|
0
|
0
|
0
|
154
|
92
|
8
|
100
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Use of Fluorine in the Medicinal Chemistry and Chemical Biology of Bioactive Compounds - A Case Study on Fluorinated Taxane Anticancer Agents
|
0
|
0
|
0
|
0
|
43
|
56
|
6
|
62
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Use of Magnetic Nanoparticles as Nanosensors to Probe for Molecular Interactions
|
0
|
0
|
0
|
0
|
153
|
79
|
1
|
80
|
22
|
0
|
0
|
0
|
0
|
0
|
|
Use of Short Duplexes for the Analysis of the Sequence-Dependent Cleavage of DNA by a Chemical Nuclease, a Manganese Porphyrin
|
0
|
0
|
0
|
0
|
13
|
13
|
1
|
14
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Using Selection to Identify and Chemical Microarray to Study the RNA Internal Loops Recognized by 6′-N-Acylated Kanamycin A
|
0
|
0
|
0
|
0
|
16
|
18
|
5
|
23
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Utilization of L-α-Nucleobase Amino Acids (NBAs) as Protein Engineering Tools: Construction of NBA-Modified HIV-1 Protease Analogues and Enhancement of Dimerization Induced by Nucleobase Interaction
|
0
|
0
|
0
|
0
|
14
|
6
|
0
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Utilizing the Power of Microbial Genetics to Bridge the Gap Between the Promise and the Application of Marine Natural Products
|
0
|
0
|
0
|
0
|
126
|
73
|
13
|
86
|
18
|
0
|
0
|
0
|
0
|
0
|
|
ValC, a New Type of C7-Cyclitol Kinase Involved in the Biosynthesis of the Antifungal Agent Validamycin A
|
0
|
0
|
0
|
0
|
62
|
71
|
1
|
72
|
8
|
0
|
0
|
0
|
0
|
0
|
|
Vancomycin Resistance: Small Molecule Approaches Targeting the Bacterial Cell Wall Biosynthesis
|
0
|
0
|
0
|
0
|
13
|
10
|
3
|
13
|
2
|
0
|
0
|
0
|
0
|
0
|
|
Variations of the 2-His-1-carboxylate Theme in Mononuclear Non-Heme FeII Oxygenases
|
0
|
0
|
0
|
0
|
50
|
41
|
6
|
47
|
10
|
0
|
0
|
0
|
0
|
0
|
|
Varied DNA Polymerase - Substrate Interactions in the Nucleotide Binding Pocket
|
0
|
0
|
0
|
0
|
7
|
10
|
1
|
11
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Vector Systems for the Delivery of Small Interfering RNAs: Managing the RISC
|
0
|
0
|
0
|
0
|
22
|
10
|
1
|
11
|
4
|
0
|
0
|
0
|
0
|
0
|
|
Vinyl-Pyridinium Triphenylamines: Novel Far-Red Emitters with High Photostability and Two-Photon Absorption Properties for Staining DNA
|
0
|
0
|
0
|
0
|
58
|
128
|
6
|
134
|
7
|
0
|
0
|
0
|
0
|
0
|
|
VioC is a Non-Heme Iron, α-Ketoglutarate-Dependent Oxygenase that Catalyzes the Formation of 3S-Hydroxy-L-Arginine during Viomycin Biosynthesis
|
0
|
0
|
0
|
0
|
31
|
27
|
8
|
35
|
5
|
0
|
0
|
0
|
0
|
0
|
|
Virtual Screening in Drug Discovery. Edited by Juan Alvarez and Brian Shoichet.
|
0
|
0
|
0
|
0
|
5
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Visualization of Annexin I Binding to Calcium-Induced Phosphatidylserine Domains
|
0
|
0
|
0
|
0
|
7
|
2
|
3
|
5
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Water Exclusion and Enantioselectivity in Catalysis
|
0
|
0
|
0
|
0
|
39
|
37
|
7
|
44
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Ways of Assembling Complex Natural Products on Modular Nonribosomal Peptide Synthetases
|
0
|
0
|
0
|
0
|
94
|
72
|
11
|
83
|
34
|
0
|
0
|
0
|
0
|
0
|
|
Web Site: RNA for everyone! The RNA World Website at IMB Jena
|
0
|
0
|
0
|
0
|
3
|
1
|
2
|
3
|
0
|
0
|
0
|
0
|
0
|
0
|
|
Web Site: Web Sites about G-Protein-Coupled Receptors
|
0
|
0
|
0
|
0
|
5
|
6
|
1
|
7
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Wedgelike Glycodendrimers as Inhibitors of Binding of Mammalian Galectins to Glycoproteins, Lactose Maxiclusters, and Cell Surface Glycoconjugates
|
0
|
0
|
0
|
0
|
33
|
28
|
2
|
30
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Withstanding the Test of Time
|
0
|
0
|
0
|
0
|
11
|
56
|
13
|
69
|
1
|
0
|
0
|
0
|
0
|
0
|
|
Worms, Life, and Death (Nobel Lecture)
|
0
|
0
|
0
|
0
|
44
|
32
|
5
|
37
|
9
|
0
|
0
|
0
|
0
|
0
|
|
Yeast Prion-Protein, Sup35, Fibril Formation Proceeds by Addition and Substraction of Oligomers
|
0
|
0
|
0
|
0
|
46
|
31
|
2
|
33
|
4
|
0
|
0
|
0
|
0
|
0
|
|
[7-(Dialkylamino)coumarin-4-yl]methyl-Caged Compounds as Ultrafast and Effective Long-Wavelength Phototriggers of 8Bromo-Substituted Cyclic Nucleotides
|
0
|
0
|
0
|
0
|
44
|
32
|
2
|
34
|
6
|
0
|
0
|
0
|
0
|
0
|
|
[i]lab Workshop on Systems Biology Challenges Chemistry
|
0
|
0
|
0
|
0
|
13
|
2
|
0
|
2
|
1
|
0
|
0
|
0
|
0
|
0
|
|
cDNA-Protein Fusions: Covalent Protein-Gene Conjugates for the In Vitro Selection of Peptides and Proteins
|
0
|
0
|
0
|
0
|
30
|
19
|
4
|
23
|
2
|
0
|
1
|
0
|
0
|
0
|
|
i[lab] Workshop on RNA Targeting 2003 in Wiesbaden
|
0
|
0
|
0
|
0
|
6
|
2
|
0
|
2
|
2
|
0
|
0
|
0
|
0
|
0
|
|
mRNA Openers and Closers: Modulating AU-Rich Element-Controlled mRNA Stability by a Molecular Switch in mRNA Secondary Structure
|
0
|
0
|
0
|
0
|
101
|
60
|
6
|
66
|
18
|
0
|
0
|
0
|
0
|
0
|
|
pH-Dependent Binding Modes Observed in Trypsin Crystals: Lessons for Structure-Based Drug Design
|
0
|
0
|
0
|
0
|
11
|
6
|
2
|
8
|
3
|
0
|
0
|
0
|
0
|
0
|
|
Total
|
0
|
0
|
0
|
0
|
57470
|
45229
|
5482
|
50711
|
8491
|
53
|
68
|
27
|
0
|
0
|